A5102001979- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Urologic and reproductive health conditions
- Testicular diseases and treatments
- Genital Health and Disease
- Bladder and Urothelial Cancer Treatments
- Renal cell carcinoma treatment
- COVID-19 epidemiological studies
- Transportation and Mobility Innovations
- Primary Care and Health Outcomes
- Transportation Planning and Optimization
- CAR-T cell therapy research
- Color Science and Applications
- Surgical Simulation and Training
- Health Systems, Economic Evaluations, Quality of Life
- Psychological Well-being and Life Satisfaction
- Advanced Causal Inference Techniques
- Esophageal Cancer Research and Treatment
- T-cell and B-cell Immunology
- Family Dynamics and Relationships
- Occupational Health and Safety Research
- Telemedicine and Telehealth Implementation
- Male Reproductive Health Studies
- COVID-19 and Mental Health
- Urinary and Genital Oncology Studies
University of Chinese Academy of Sciences
2024
Fujian Provincial Hospital
2017-2024
Fujian Medical University
2019-2024
Weatherford College
2021
Xi'an Jiaotong University
2021
Chinese Center For Disease Control and Prevention
2020
National Institute for Communicable Disease Control and Prevention
2020
Stanford University
2020
Second Xiangya Hospital of Central South University
2020
Central South University
2020
In December 2019, novel coronavirus pneumonia epidemic occurred in Wuhan, Hubei Province, and spread rapidly across the country. early stages of epidemic, China adopted containment strategy implemented a series core measures around this strategic point, including social mobilization, strengthening case isolation close contacts tracking management, blocking areas traffic control to reduce personnel movements increase distance, environmental personal protection, with view controlling as soon...
This study conceptualizes parental migration as a dynamic family process that exposes children to absence and instability. Using detailed histories, this identifies the left‐behind trajectories of rural Chinese throughout childhood (age 1–12) examines impact on psychological well‐being ( N = 3,961). Results indicate heterogeneity in children’s experience migration, which is characterized by both persistence (prolonged absence) instability (repeated migration). A quarter experienced prolonged...
Our study aims to assess the effectiveness and safety profile of Disitamab Vedotin (DV, RC48-ADC), an innovative humanized anti-HER2 antibody conjugated with tubulin-disrupting antimitotic drug monomethyl auristatin E (MMAE) via a cleavable peptide linker. This treatment combined immune checkpoint inhibitors as part bladder sparing approach for selected patients suffering from locally advanced urothelial carcinoma.
Abstract The aim of the study was to explore relation various factors with unprotected anal intercourse (UAI) and provide some insight for HIV intervention on Chinese men who have sex (MSM). current cross-sectional recruited 365 MSM in Dalian, China. More than half respondents (117 respondents, 51.8% sample) had engaged UAI. multivariable logistic regression model suggested that poorer mental health (AOR: 7.16; 95% CI: 3.14–16.31), self-stigma 1.53; 1.00–2.34), experience(s) physical abuse...
The present study uses data from a 2020 survey conducted in Shaanxi Province during the COVID-19 outbreak to examine family resources and psychological well-being of four major groups Chinese children (urban, migrant, rural nonmigrant, left-behind children). results highlight complex ways which intersect with pandemic affect these different children. Family economic have generally declined across all groups, but suffered most severe shock. However, parent–child relationships for improved...
Prostate cancer is one of the most common malignancies in men. Protein ubiquitination an important mechanism for regulating protein activity and level vivo. We aimed to study SEPT6 UBC action prostate identify new targets.The ubiquitin-protein ubiquitin coding gene UBA52, UBA80, UBB, expressions were detected clinical tissues cells. Overexpression knockdown performed DU145 Cell Counting Kit 8 (CCK-8) assay was detect cell proliferation. cycle at 24 h by flow cytometry. Clonal formation used...
This study applied a partial least squares structural equation model (PLS-SEM) to examine how perceived waiting time may be interactively influenced by observed time, station amenities, trip contexts, and respondent characteristics. The estimation results of the inner indicated that, except for some direct measures (such as increasing departure frequency), creating good environment helping passengers smartly use public transport both have positive effects on reducing perceptions. From outer...
Although prostate biopsy is the gold standard for diagnosis of cancer, it also leads to high incidence negative biopsies and clinically low-risk cancer subsequent overtreatment. It remains an unmet need discover new biomarkers in order defer unnecessary clinical practice. In this study, we described a method, LBXexo score, measure urine exosomal PCA3/PRAC expression from non-DRE as noninvasive improve detection rate Chinese population with low serum PSA level. First-voided samples were...
Objectives: To evaluate the economic implications of payments based on Chinese diagnosis-related groups for critically ill patients in ICUs terms total hospital expenditure, out-of-pocket payments, and length stay. Design: A pre-post comparison patient cohorts admitted to 1 year before after group reform was undertaken. Demographic characteristics, clinical data, medical expenditures were collated from a health insurance database. Setting: Twenty-two public hospitals Sanming, Southern China....
Ketamine is a glutamate N-methyl D-aspartate receptor antagonist and an anaesthetic agent that has been effectively used to treat depression. However, ketamine also increasingly for recreational purposes. The dissociative side-effects of use, such as hallucinations, are the reason abuse. Additionally, long-term abuse highly associated with liver-gallbladder urinary symptoms. present study reports case 28-year-old young male adult 8-year history daily inhalation ketamine. We investigated...
Whether neoadjuvant therapy confers a survival benefit in advanced prostate cancer (PCa) remains uncertain. The primary endpoints of previous retrospective and phase II clinical studies that used therapy, including androgen deprivation combined with new-generation receptor signaling inhibitors or chemotherapy, were pathological downstaging, progression-free survival, prostate-specific antigen relief, local symptom improvement. To the best our knowledge, no have explored efficacy safety...
To examine whether scrotoscopy could be used to diagnose testicular rupture (TR) with accuracy.This retrospective study included all patients receiving followed by immediate open exploration (OE) for suspected TR at two Chinese tertiary care centers between March 2014 and 2018.Fifteen of having were included. was considered in 8 (8/15) via emergency scrotal ultrasound (ESU) examination. Of these patients, 6 cases as well 3 other cases, a total 9 (9/15) confirmed OE; the remaining (6/15)...
This population-based propensity score-matching study aimed to investigate the survival outcomes of patients with biopsy- and transurethral resection prostate (TURP)-diagnosed cancer (PC). We obtained data from Surveillance, Epidemiology End Results (SEER) database, PC diagnosed by biopsy TURP 1975 2019 were enrolled. Cohort baseline-matched using a (PSM) study. Compared biopsy-confirmed (BPC) patients, cancer-specific mortality (CSM) overall (OM) in (TPC) analyzed. A total 26,027 cases for...
Coal remains a crucial component of China’s energy supply, with production exceeding half the global output in 2023. Despite safety improvements, fatality rate coal mining rose significantly, underscoring ongoing challenges. A total 174 mine explosion investigation reports from China between 2000 and 2024 were analyzed, extracting text related to coordination failures. The texts categorized by time region, creating two temporal datasets (2000–2018 2019–2024) six regional (Northeast, East,...
Objective This study aimed to evaluate the awareness rate of prostate-specific antigen (PSA) among general public in China and provide data about prostate cancer (PCa) for related scientific research. Methods A cross-sectional survey PSA was conducted multiple regional populations using an online questionnaire. The questionnaire included basic information, knowledge PCa, application PSA, future expectations toward applying screening clinical practice. applied methods Pearson chi-square...
To compare the middle-term efficacy and safety results between scrotoscope-assisted (SA) minimally invasive excision traditional open (OE) for treatment of epididymal mass.A total 253 males with surgery mass from 2012 to 2018 were included in this retrospective study. Patients divided into two groups: OE group SA group. Patient demographics intraoperative postoperative outcomes obtained compared these groups.About 174 patients (68.8%) underwent SA, other 79 (31.2%) OE. Demographic data...
Abstract Clear cell adenocarcinoma of the prostate (CCPC) is a rare entity compared to acinar carcinoma (APC). The survival rate and prognostic factors CCPC are still unclear deserve further study. We downloaded data on cancer from Surveillance, Epidemiology, End Results database for 1975–2019. After inclusion exclusion criteria, we APC analyzed cancer-specific mortality (CSM) overall (OM) in patients risk using propensity score matching (PSM) study multivariate Cox regression. included...