A5017133032- Liver Disease Diagnosis and Treatment
- Geochemistry and Elemental Analysis
- interferon and immune responses
- Polyoxometalates: Synthesis and Applications
- CRISPR and Genetic Engineering
- Paleontology and Stratigraphy of Fossils
- RNA regulation and disease
- Liver physiology and pathology
- Plant Disease Resistance and Genetics
- Horticultural and Viticultural Research
- Genomics and Phylogenetic Studies
- Fermentation and Sensory Analysis
- Yeasts and Rust Fungi Studies
- Food Quality and Safety Studies
- Hepatitis B Virus Studies
International Institute of Molecular and Cell Biology
2019-2023
Abstract Adenosine deaminases (ADARs) catalyze the deamination of adenosine to inosine, also known as A-to-I editing, in RNA. Although editing occurs widely across animals and is well studied, new biological roles are still being discovered. Here, we study role early zebrafish development. We demonstrate that Adar, orthologue mammalian ADAR1, essential for establishing antero-posterior dorso-ventral axes patterning. Genome-wide discovery reveals pervasive maternal earliest zygotic...
Liver fibrosis is a wound-healing response to tissue injury and inflammation hallmarked by the extracellular matrix (ECM) protein deposition in liver parenchyma remodelling. Different cell types of are known play distinct roles response. Hepatocytes endothelial cells receive molecular signals indicating activate hepatic stellate which produce ECM proteins upon their activation. Despite growing knowledge on mechanism underlying general, cell-type-specific gene regulatory network associated...
Saprochaete suaveolens is an ascomycetous yeast that produces a range of fruity flavors and fragrances. Here, we report the high-contiguity genome sequence ex-holotype strain, NRRL Y-17571 (CBS 152.25). The nuclear contains 24.4 Mbp codes for 8,119 predicted proteins.
Chromosome-scale genome assembly of the yeast Saprochaete ingens CBS 517.90 was determined by a combination technologies producing short (HiSeq X; Illumina) and long (MinION; Oxford Nanopore Technologies) reads. The 21.2-Mbp sequence has GC content 36.9% codes for 6,475 predicted proteins.
Abstract Adenosine deaminases (ADARs) catalyze the deamination of adenosine to inosine, also known as A-to-I editing, in RNA. Although editing occurs widely across animals, and is well studied, new biological roles are still being discovered. Here, we study role early zebrafish development. We demonstrate that Adar, orthologue mammalian ADAR1, essential for establishing antero-posterior dorso-ventral axes patterning. Genome-wide discovery revealed pervasive maternal earliest zygotic...
Abstract Background Liver fibrosis is a wound-healing response to tissue injury and inflammation hallmarked by the extracellular matrix (ECM) protein deposition in liver parenchyma remodelling. Different cell types of are known play distinct roles response. Hepatocytes endothelial cells receive molecular signals indicating activate hepatic stellate which produce ECM proteins upon their activation. Despite growing knowledge on mechanism underlying general, cell-type-specific gene regulatory...