A5100746581- Heavy Metal Exposure and Toxicity
- Esophageal Cancer Research and Treatment
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Trace Elements in Health
- Esophageal and GI Pathology
- Nanoparticles: synthesis and applications
- Gastric Cancer Management and Outcomes
- Climate Change and Health Impacts
- Machine Learning in Materials Science
- Fetal and Pediatric Neurological Disorders
- Inflammation biomarkers and pathways
- Nanoplatforms for cancer theranostics
- Testicular diseases and treatments
- Zebrafish Biomedical Research Applications
- Winter Sports Injuries and Performance
- Sarcoma Diagnosis and Treatment
- Circular RNAs in diseases
- Cerebrospinal fluid and hydrocephalus
- Phagocytosis and Immune Regulation
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Intracerebral and Subarachnoid Hemorrhage Research
- Graphene and Nanomaterials Applications
- MRI in cancer diagnosis
- Thermoregulation and physiological responses
Qingdao University
2023-2025
Shenzhen Children's Hospital
2025
Shandong First Medical University
2020-2023
Jinan University
2023
University of Jinan
2020
Zhengzhou University
2014-2016
Henan Provincial People's Hospital
2015-2016
The Central Hospital of Shaoyang
2009
Tris(2-chloroethyl) phosphate (TCEP), a prevalent organophosphorus flame retardant, has been identified in various environmental matrices and human blood samples, provoking alarm regarding its hematological toxicity, subject that not thoroughly investigated. Red cells (RBCs), or erythrocytes, are the predominant cell type peripheral crucial for maintenance of physiological health. This investigation employed oral gavage to examine effects TCEP exposure on erythrocyte counts mice clarify...
Abstract Perfluorinated compounds (PFCs) is a well-recognized environmental risk factor for atherosclerosis. However, corresponding atherogenic in susceptible populations consuming high-fat diets (HFD) remain unclear. Here, we found that perfluorooctane sulfonic acid (PFOS), canonical PFCs, elevated the mice fed with HFD, which was characterized by an increased number of pro-inflammatory phenotype macrophages. We also macrophages exhibited metabolic reprogramming to glycolysis, attributed...
Silica nanoparticles (SiNPs) have been widely used in electronics, chemistry, and biomedicine. Human exposure to SiNPs possible health effects attracted much attention. The potential cardiovascular toxicity of their related mechanisms are still unclear. Therefore, this study, we investigated the toxic on human umbilical vein endothelial cells (HUVECs). We found that could induce HUVECs ferroptosis. results showed level intracellular divalent iron lipid peroxidation increased, mitochondrial...
The use of silica nanoparticles (SiNPs) is increasing in popularity; however, the emissions released during manufacturing, and disposal stages potentially harm environment. SiNPs can enter body cause cardiac toxicity indirectly or directly. However, toxicological data on cells vitro, detailed molecular mechanisms by which damage caused remain unclear. In present study, oxidative stress-mediated apoptosis cytotoxicity induced H9c2 were examined. used to explore treating with 0, 25, 50, 100,...
Abstract Silica nanoparticles (SiNPs) as one of the most productive nano‐powder, has been extensively applied in various fields. There increasing concern about adverse effects SiNPs on health ecological organisms and human. The potential cardiovascular toxicity involved mechanisms remain elusive. Hence, this study, we investigated (60 nm) explored underlying using H9c2 cardiomyocytes. Results showed that induced oxidative stress activated Nrf2/HO‐1 antioxidant pathway. Autophagy was also by...
To prospectively determine the feasibility of T2 -mapping magnetic resonance imaging (MRI) to quantitatively describe signal characteristics normal esophageal wall and assess depth invasion by carcinoma at 3.0T.Thirty-two patient specimens, each having foci carcinoma, were studied using 3.0T MR. Freehand regions interest placed measure value layers compared with carcinoma. Three independent readers reviewed MR images evaluate invasion; when three radiologists could not fully agree other,...
Abstract High-resolution magnetic resonance (MR) images clearly depict the normal oesophageal wall as consisting of eight layers, which correlates well with histopathological findings. In 56 (91.8%) 61 lesions, depth invasion determined through MR imaging was consistent staging (r = 0.975, P < 0.001). The sensitivity, specificity and accuracy for mucosa were 71.4%, 98.1%, 95.1%, respectively, corresponding values submucosa 82.4%, 95.5%, 91.8%; muscularis propria, 100%, 95.7%, 96.7%,...
Abstract Magnetite nanoparticles (MNPs) have been extensively detected in the atmospheric environment and implicated as a prominent threat to atherosclerosis, chronic vascular inflammatory disease. Due globalization economic development, dramatic shift diet from traditional high‐fat dietary patterns aggravated atherosclerosis progression induced by environmental factors. However, limited knowledge is available regarding risks underlying mechanisms of airborne MNPs high‐risk populations with...
<p indent="0mm">The accelerated research and development of high-density hydrogen-storage materials are critical to the transition energy economy realization carbon peaking neutrality goals. The data-driven paradigm-integrated high-throughput calculations, database, machine learning is appealing accelerate new material development. Due their complex compositions, structures morphologies, on still limited, a database comprehensive properties necessary be established. Herein, we show our...
Objective To explore the value of 3.0 T high-resolution MR imaging in diagnosis esophageal carcinoma stage T1a,T1b and T2. Methods Thirty four specimens were obtained from 34 consecutive patients, who had proven by gastroscopy biopsy preoperatively, postoperative scanned MRI as pathological T1a, T1b T2. All with within 30 minutes postoperatively followed histopathological examinations immediately. A pathologist was blind to findings identified normal layers invasion staging. The...
Objective To explore the imaging characteristics of seminomas and nonseminomatous germ cell tumors (NSGCT) its pathological foundation. Methods CT MR manifestations in 25 cases testicular proved by examinations were analyzed retrospectively. All divided into group (12 cases) NSGCT (13 cases). In group, 5 examined CT 4 those also had contrast enhanced CT. Seven MRI dynamic MRI. plain which two CT, eight or (morphology, density intensity, enhancement) both groups byFisher...