A5078445921- Advanced MRI Techniques and Applications
- Advanced Neuroimaging Techniques and Applications
- Functional Brain Connectivity Studies
- Magnetic properties of thin films
- Theoretical and Computational Physics
- NMR spectroscopy and applications
- MRI in cancer diagnosis
- nanoparticles nucleation surface interactions
- Statistical and numerical algorithms
- Time Series Analysis and Forecasting
- Neonatal and fetal brain pathology
- Characterization and Applications of Magnetic Nanoparticles
- Cold Atom Physics and Bose-Einstein Condensates
- Advancements in Solid Oxide Fuel Cells
- Nanocluster Synthesis and Applications
- Fuel Cells and Related Materials
- Magnetic Properties of Alloys
- Nanoporous metals and alloys
- Medical Image Segmentation Techniques
- Chemical and Physical Properties of Materials
- Gold and Silver Nanoparticles Synthesis and Applications
- Radiomics and Machine Learning in Medical Imaging
- Laser-Ablation Synthesis of Nanoparticles
- ZnO doping and properties
- Medical Imaging and Analysis
University of Lausanne
2021-2025
University Hospital of Geneva
2019
Universidade Estadual de Campinas (UNICAMP)
2014
École Polytechnique Fédérale de Lausanne
2006-2011
Institut de Chimie
2011
Abstract Motion during the acquisition of magnetic resonance imaging (MRI) data degrades image quality, hindering our capacity to characterise disease in patient populations. Quality control procedures allow exclusion most affected images from analysis. However, criterion for is difficult determine objectively and can lead a suboptimal compromise between quality sample size. We provide an alternative, data‐driven solution that assigns weights each image, computed index using restricted...
Abstract Despite major progress in understanding the impact of triplicated chromosome 21 on brain and behaviour Down syndrome, our knowledge underlying neurobiology humans is still limited. We sought to address some pertinent questions about drivers structure differences their associations with cognitive function syndrome. To this aim, a pilot magnetic resonance imaging (MRI) study, we monitored anatomy individuals syndrome receiving pulsatile gonadotropin-releasing hormone (GnRH) therapy...
Given the controversy about impact of modifiable risk factors on mood and cognition in ageing, we sought to investigate associations between cardio-vascular risk, mental health, cognitive performance brain anatomy mid- old age. We analyzed a set together with multi-parameter magnetic resonance imaging (MRI) CoLaus|PsyCoLaus cohort (n > 1200). Cardio-vascular was associated differences tissue properties – myelin, free water, iron content regional volumes that interpret context micro-vascular...
Abstract Our knowledge of the mechanisms underlying vulnerability brain’s white matter microstructure to cardiovascular risk factors (CVRFs) is still limited. We used a quantitative magnetic resonance imaging (MRI) protocol in single centre setting investigate cross-sectional association between CVRFs and brain tissue properties tracts large community-dwelling cohort ( n = 1104, age range 46–87 years). Arterial hypertension was associated with lower myelin axonal density MRI indices,...
The room temperature stability of nanometer-sized silver clusters in silica matrices has been investigated by following the temporal evolution their surface plasmon absorption.Ag SiO 2 were prepared either annealing samples doped with atomic or co-deposition pre-formed defined size.Clusters found to be unstable at ambient conditions on a time scale days weeks, independent preparation conditions.The disappearance plasmonic resonance is explained successive oxidation even inside matrix.
Nanoscale structures have been widely studied because their properties differ greatly from bulk counterpart systems, raising both a fundamental and technological interest. Despite the great advances that made, domain still presents challenges. The development of dedicated instrumentation, in particular, is an essential issue since well established techniques used for atomic size macroscopic systems are often not suited study nanoaggregates. In this article, authors present new cluster source...
Abstract Purpose Cardiac pulsation increases the noise level in brain MR images. Maps of transverse relaxation rate R 2 * and magnetic susceptibility (QSM) are particularly affected by cardiac-induced as they computed from gradient-echo data acquired at multiple echo times. Here, we introduce two acquisition strategies to mitigate impact maps QSM. Methods The proposed based on higher near k-space centre. Using a pseudo-spiral sampling trajectory, first strategy allows for specific number...
We describe a new experimental setup for the production of samples metal clusters embedded in matrices stable at ambient conditions. The cluster ions are generated gas phase and codeposited fragmentation-free together with evaporated matrix. Mean sizes range from few to many thousands atoms. For small (n<20) mass selection is possible; larger deposited narrow size distributions. Matrix materials include metals (Cu Ag) oxides such as quartz. performance apparatus well sample...
We have prepared dilute nanostructured magnetic samples by codeposition of preformed cobalt clusters with a narrow size distribution around 40 atoms per cluster in silver matrices. Magnetoresistance measurements are used to derive information about the structure samples. Effects or anisotropy can be neglected our Deviations from simple Langevin-type magnetization observed as function temperature and identified due intercluster interactions. Pairwise magnetostatic indirect exchange...
We present a novel approach that allows the estimation of morphological features axonal fibers from data acquired in vivo humans. This assessment white matter microscopic properties non-invasively with improved specificity. The proposed is based on biophysical model Magnetic Resonance Imaging (MRI) and conduction velocity estimates obtained Electroencephalography (EEG). In tract interest, these depend (1) distribution radius [P(r)] (2) g-ratio individual axons compose this [g(r)]. P(r)...
Cardiac pulsation increases the noise level in brain maps of transverse relaxation rate R2 *. Cardiac-induced is challenging to mitigate during acquisition * mapping data because its characteristics are unknown. In this work, we aim characterize cardiac-induced MRI parameter *.We designed a sampling strategy acquire multi-echo 3D 12 intervals cardiac cycle, monitored with fingertip pulse-oximeter. We measured amplitude and assessed effect on computed across echoes. The area k-space that...
Consistent noise variance across data points (i.e. homoscedasticity) is required to ensure the validity of statistical analyses MRI conducted using linear regression methods. However, head motion leads degradation image quality, introducing heteroscedasticity into ordinary-least square analyses.The recently introduced QUIQI method restores homoscedasticity by means weighted least in which weights, specific for each dataset an analysis, are computed from index motion-induced quality...
Efforts at EPFL to obtain translationally cold neutral molecules are described. Active deceleration of polar is performed by confining the in moving three-dimensional electrostatic traps, and appropriately choosing velocity those traps. Alternatively, can be obtained filtering. Here, not changed, but instead extracted from a thermal sample using competition between force centrifugal inside bent guide for molecules.
Anode supported thin film electrolytes are nowadays the mostly used cells in SOFC area. Unfortunately they dramatically damaged if re-oxidation occurs anode chamber. In order to overcome this problem, Fiaxell Sàrl developed an half-cell, 2R-Cell™, that provides robustness and reliability upon multiple thermo- redox-cycles. Here we report on performances stability of 2R-Cell™ tested with different cathode materials: LSM, LSC in-situ LSC-GDC. All presented measurements have been performed test...
Abstract Motion during the acquisition of magnetic resonance imaging (MRI) data degrades image quality, hindering our capacity to characterize disease in patient populations. Quality control procedures allow exclusion most affected images from analysis. However, criterion for is difficult determine objectively and can lead a suboptimal compromise between quality sample size. We provide an alternative, data-driven solution that assigns weights each image, computed index using restricted...
The aim of this thesis is to get a deeper understanding magnetic properties small clusters when they are embedded in host material. study was motivated by the observation very peculiar that present gas phase or deposited on substrate. intriguing perspective those would be preserved solid state sample could used for technological applications. Preformed and well characterized as building blocks produce nanostructured films which material order preserve them from chemical thermal degradation...
Abstract Consistent noise variance across data points (i.e. homoscedasticity) is required to ensure the validity of statistical analyses MRI conducted using linear regression methods. However, head motion leads degradation image quality, introducing heteroscedasticity into ordinary-least square analyses. The recently introduced QUIQI method restores homoscedasticity by means weighted least in which weights, specific for each dataset an analysis, are computed from index motion-induced quality...