A5001572944- Tuberculosis Research and Epidemiology
- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Infectious Diseases and Tuberculosis
- Immunodeficiency and Autoimmune Disorders
- Diagnosis and treatment of tuberculosis
- Hemophilia Treatment and Research
- Asthma and respiratory diseases
- Allergic Rhinitis and Sensitization
- Diet and metabolism studies
- Pneumocystis jirovecii pneumonia detection and treatment
- Long-Term Effects of COVID-19
- Neurological Disorders and Treatments
- Diabetes Management and Research
- Complement system in diseases
- Mycobacterium research and diagnosis
- Sarcoidosis and Beryllium Toxicity Research
- Respiratory viral infections research
- Food Allergy and Anaphylaxis Research
- Human Health and Disease
- Immune responses and vaccinations
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Immune Cell Function and Interaction
- Healthcare Systems and Public Health
- HIV, TB, and STIs Epidemiology
Institute of Immunology and Physiology
2018-2025
Federal Medical-Biological Agency
2018-2025
Sechenov University
2020-2025
Lomonosov Moscow State University
2023-2025
Institute of Immunology
2019-2025
Moscow State University
2024-2025
Ministry of Health of the Russian Federation
2021-2024
Rostov State Medical University
2019-2024
Siberian State Medical University
2019-2024
Moscow Regional Research Institute of Obstetrics and Gynecology
2023
To the Editor, A novel strain of human coronaviruses, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), named by International Committee on Taxonomy Viruses (ICTV),1 has recently emerged and caused an infectious disease. This disease is referred to as "coronavirus 2019" (COVID-19) World Health Organization (WHO).2 The US Centers for Disease Control Prevention (CDC) have proposed that "People with moderate asthma may be at higher risk getting very sick from COVID-19. COVID-19 can...
First cases of new coronaviral infection were reported in Wuhan, Hubei Province, China December 2019. The had caused the death more than 100,000 people worldwide by beginning April 2020. This review analysed characteristics course adults and children, as well capabilities diagnostics, treatment prevention COVID-19. It is possible to allocate groups high risk development severe forms disease (elderly people, with latent tuberculosis infection, adult patients comorbidity) according published...
Горячие точки иммунологии
T and B cell-mediated immunity can be assessed using cell receptor excision circle (TREC) Kappa-deleting recombination (KREC) analysis, respectively, successful implementation of this method requires evaluation the correlation between TREC frequencies subsets as well KREC levels lymphocyte subsets. The aim present study was to evaluate TREC/KREC concentrations T/B at different stages COVID-19.
The COVID-19 pandemic resulted in the cessation of many tuberculosis (TB) support programs and reduced screening coverage for TB worldwide. We propose a model that demonstrates, among other things, how undetected cases affect number future M. (M. tb) infections. analysis official statistics on incidence TB, preventive examination population, patients with bacterial excretion tb Russian Federation from 2008 to 2021 is carried out. desired can be obtained due fluctuation these indicators 2020,...
BackgroundMacrophages (Mф) can be M1/M2 polarized by Th1/2 signals, respectively. M2-like Mф are thought to important in asthma pathogenesis, and M1-like anti-infective immunity, however their roles virus-induced exacerbations unknown. Our objectives were (i) assess polarised phenotype responses rhinovirus (RV) infection vitro (ii) phenotypes healthy subjects people with before during experimental RV vivo.MethodsWe investigated characteristics of polarized/unpolarized human monocyte-derived...
Exploring the link between genetic polymorphisms in folate metabolism genes (MTHFR, MTR, and MTRR) cardiovascular disease (CVD), this study evaluates effect of B vitamin supplements (methylfolate, pyridoxal-5′-phosphate, methylcobalamin) on homocysteine lipid levels, potentially guiding personalized CVD risk management. In a randomized, double-blind, placebo-controlled trial, 54 patients aged 40–75 with elevated moderate LDL-C levels were divided based MTHFR, MTRR polymorphisms. Over six...
The objective of the study: to perform multivariate analysis treatment outcomes in patients with multiple/extensive drug resistant tuberculosis (MDR/XDR TB), including those HIV infection, whose chemotherapy regimens included bedaquiline. Subjects and methods: 70 MDR/XDR TB were enrolled retrospective two-center study, bedaquiline-containing regimen was carried out. Results: performed demonstrated high efficacy good tolerability for even despite continuous ineffective past. prolonged intake...
Abstract Currently, eculizumab is the main effective treatment for paroxysmal nocturnal hemoglobinuria (PNH). The aim of this randomized multicenter noninferiority study was to evaluate efficacy and safety Biosimilar (Elizaria) in comparison with Originator (Soliris) patients PNH. were administered at a dose 600 mg weekly 4 weeks initial stage naive patients, as well maintenance therapy 900 every 2 all patients. primary endpoint comparative assessment hemolytic activity based on area under...