- Photoreceptor and optogenetics research
- Advanced biosensing and bioanalysis techniques
- Supramolecular Self-Assembly in Materials
- Silk-based biomaterials and applications
- Gold and Silver Nanoparticles Synthesis and Applications
- Electrospun Nanofibers in Biomedical Applications
- Nanoparticle-Based Drug Delivery
- Neural dynamics and brain function
- Nanocluster Synthesis and Applications
- Protein Interaction Studies and Fluorescence Analysis
- Organ Transplantation Techniques and Outcomes
- Advanced Sensor and Energy Harvesting Materials
- Quantum Dots Synthesis And Properties
- Neuroscience and Neural Engineering
- RNA Interference and Gene Delivery
- DNA and Nucleic Acid Chemistry
- Carbon and Quantum Dots Applications
- Neuroscience and Neuropharmacology Research
- Nanoplatforms for cancer theranostics
- Cancer Research and Treatments
- Chemical Synthesis and Analysis
- Medical Research and Treatments
- Photosynthetic Processes and Mechanisms
- Advanced Surface Polishing Techniques
- Parkinson's Disease Mechanisms and Treatments
University of Shanghai for Science and Technology
2013-2025
University of Missouri
2025
University of Chinese Academy of Sciences
2021-2025
Inner Mongolia Agricultural University
2014-2025
Soochow University
2008-2025
Shanghai Jiao Tong University
2009-2025
Zunyi Medical University
2017-2025
International Peace Maternity & Child Health Hospital
2025
Northwest A&F University
2025
Duke University
2022-2025
Neural interface technology has made enormous strides in recent years but stimulating electrodes remain incapable of reliably targeting specific cell types (e.g. excitatory or inhibitory neurons) within neural tissue. This obstacle major scientific and clinical implications. For example, there is intense debate among physicians, neuroengineers neuroscientists regarding the relevant recruited during deep brain stimulation (DBS); moreover, many debilitating side effects DBS likely result from...
In modern society, traffic and transportation the manufacturing industry construction industries continuously release large amounts of dust particles into atmosphere, which can cause heavy air pollution, leading to health hazards. The haze disaster, a serious problem in developing countries such as China India, has become one main issues global environmental pollution recent decades. Many filtration technologies have been developed. Air using electrospun fibers that intercept fine...
Graphene oxide (GO), having a large specific surface area and abundant functional groups, provides an ideal substrate for study enzyme immobilization. We demonstrated that the immobilization on GO sheets could take place readily without using any cross-linking reagents additional modification. The atomically flat enabled us to observe immobilized in native state directly atomic force microscopy (AFM). Combining AFM imaging results of molecules their catalytic activity, we illustrated...
Abstract The versatile electrospinning technique is recognized as an efficient strategy to deliver active pharmaceutical ingredients and has gained tremendous progress in drug delivery, tissue engineering, cancer therapy, disease diagnosis. Numerous delivery systems fabricated through regarding the carrier compositions, incorporation techniques, release kinetics, subsequent therapeutic efficacy are presented herein. Targeting for distinct applications, composition of carriers vary from...
Abstract Conducting hydrogels provide great potential for creating designer shape‐morphing architectures biomedical applications owing to their unique solid–liquid interface and ease of processability. Here, a novel nanofibrous hydrogel with significant enzyme‐like activity that can be used as “ink” print flexible electrochemical devices is developed. The self‐assembled from guanosine (G) KB(OH) 4 simultaneous incorporation hemin into the G‐quartet scaffold, giving rise activity. rapid...
Abstract Crosstalk between ion channels and small GTPases is critical during homeostasis disease, but little known about the structural underpinnings of these interactions. TRPV4 a polymodal, calcium-permeable cation channel that has emerged as potential therapeutic target in multiple conditions. Gain-of-function mutations also cause hereditary neuromuscular disease. Here, we present cryo-EM structures human complex with RhoA ligand-free, antagonist-bound closed, agonist-bound open states....
The bigger pictureNanomaterial-driven, soft wearable electronics hold great promise for continuous monitoring of bio-signals, efficient collection physiological data, and on-demand drug delivery. Wearable electronic devices transducing responses into electrical signals have been used in various telemedicine telediagnosis applications, such as real-time vital signs, blood pressure, body temperature, human motion. Combined with radio frequency (RF) technologies, these can transmit health data...
Nanoparticles are finding a rapidly expanding range of applications in research and technology, finally entering our daily life medical, cosmetic or food products. Their ability to invade all regions an organism including cells cellular organelles offers new strategies for medical diagnosis therapy (nanomedicine), but their safe use requires deep knowledge about interactions with biological systems at the molecular level. Upon incorporation, nanoparticles exposed fluids from which they...
Silkworms and spiders generate fibers that exhibit high strength extensibility. The underlying mechanisms involved in processing silk proteins into fiber form remain incompletely understood, resulting the failure to fully recapitulate remarkable properties of native vitro from regenerated solutions. In present study, extensibility silks were achieved by mimicking natural spinning process. Conformational transitions inside micelles, followed aggregation micelles their stabilization as they...