A.S. Golderova

ORCID: 0000-0002-6739-9453
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About
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Research Areas
  • Human Health and Disease
  • Healthcare Systems and Public Health
  • Immunotherapy and Immune Responses
  • Cervical Cancer and HPV Research
  • Thermal Regulation in Medicine
  • Physical Education and Training Studies
  • Medical and Agricultural Research Studies
  • Biochemical effects in animals
  • Liver Disease Diagnosis and Treatment
  • Hepatitis C virus research
  • Exercise and Physiological Responses
  • Immunodeficiency and Autoimmune Disorders
  • Hepatitis B Virus Studies
  • Electrospun Nanofibers in Biomedical Applications
  • Cardiovascular Health and Risk Factors
  • Intellectual Property Rights and Media
  • Healthcare and Venom Research
  • Genomics, phytochemicals, and oxidative stress
  • Acute Kidney Injury Research
  • Cardiovascular Disease and Adiposity
  • Genetics and Physical Performance
  • Polish Law and Legal System
  • Inhalation and Respiratory Drug Delivery
  • Body Composition Measurement Techniques
  • Pharmacological Effects of Natural Compounds

North-Eastern Federal University
2018-2024

Academy of Sciences of the Republic of Sakha
2019

Krasnoyarsk State Medical University
2018

University of Latvia
2018

Latvia University of Life Sciences and Technologies
2018

Unidad de Cirugía Artroscópica
2018

Foundation for Ichthyosis and Related Skin Types
2018

The assessment of metabolic parameters in students engaged boxing at the training stage was carried out. According to results study, normal functional body, BMI, and satisfactory AP were established. biochemical parameters, group athletes showed an excess range values CK, HDL, a decrease LDL de Ritis coefficient (CDR), beginner – increase CDR VLDL. Significant differences between groups found TG, VLDL (p<0.005), HDL glucose KA (p<0.05). indicators indicating formed adaptive changes...

10.25789/ymj.2025.89.06 article EN cc-by Yakut Medical Journal 2025-03-18

Changes in metabolism at high latitudes are a physiological adaptation to "northern stress" caused by the influence of meteorological and heliogeophysical factors. The study metabolic blood parameters can serve assess risk developing disease future due decrease body's adaptive reserves when it is influenced environmental factors various nature. stress potential natural northern climatic geophysical may increase relation those people who come North from regions with temperate climate work...

10.25587/2587-5590-2024-1-70-77 article EN cc-by Vestnik of North-Eastern Federal University Medical Sciences 2024-03-31

Significance. Objective health indicators of northerners are worse than those residents more southern regions. Nutrition, as a long-term factor affecting health, deserves higher attention: it should not only be complete, balanced, appropriate for physical activity and gender, but also take into account climatic geographical living conditions, national characteristics habits. The purpose the study is to analyze relationship between eating habits morbidity among two Arctic regions Republic...

10.21045/2071-5021-2024-70-3-9 article EN Social Aspects of Population Health 2024-01-01

Introduction . Studies have shown that natural compounds from various plants including berries can antitumor activity. We examined Phlojodicarpus sibiricus extract as well homogenates of wild such hawthorn, cranberry, brier; all these contain a variety biologically active compounds: flavonoids, carotenoids, anthocyanins and other polyphenols. Aim To evaluate cytotoxicity growing in Northwestern Siberia Michigan Cancer Foundation-7 (MCF-7) breast cancer cell line using the МТТ assay....

10.17650/2313-805x-2024-11-3-126-132 article EN cc-by Advances in molecular oncology 2024-10-11

The article investigates the effect of Phlojodicarpus sibiricus extract on cytokine status C57Bl/6 mice with transplanted melanoma. sibiricus, also known as Siberian phlojodicarpus, is a perennial herbaceous plant belonging to Apiaceae family. It widely distributed in Siberia and Russian Far East. was administered orally at dosage 100 mg/ml, concentrations cytokines such IL-2, IL-4, IL-5, IL-10, IL-12, TNF-α, IFN-γ, GM-CSF were assessed. experiment included three groups mice: control group,...

10.26787/nydha-2618-8783-2024-9-4-52-57 article EN Bulletin Biomedicine and sociology 2024-12-29

Objective: to determine the awareness of adult population Sakha Republic (Yakutia) about viral hepatitis and measures for its prevention. Material methods. An anonymous survey (n=226, 128 women 98 men aged 18-76 years) on risk factors prevention was conducted using a specially prepared questionnaire. Results. A low level established, only 22.4% respondents consider their knowledge sufficient, third did not know whether they are vaccinated against hepatitis, 49.3% noted that do possible...

10.15275/ssmj470 article EN cc-by-nc Saratov Journal of Medical Scientific Research 2024-12-31

Objective: to determine the metabolic predictors of maladaptation body water transport workers in Yakutia. Material and methods. A survey 224 male Yakutia was conducted. The adaptive potential (AP) is calculated on basis anthropometric functional indicators body. Biochemical (lactate dehydrogenase (LDH), alkaline phosphatase, creatine phosphokinase, kinase-MV, gamma-glutamyl-transferase, aspartate alanine aminotransferases, glucose, total protein, albumin, triglycerides, urea, creatinine,...

10.15275/ssmj511 article EN cc-by-nc Saratov Journal of Medical Scientific Research 2024-12-31

We investigated levels of spontaneous and mitogen-induced cytokine production (IL-1β, IL-4, IL-6, IL-10 IFNγ) by peripheral blood cells 24 men with unstable angina (UA), including indigenous population (n = 12, Yakuts), a group Russian migrants to the Republic Sakha 12). Activation inflammatory response was revealed in total patients UA, manifesting increase induced pro-inflammatory IL-1β, IL-6 cytokines, IFNγ. As compared healthy individuals, anti-inflammatory IL-4 decreased UA patients,...

10.15789/1563-0625-2012-1-2-143-148 article EN cc-by Medical Immunology (Russia) 2014-07-19

Taking into account the complex maturation process of dendritic cells under culturing conditions, as well available data morphological characteristics at various pathological we find it interesting to assess features cell morphology in oncological patients. The purpose this study was processes breast cancer. In cancer patients, potential for cellular viability and compared healthy individuals is reduced early days cultivation, probably due cytotoxicity chemotherapy radiation therapy time...

10.25789/ymj.2023.83.04 article EN Yakut Medical Journal 2023-09-30

The COVID-19 pandemic has stimulated interest in the development of biotechnology, as well search for new solutions diagnostics immune processes. response immunoglobulins A, M and G had a significant role assessment virus-specific responses. Later, it was understood that comprehensive adaptive immunity processes, is reasonable to study its cellular component. One most affordable methods assessing T cell immunity, which proven itself diagnosis other infectious diseases, such latent...

10.29413/abs.2022-7.5-2.10 article EN cc-by Acta Biomedica Scientifica (East Siberian Biomedical Journal) 2022-12-10

The aim of this study was to identify the prognostically significant anthropometric and bioimpedance indicators for birth a child with high BW in Yakut women.The included 220 women nationality physiological pregnancy childbirth who were examined on third fourth days after delivery.The parameters anthropometry bioimpedancemetry parturient indices newborns investigated.Anthropometric measurements carried out according method V.V. Bunak.Body composition assessed based analysis using ABC-01...

10.21103/article8(3)_oa11 article EN publisher-specific-oa International Journal of Biomedicine 2018-09-15

The data of an experimental study in order to determine the toxic dose positively charged carbon dots (CD) on culture fibroblasts are presented.The used isolated from dermis a healthy adult.The part work consisted assessing morphology depending concentration CD solution.For this purpose, 5 and 1 control groups were formed.In groups, CDsolution was added increasing -from 24.15 120.75 μg/ml.In 5th 6th with solution 96.6 μg/ml, respectively, signs fibroblast destruction (cell fragments)...

10.2991/ahsr.k.220103.019 article EN cc-by-nc Advances in health sciences research/Advances in Health Sciences Research 2022-01-01

<h3>Background</h3> The term seronegative spondyloarthropathies (SpA) is used to define a specific group of disorders with certain common features, an increased incidence HLA-B27, as well negative rheumatoid factor and ANA being among them. association HLA-B27 within the SpA varies significantly, ranging from &lt;50% in psoriatic, enteropathic, inflammatory bowel disease-associated SpA, 80% reactive arthritis, $&gt;&lt;$ 50% enteropathic &gt;95% ankylosing spondilitis. frequency allele also...

10.1136/annrheumdis-2015-eular.6179 article EN Annals of the Rheumatic Diseases 2015-06-01

Для оценки частоты встречаемости патологии шейки матки по данным цитологии и изучения их взаимосвязи с выявлением вируса папилломы человека (ВПЧ) проведен анализ цитологического исследования цервикальных мазков методом жидкостной тестированием на вирус у 92 женщин Алданского района Республики Саха (Якутия). Отмечено преобладание в образцах NILM сравнению интраэпителиальными поражениями матки. Плоскоклеточные интраэпителиальные поражения низкой степени (LSIL) были выявлены 15 случаях...

10.25633/etn.2023.04.07 article RU Естественные и технические науки 2023-04-27

Significance. Numerous studies show an association between low levels of health literacy and poor health. The HLS-EU-Q questionnaire is the most comprehensive one for a complex analysis on population. Men are vulnerable groups in terms purpose study was to assess level among working-age men Yakutsk. Material methods. used adapted version European HLS19 with 47 questions (HLS-EU-Q47). 100 Yakutsk were interviewed. For each respondent, index general calculated using formula: Index = (mean - 1)...

10.21045/2071-5021-2023-69-4-10 article EN Social Aspects of Population Health 2023-01-01
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