A5101881932- Crystallization and Solubility Studies
- Soil Carbon and Nitrogen Dynamics
- X-ray Diffraction in Crystallography
- Protein Degradation and Inhibitors
- Layered Double Hydroxides Synthesis and Applications
- Magnesium Alloys: Properties and Applications
- Chromosomal and Genetic Variations
- Cancer-related Molecular Pathways
- Corrosion Behavior and Inhibition
- Ubiquitin and proteasome pathways
- Genomics and Phylogenetic Studies
- Cardiomyopathy and Myosin Studies
- Microbial Fuel Cells and Bioremediation
- Tracheal and airway disorders
- Metaheuristic Optimization Algorithms Research
- Advanced Nanomaterials in Catalysis
- Liver physiology and pathology
- Organic Light-Emitting Diodes Research
- Food Drying and Modeling
- Misinformation and Its Impacts
- Multiple Myeloma Research and Treatments
- Cystic Fibrosis Research Advances
- Asymmetric Hydrogenation and Catalysis
- Advanced oxidation water treatment
- Thallium and Germanium Studies
Shandong University of Traditional Chinese Medicine
2023-2025
Affiliated Hospital of Shandong University of Traditional Chinese Medicine
2023-2025
Shanghai Institute of Materia Medica
2023-2024
Huaibei Normal University
2024
Chinese Academy of Sciences
2020-2024
Huazhong Agricultural University
2021-2024
Chang'an University
2024
Xi'an University of Science and Technology
2021-2023
University of Chinese Academy of Sciences
2018-2023
East China Normal University
2022-2023
In situ growth of nanostructures on substrates is a strategy for designing highly efficient catalytic materials. Herein, multimetallic CuCoNi oxide nanowires are synthesized in three-dimensional nickel foam (NF) substrate (CuCoNi–NF) by hydrothermal method and applied to peroxydisulfate (PDS) activation as immobilized catalysts. The performance CuCoNi–NF evaluated through the degradation organic pollutants such bisphenol A (BPA) practical wastewater. results indicate that NF not only plays...
Wrist joint tuberculosis(WJ-TB)is a rare manifestation of osteoarticular tuberculosis(OAT).Delayed diagnosis is common and often leads to postponed treatment, resulting in complications such as stiffness persistent pain the affected limb. A 50-year-old man presented with symptoms wrist suggestive WJ-TB.Initially, he was diagnosed traumatic arthritis.However, following series diagnostic tests, final tuberculous arthritis confirmed.The patient underwent effective which led marked improvement...
Proteolysis-targeting chimera (PROTAC) is a powerful technology that can effectively trigger the degradation of target proteins. The intricate interplay among various factors leads to heterogeneous drug response, bringing about significant challenges in comprehending mechanisms. Our study applied data-independent acquisition-based mass spectrometry multidimensional proteome profiling PROTAC (DIA-MPP) uncover efficacy and sensitivity compound. We profiled signal transducer activator...
Desalination represents an effective method for alleviating water scarcity, applying algorithmic techniques to predict the performance of reverse osmosis (RO) desalination plants, Modified Grey Wolf Optimizer (MGWO) based Artificial Neural Networks (ANN) can membrane distillation (MD) equipment. Four experimental inputs are selected: feed salt concentration(35-140 g/h), flow rate(400-600 L/h), evaporator inlet temperature (60-80℃), and condenser (20-30℃). The permeate flux (L/h m2) is...
Background: Defective airway host-defense (e.g., altered mucus properties, ciliary defects) contributes to the pathogenesis of bronchiectasis. This study aims determine whether genetic mutations associated with defective are implicated in Methods: Based on systematic screening 32 frequently reported bronchiectasis-associated genes, we performed next-generation sequencing (NGS) peripheral blood samples from 192 bronchiectasis patients and 100 healthy subjects. The variant distribution...
Cardiomyopathies are the most common clinical and genetic heterogeneity cardiac diseases, contribution in particular plays a major role patients with primary cardiomyopathies. The aim of this study is to investigate cases inherited cardiomyopathy (IC) for potential disease-causing mutations 64 genes reported be associated IC. A total 110 independent or families diagnosed various cardiomyopathies, including hypertrophic cardiomyopathy, dilated restrictive arrhythmogenic right ventricular left...
Although the chloroplast genome (cpDNA) of higher plants is known to exist as a large protein-DNA complex called 'plastid nucleoid', researches on its DNA state and regulatory elements are limited. In this study, we performed assay for transposase-accessible chromatin sequencing (ATAC-seq) five common tissues across grasses, found that accessibility different regions in cpDNA varied widely, with transcribed being highly accessible patterns around gene start end sites varying depending level...
This study simulated the heat- and mass-transfer characteristics of fresh tomatoes by developing a computational fluid dynamics model. The root-mean-square error (RMSE) mean absolute percentage (MAPE) for tomato temperature were 0.579 °C 3.89%, respectively, RMSE MAPE mass loss 0.737 g 9.87%, respectively. Furthermore, effect different cold chain breaking (CCB) parameters on fluctuations in quantified sensitivity analysis. results indicate that CCB increases moisture compared with an...
Layered double hydroxide (LDH) (Mg-Al and Mg-Al-Co) films were prepared on the surface of LA103Z magnesium-lithium alloy by hydrothermal synthesis method. Corrosion resistance binary ternary LDH coatings was studied comparison. Structures two characterized using XRD, FTIR, SEM EDS, corrosion evaluated polarization curve, EIS, hydrogen evolution rate during immersion in 3.5 wt% NaCl solution. Results showed that Mg-Al film tightly bonded to substrate had a large number nanosheets growing...
The performance of three-dimensional biofilm electrode reactors (3D-BERs) in hydrogen autotrophic denitrification is determined by electroactive biofilms. Herein, a self-assembled hybrid (SAHB) developed on granular activated carbon particle electrodes incorporating nano α-Fe2O3. influences operating parameters such as current, influent concentration, and hydraulic retention time (HRT) are investigated well the mechanisms SAHB-improved denitrification. results indicate that SAHB achieves...
The aim of this work is to understand the effects straw and biochar return in soil on content, distribution, stability, relative contribution rate organic carbon for aggregates, which could be used better understanding stability pool protection mechanisms under return. In study, a field experiment was conducted study aggregates sequestration characteristics rape-maize rotation planting system. Five treatments, including control (no material added, CK), (CS), microorganism (CSD), Biochar...
Multiple identity deception (sockpuppetry) has become an increasingly important issue in the social media environment, because they are engaged undesired behaviors such as spreading rumors, posting hate speeches. The case of blocked users initiating new accounts, called sockpuppets, is widely known and past efforts, which have attempted to detect users, been primarily based on verbal features non-verbal like habits. Although these methods achieved a certain degree success, it easy for smart...
Direct modulation of the non-kinase functions cyclin and CDK-cyclin complexes poses challenges. We utilize hydrophobic tag (HyT) based small-molecule degraders induced degradation T1 its corresponding kinase partner CDK9. LL-CDK9-12 demonstrated most potent selective ability, with DC50 values 0.362 μM against CDK9 0.680 T1. In prostate cancer cells, showed enhanced anti-proliferative activity than parental molecule SNS032 LL-K9-3, previous reported CDK9-cyclin degrader. Moreover, suppressed...
Abstract Layered double hydroxides (LDH) are widely used in the field of Mg alloy surface protection due to their interlayer anion exchangeable and physical barrier. To explore effect corrosion inhibitor modification on growth resistance LDH coating, MgAl‐NO 3 − ‐LDH precursor film was obtained LA43M by situ method, then MgAl‐V 2 O 7 4− ‐LDH, MgAl Cl MgAl‐ASP‐LDH were prepared ion exchange method. The morphology, composition, with different intercalation studied systematically scanning...
The effects of different straw and biochar applications on the carbon balance a farmland ecosystem were studied under rape-maize rotation planting system. study explored impact addition soil sequestration. A field experiment was carried out at National Monitor Station Soil Fertility Fertilizer Efficiency Purple Soils (Chongqing, China). Five treatments, i.e., control (CK, no organic material), only (CS), microorganism (CSD), half (CSBC), (BC), applied. In-situ cumulative emissions total...
Greenhouse gases mainly come from farmland soils. Re-spreading chaff (straw returning) is an effective ecological management in China. Quantitative analysis of straw residues together with reduced fertilization rates can provide a scientific basis for reducing greenhouse gas emissions. A field experiment six different fertilizer amounts combined was carried out vegetable (lettuce-cabbage-chili rotation), including the control (CK), conventional fertilizing (F), returning 100% (100FS), 70%...
Targeted protein degradation technology can achieve the modulation of undruggable proteins. Abnormal activation cyclins promote tumorigenesis and tumor progression. However, regard to be with no small-molecule binders had been released. Here, we utilize hydrophobic tag (HyT)-based degraders induced cyclin T1 its corresponding kinase partner CDK9. We describe discovery a series novel dual CDK9-cyclin T1. LL-CDK9-12 demonstrated most potent selective ability, DC50 values 0.362 μM against CDK9...