Lung cancer is one of the leading causes death, and mortality rates have steadily been increasing. Recently, several studies were conducted to develop novel, physiologically active compounds from medicinal plant extracts. Several plant-derived extracts molecules regulate inhibit signaling associated with growth proliferation cells. Euryale ferox salisb a that effective against different types cancers. In this study, we investigated apoptotic effects E. extract (ESE) in A549 lung cells,...

Barley sprouts are known to have several effective physiological activities. In this study, the anti-obesity effect of a barley sprout hot water extract (BSE) was confirmed. Saponarin quantitatively analyzed in BSE using HPLC, and inhibitory on 3T3-L1 pre-adipocyte differentiation into adipocytes confirmed by Oil Red O staining, TG assay, Western blotting. addition, adipocyte growth through glucose uptake lipolysis adipocytes. C57/BL/6N mice were induced obesity with high-fat diet,...

Despite advances in medical treatments, the proportion of population suffering from alopecia is increasing, creating a need for new treatments to control hair loss and prevent balding. Treatments based on plant-derived compounds could potentially loss. Human follicle dermal papilla (HDP) cells, type specialized fibroblast bulb, play an essential role controlling growth conditions such as androgenic alopecia. We examined effect Bacillus/Trapa japonica fruit ferment filtrate extracts (TJFs)...

Scaphium affine ethanol extracts (SAE) is a species that has been shown to contain various physiological effects; however, its anticancer effects have yet be revealed. We qualitatively evaluated β-sitosterol in SAE through high-performance liquid chromatography (HPLC). The cytotoxicity HCT116 and HT29 colorectal cancer cells CCD841 normal colon was confirmed WST-1 assays. Selective observed cells, with greater demonstrated the cell line. As such, line selected for subsequent experiments....

Abstract The Trapa japonica fruit is a natural plant growing in ponds with its roots the mud. It has long been used as home remedy for many diseases; however, major problem this kind of extract multicomponents-multitargets diseases. Such problems make it difficult to identify mechanism action. Another quality control and consistency. aim research was isolate single bioactive compound (peptide) derived from fruit. conducted various experimental techniques, such fermentation liquid...

The dermis, composed predominantly of dermal fibroblasts and extracellular matrix (ECM), consists fibrous proteins such as collagen elastin is associated with wrinkle formation elasticity. As the major constituent matrix, strengthens skin, enhances its elasticity protects it from external factors, ultraviolet (UV) rays, skin inflammation, intracellular metabolites, aging.Economic growth long-life expectancy have increased interest in beauty, extensive studies conducted to evaluate anti-aging...

Cheongchunchal (CE) is a developed crop more highly enriched in cyanidin-3-O-glucoside chloride (anthocyanin) than conventional waxy corn. Anthocyanin has been proven to have anti-oxidant, anti-inflammatory, anti-obesity, and anti-cancer effects. In this study, using high-performance liquid chromatography (HPLC), was confirmed contain 8.99 mg/g anthocyanin. The inhibitory effect of an ethanol extract on adipocyte differentiation demonstrated Oil Red O staining triglyceride assay. By...

Cancer metastasis is directly related to the survival rate of cancer patients. Although proceeds by movement cells, it fundamentally caused its resistance anoikis, a mechanism apoptosis loss adhesion cells. Therefore, was found that inhibiting migration and reducing anoikis are important for suppression, natural compounds can effectively control it. Among them, Ribes fasciculatum, which has been used as medicinal plant, confirmed have anticancer potential, experiments were conducted prove...

Cinnamomum camphora is known as a tree that has been used in traditional medicine and food. However, its biological activities cancer have not yet clearly investigated. In this study, we investigate the anti-cancer effects of ethanol extract on two kinds human colon cell lines (HCT 116 HT-29). previous about 50% cells p53 mutations. Therefore, with different gene mutation status are able to verify more accurately. it conducted several experiments prove through apoptosis autophagy. It...

Collagen is decomposed by MMP-1, an enzyme induced transcription factor activator protein 1 (AP-1) and matrix metalloproteinase-9 (MMP-9). Action of MMPs in inflammatory response promotes cell movement secretion, resulting wrinkles on the skin. After using Bacillus sp. fermentation system water, Artemisia vulgaris was fermented to prepare different solvent fractions dichloromethane, hex ane, n-butanol, ethyl acetate. These were used assess their effects survival, wound healing, MMP-1/MMP-9...

Obesity is caused by a variety of reasons, such as diet, genetics, and environmental factors. Here the effect Barley sprout extract on differentiation 3T3-L1 expression adipogenesis was studied. MTT assay for cell toxicity performed found to be non-toxic at 3T3-L1, with survival rate 90% or higher in all concentrations. The results oil red O assay, after inducing treating fat formation insulin, dexamethasone, IBMX powder-inducing substances showed that inhibited formation. triglyceride...

Rumex japonicus Houttuyn (RJE) is the root of curled dock. Previous studies have demonstrated anti-oxidant and anti-inflammatory effects RJE. Based on these studies, we conducted an experiment to prove RJE’s anticancer effects. A 3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide (MTT) assay confirmed a decrease in viability HCT116 colon cancer cells cytotoxicity. We observed that rate cell cycle arrest increased according RJE concentration. Western blotting presence apoptotic...

Rumex japonicus Houttuyn is known for its antiinflammatory and anti-microbial effects. In this study, we determined the effects of ethanol extract (RJHE) on anti-obesity activities in 3T3-L1 preadipocytes. vitro experiments to prevent obesity improve effects, research using preadipocytes essential, it also distinctly represents morphologic molecular changes. Our results showed that RJHE decreased differentiation preadipocytesusing oil red O staining through decreasing lipid droplet had no...