A5047283609- Healthcare Systems and Public Health
- Human Health and Disease
- Nutrition, Genetics, and Disease
- Nutritional Studies and Diet
- Cardiovascular Health and Risk Factors
- Diet, Metabolism, and Disease
- Cervical Cancer and HPV Research
- Thyroid Disorders and Treatments
- Indigenous Studies and Ecology
- Diet and metabolism studies
- Obesity and Health Practices
- Glutathione Transferases and Polymorphisms
- Eicosanoids and Hypertension Pharmacology
- Medical and Agricultural Research Studies
- Liver Disease Diagnosis and Treatment
- Biochemical effects in animals
- Nitric Oxide and Endothelin Effects
- Arctic and Russian Policy Studies
- Birth, Development, and Health
- Effects of Radiation Exposure
- Cardiovascular Disease and Adiposity
- Spaceflight effects on biology
- Technology and Human Factors in Education and Health
- Sodium Intake and Health
- Diverse Scientific Research Studies
Yakut Scientific Research Institute of Agriculture
2021
Academy of Sciences of the Republic of Sakha
2018-2020
North-Eastern Federal University
2018-2020
Institute of Physico-Technical Problems of the North named VP Larionov
2020
Federal Research Center of Fundamental and Translational Medicine
2019
Institute of Biomedical Problems
2015-2018
Lomonosov Moscow State University
2018
State Research Center of the Russian Federation
2015
A one-stage population study was conducted in the working south Yakutia. The 174 people of non-indigenous nationality were examined. Increased uric acid (UA) levels found 27% individuals. association UA level with BMI, OT, lipid spectrum revealed mainly men, systolic blood pressure and glucose women. Abdominal obesity equally frequently recorded both men women, regardless presence or absence hyperuricemia, Logistic regression showed satisfactory information content prognostic significance...
A study was conducted by type "case" (n=29) and "control" (n=69) among the non-indigenous population in south Yakutia with arterial hypertension (AH) presence absence of non-alcoholic fatty liver disease (NAFLD). The groups were comparable age. Patients main group had statistically significantly high systolic blood pressure, average BMI WC values compared patients without NAFLD. In hypertensive combination NAFLD, chance developing obesity is more than 4 times higher to control. Hypertensive...
In order to compare the level of thyroid hormones and antibodies depending on use filtered or untreated water, a survey residents Aldan district South Yakutia was conducted. As result study, more pronounced changes in were revealed women Aldan. The frequency violations low levels T3free, T3total, T4free is noted people who which requires additional comparative study chemical composition purified water consumed by population. Keywords: hormones, drinking
A radiological and medical-biological study of the population Aldan Tommot region South Yakutia, located in zone increased natural radiation, was carried out. The annual individual effective exposure dose to turned out be 2 times higher city (6.22 mSv). contribution radon its decay products 59.5%, - 48.3%. Assessment adaptive potential (AP) circulatory system showed a high percentage occurrence functional stress adaptation mechanisms, especially among residents (86.5%). correlation negative...
The research objective was to study the association of AGT rs699 missense SNP with arterial hypertension (AH) and metabolic risk factors among indigenous people Arctic territory Yakutia.The obtained data show that representatives Yakutia homozygous GG genotype for are characterized by high levels systolic blood pressure.The carriage in AH patients is associated a frequency hypo-HDL cholesterolemia.The patients, compared subjects without AH, higher total cholesterol, LDL-C, triglycerides...
Background:The objective of our research was to study the ethnic-related characteristics lipid and carbohydrate metabolism in indigenous population Yakutia. Methods Results:The conducted under expeditionary conditions North Yakutia (Nizhnekolymsky, Anabarsky, Verkhnekolymsky, Tomponsky, Srednekolymsky districts).In total, 529 people aged between 20 70 years were examined primary health care units.For a comparative analysis, we formed 6 ethnic groups (Yakuts, Evenks, Evens, Dolgans, Chukchi,...
This pilot research was one of the first sociological studies with general questions on genetic testing 300 participants, 75% which were representatives people – Sakha. A quantitative method used: a survey quota sampling (Δ ± 5%), held in February March 2018 City Yakutsk (n = 350).Analysis results have shown that respondents low levels awareness about DNA-testing method: 72.3% "do not know method". Only 18.7% knew since 2000 Medical-Genetic Centre Sakha Republic (Yakutia) conducts DNA...
КОМПЬЮТЕРНЫЕ ПРОГРАММЫ С ОТКРЫТЫМ КОДОМ ДЛЯ АНАЛИЗА МАЗКОВ ШЕЙКИ МАТКИ НА ОНКОЦИТОЛОГИЮКононова И.В. 1 , Софронова С.И. Кириллина М
The research objective was to study the association of ACE gene I/D polymorphism with essential hypertension (EH) and metabolic risk factors among indigenous people northern territory Yakutia.The obtained data show that representatives North Yakutia ID genotype are characterized high levels systolic blood pressure.The carriage DD in EH patients associated a frequency hypercholesterolemia hyper-LDL cholesterolemia.The patients, compared subjects without EH, by higher TC, LDL-C, TG, FPG...
Pathological processes in the pre-reactive period of cold injury have not been studied. The purpose this study is to assess morphological and biochemical parameters blood body patients injury. Material methods . We examined with period. Determined: diene conjugates, malonic dialdehyde, total content low molecular weight antioxidants, superoxide dismutase activity, catalase, glutathione peroxidase, reductase, using a SPECORD 40 spectrophotometer. serum were determined by automator analysis....
Abstract The levels of TBA-active products and antioxidant defense indicators, such as low molecular weight antioxidants (LMWAO from now onward), Vitamin C, catalase, uric acid, were higher in the new population if compared to indigenous people. When comparing biochemical parameters by district type, authors found that inhabitants industrial districts (both indigenous), prooxidant-antioxidant balance (PAB onward) was shifted towards peroxidation. increase original due LMWAO. In it caused...
The research objective was to study the association of AGTR1 rs5186 SNP (the A1166C variant) with essential hypertension among indigenous people Arctic territory Yakutia. Methods and Results: A total 351 participants (224 women 127 men) were examined, including 56 Yakuts, 34 Chukchi, 77 Yukaghirs, 184 Evens. Case (n=168) Control (n=183) groups formed. Allelic variants tested by real-time PCR. We did not find statistically significant differences in frequency distribution alleles genotypes...