- Hepatitis C virus research
- Liver Disease Diagnosis and Treatment
- Hepatitis B Virus Studies
- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Liver Disease and Transplantation
- Diagnosis and treatment of tuberculosis
- Gastric Cancer Management and Outcomes
- Spectroscopy Techniques in Biomedical and Chemical Research
- Immunodeficiency and Autoimmune Disorders
- Microscopic Colitis
- HIV/AIDS drug development and treatment
- Bariatric Surgery and Outcomes
- Psoriasis: Treatment and Pathogenesis
- Long-Term Effects of COVID-19
- Liver Diseases and Immunity
- Esophageal and GI Pathology
- Blood groups and transfusion
- Autoimmune Bullous Skin Diseases
- Inflammatory Bowel Disease
Cairo University
2018-2024
Progression of recurrent hepatitis C is accelerated in liver transplant (LT) recipients. Direct-acting antivirals (DAAs) have recently emerged as a promising therapeutic regimen for the treatment virus infection. Rates sustained virological response (SVR) drastically improved since introduction DAAs. The aim to elucidate changes stiffness measurement (LSM) by transient elastography (TE) well acoustic radiation force impulse (ARFI) and fibrosis scores after DAA LT recipients with recurrence....
Biologic drugs are therapeutic modalities designed to inhibit specific cytokine signaling pathways. The introduction of these in the management autoimmune diseases has dramatically changed treatment paradigm chronic systemic immune-mediated inflammatory disorders. However, despite their overall acceptable safety profiles, paradoxical reactions have been reported some real-life cases including case studies and clinical trials. In this study, we report a patient with Crohn's disease who...
Hepatitis C virus (HCV) is a major health problem in Egypt, with high prevalence of genotype 4.This study aimed to evaluate the safety and efficacy generic sofosbuvir (SOF) plus daclatasvir (DAC) or without ribavirin treatment Egyptian chronic HCV patients compared use brand drugs.An observational that included 234 was carried out. Patients were classified into two groups: group A (101 patients) received SOF 400 mg DAC 60 B (134 for 12 weeks. The end point sustained virological response at...
Abstract Background Inflammatory bowel disease ( IBD) is widespread and rapidly rising in developing countries. It remains a significant issue Western culture with prevalence of more than 0.3%. Symptom control has been the only focus treatment before discovery that many individuals IBD continue to have activity even absence clinical symptoms. Therefore, goals now include establishing remission, steroid-free mucosal healing, which may eventually be complemented by transmural healing...
Introduction Interferon-based therapies against the hepatitis C virus had a poor adherence profile. On other hand, new direct-acting antivirals (DAAs) are orally administered medications, show high efficacy in addition to safety Therefore, this treatment is expected improve. Assessment for mandatory assess feasibility of achieving viral elimination. Aim The study aims rate and causes non-adherence Egyptian patients who received interferon-free regimens. Methods Retrospective data analysis...
Background: The researchers conducted the current study to explore knowledge and satisfaction with Hepatitis C Healthy Lives Initiative among a sample of Egyptians.Methods: An exploratory cross-sectional was carried out 1,193 clients attending HCV screening sites via consecutive sampling technique. A structured interview questionnaire used, including three sections: sociodemographic characteristics, hepatitis program, HCV-related knowledge.Results: Our results demonstrated that approximately...
Dear Sir,Coronavirus disease-19 (COVID-19) is a pandemic disease which caused by SARS-CoV2 virus. It one of the biggest single-stranded positive-sense RNA viruses. dependent RNA...
Among 21 cases of COVID-19 infection in our center, median age at diagnosis was 40 ± 12.8 years, and the interval since transplantation 4.75 years. Fever (100%) radiographic abnormalities form unilateral or bilateral/multifocal consolidations (80%) were most common presentations. Macrolide's antibiotics used 75% patient.95% improved 4.6% showed mortality, reduction stoppage current immunosuppressives only 19%.
Background: HBV reactivation is a preventable disease with high incidence among immunosuppressed.This can be attributed to either virus widespread in the community or an inadequate assessment of status prior start drug therapy. Materials and strategies:A prospective cohort study included 200 patients various autoimmune diseases initiation their immunosuppressives, 1 year follow up.Baseline liver biochemicals virology were recorded for all patients, they arranged into 4 groups (Group A,...