A5069496608- Antibiotic Resistance in Bacteria
- Bacteriophages and microbial interactions
- Bacterial biofilms and quorum sensing
- Microplastics and Plastic Pollution
- vaccines and immunoinformatics approaches
- Antibiotics Pharmacokinetics and Efficacy
- Circular RNAs in diseases
- MicroRNA in disease regulation
- Cancer therapeutics and mechanisms
- Protein Structure and Dynamics
- Cervical Cancer and HPV Research
- Machine Learning in Bioinformatics
- Gut microbiota and health
- Reproductive tract infections research
- Antimicrobial Resistance in Staphylococcus
- Trace Elements in Health
- Nanoparticle-Based Drug Delivery
- Graphene and Nanomaterials Applications
- Genomics and Phylogenetic Studies
- Antibiotic Use and Resistance
- Drug Transport and Resistance Mechanisms
- Gold and Silver Nanoparticles Synthesis and Applications
- Immunotherapy and Immune Responses
- Berberine and alkaloids research
- Vibrio bacteria research studies
Vellore Institute of Technology University
2023-2025
Christian Medical College & Hospital
2022-2023
Microbial Dysbiosis is associated with the etiology and pathogenesis of diseases. The studies on vaginal microbiome in cervical cancer are essential to discern cause effect condition. present study characterizes microbial involved developing cancer. Relative species abundance assessment identified Firmicutes, Actinobacteria, Proteobacteria dominating phylum level. A significant increase Lactobacillus iners Prevotella timonensis at level revealed its pathogenic influence progression....
Alzheimer disease (AD) is a leading cause of dementia in elderly patients who continue to live between 3 and 11 years diagnosis. A steep rise AD incidents observed the population East-Asian countries. The progresses through several changes, including memory loss, behavioural issues, cognitive impairment. etiology hard determine because its complex nature. whole exome sequences late-onset (LOAD) Korean origin are investigated identify rare genetic variants that may influence disorder....
The association of suspended particulate matter with micro contaminants presents a significant threat to human health. effects airborne and microplastics (MPs) on indoor outdoor atmospheric conditions remain ambiguous. Furthermore, our understanding the toxicological impacts contaminated aquatic organisms is limited. This study aims explore pollutants when interacting MPs, focusing physiology growth Artemia salina. data indicates that significantly affect hatching success Artemia, especially...
Investigates the synergistic impacts of particulate matter and nanoplastics on vitality longevity Artemia salina , emphasizing potential implications for environmental sustainability ecological balance.
Abstract Metallo‐β‐lactamases (MBLs), enzymes of class B, employ zinc ions to degrade β‐lactam antibiotics such as penicillins, cephalosporins, carbapenems, and cephamycins. Carbapenem‐resistant Acinetobacter baumannii (CRAB) is linked the existence carbapenemase oxacillinase MBL. The most prevalent resistance mechanisms include imipenemases (IMP), verona integron‐encoded MBL, New Delhi MBL‐1. effectiveness current against MBL enzyme limited due presence metal ions, underscoring need for new...
The increasing prevalence of antimicrobial resistance, particularly in Gram-negative bacteria such as Acinetobacter baumannii, demands new antibiotics existing ones become increasingly ineffective. production lipopolysaccharide (LPS) is vital bacteria, making it a promising target for antibiotic development. This study focuses on discovering targeting the early-stage LpxA, LpxC and LpxH enzymes. These are crucial to lipid A biosynthesis Raetz pathway bacterial survival virulence. LpxA...
Abstract Carbapenem‐resistant Acinetobacter baumannii , a predominant nosocomial pathogen in hospitals of intensive care units, is associated with bacteremia and ventilator‐associated pneumonia high‐risk mortality rate. To increase the effectiveness β‐lactam (BL) antibiotics, use β‐lactamase inhibitors (BLI) acts as booster when given combination BL antibiotics. this aspect, we selected antibiotics cefiderocol, cefepime, non‐BL antibiotic eravacycline, BLI durlobactam, avibactam, enhancer...
Abstract Persistent antibiotic use results in the rise of antimicrobial resistance with limited or no choice for multidrug resistant (MDR) and extensively drug (XDR) bacteria. This necessitates a need alternative therapy to effectively combat clinical pathogens that are last resort antibiotics. The study investigates hospital sewage as potential source bacteriophages control MDR/XDR bacterial pathogens. 81 samples were screened phages against selected 10 isolated A. baumannii , 5 K....