Xingzhuang Zhu

ORCID: 0000-0002-6706-2666
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About
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Research Areas
  • RNA modifications and cancer
  • Esophageal Cancer Research and Treatment
  • Lung Cancer Diagnosis and Treatment
  • Medical Imaging Techniques and Applications
  • Radiomics and Machine Learning in Medical Imaging
  • Cancer-related molecular mechanisms research
  • MicroRNA in disease regulation
  • Peptidase Inhibition and Analysis
  • Pancreatic and Hepatic Oncology Research
  • Lung Cancer Treatments and Mutations
  • Ferroptosis and cancer prognosis

Yuhuangding Hospital
2021-2023

Qingdao University
2021-2023

Affiliated Hospital of Qingdao University
2023

Huazhong University of Science and Technology
2022

First Affiliated Hospital of Soochow University
2022

Zhongnan Hospital of Wuhan University
2022

Wuhan University
2022

Soochow University
2022

Background: The basement membranes (BMs) are involved in tumor progression, while few comprehensive analyses to date performed on the role of BM-related gene signatures lung adenocarcinoma (LUAD). Thus, we aimed develop a novel prognostic model LUAD based BMs-related profiling. Methods: profiling and corresponding clinicopathological data were obtained from membrane BASE, Cancer Genome Atlas (TCGA) expression omnibus (GEO) databases. Cox regression least absolute shrinkage selection operator...

10.3389/fgene.2023.1100560 article EN cc-by Frontiers in Genetics 2023-02-09

To assess the predictive values of primary tumor FDG uptake for patients with inoperable stage III non-small cell lung cancer (NSCLC) after concurrent chemoradiotherapy (CCRT).A total 107 diagnosis NSCLC and CCRT were enrolled. The maximum value (SUVmax) was standardized by calculating several ratios between each background tissues. receiver operating characteristics curve (ROC) used to compare power prognostic models. objective response rate (ORR) overall survival (OS) compared analyzed...

10.1186/s12880-023-01067-6 article EN cc-by BMC Medical Imaging 2023-08-15

Background: N7-methylguanosine (m7G) modification plays a crucial role in the development and progression of lung cancers. MicroRNAs (miRNAs) are closely involved programmed cell death mechanism tumor growth. The m7G-associated miRNAs genes adenocarcinoma (LUAD), their prognosis prediction ability LUAD, however, had not been investigated. Methods: RNA transcriptomes, clinical indices, immune scores LUAD patients were searched downloaded from Cancer Genome Atlas (TCGA) ESTIMATE database....

10.31557/apjcp.2023.24.4.1275 article EN cc-by Asian Pacific Journal of Cancer Prevention 2023-04-01

Mitochondrial fission regulator 2 (MTFR2) is associated with mitochondrial fission, while few studies have assessed the associations between MTFR2 expression and clinical characteristics or prognosis of esophageal squamous cell carcinoma (ESCC). In this study, we compared in 6 ESCC tumors relative normal tissues by immunohistochemistry (IHC). To assess effect on clinicopathologic survival, 115 paraffin embedded tissue samples were IHC staining. Furthermore, association clinicopathological...

10.15430/jcp.2021.26.4.250 article EN Journal of Cancer Prevention 2021-12-30

Abstract Bacground: To assess the predictive values of primary tumor FDG uptake for patients with inoperable stage III non-small cell lung cancer (NSCLC) after concurrent chemoradiotherapy (CCRT). Methods: A total 107 diagnosis NSCLC and CCRT were enrolled in this study. The maximum value (SUVmax) was standardized by calculating several ratios between each background tissues. receiver operating characteristics curve (ROC) used to compare power prognostic models. objective response rate (ORR)...

10.21203/rs.3.rs-2114141/v1 preprint EN cc-by Research Square (Research Square) 2022-12-02

Abstract Background: Mitochondrial fission regulator 2 (MTFR2) is associated with mitochondrial fission, while few studies has assessed the associations between MTFR2 expression and clinical characteristics prognosis of esophageal squamous cell carcinoma (ESCC). Methods: We compared in 6 ESCC tumors relative normal tissues by immunochemistry (IHC). To assess effect on clinicopathologic survival, totally 115 paraffin embedded tissue samples were IHC staining. Furthermore, clinicopathological...

10.21203/rs.3.rs-617078/v1 preprint EN cc-by Research Square (Research Square) 2021-06-21
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