A5087190335- Cerebrovascular and Carotid Artery Diseases
- Neurological Disorders and Treatments
- Acute Ischemic Stroke Management
- Traumatic Brain Injury and Neurovascular Disturbances
- Intracranial Aneurysms: Treatment and Complications
- Wound Healing and Treatments
- Atrial Fibrillation Management and Outcomes
- Mesenchymal stem cell research
- Diagnosis and Treatment of Venous Diseases
- Peripheral Artery Disease Management
- Pain Management and Treatment
- Laser Applications in Dentistry and Medicine
- Venous Thromboembolism Diagnosis and Management
- Neurological Disease Mechanisms and Treatments
- Diabetic Foot Ulcer Assessment and Management
- Cardiovascular Health and Disease Prevention
- Tissue Engineering and Regenerative Medicine
National Academy of Medical Sciences of Ukraine
2019-2024
Kharkiv National Medical University
2024
Aim. To experimentally study the effect of light different ranges on proliferation and migration mesenchymal stem cells human MSCs to select its optimal parameters for treatment. Materials methods. The experiment was conducted in vitro 260 cultures isolated from peripheral blood by magnetic separation. Cells were treated with pulsed LED light: 475 nm, 516 635 nm or left unstimulated. All devices had a peak radiation intensity 80 mW/cm2. average reached 40 Irradiation carried out at room...
Objective. To study the effectiveness of technology combined use negative pressure wound therapy and tissue in different phases process patients with diabetes mellitus. Materials methods. We analysed results treatment 18 type II mellitus grade IV Fontaine limb ischemia at Department Acute Vascular Diseases Zaitsev Institute General Emergency Surgery National Academy Medical Sciences Ukraine 2022–2024. Diagnostic angiography by Seldinger endovascular or hybrid revascularisation were...
Objective. To determine the treatment tactics for varicose dilation of veins, complicated by thrombosis subcutaneous veins and shin deep using miniinvasive methods.
 Маterals methods. The results in IGUS named after V. Т. Zaytsev NAMS Ukraine 2015 - 2017 yrs 80 patients, suffering varicothrombophlebitis, were analyzed. patients divided into two groups. In Group I 38 varicothrombophlebitis and/or vein (DVT), included, who treated accordance to algorithm proposed. II 42 with same...
The aim — to analyze the results of complex treatment patients with carotid artery stenoses and abnormalities organ vision.Materials methods. analysis was conducted examination 27 changes in visual fields lesions arteries V. T. Zaitsev Institute General Emergency Surgery Medical Center «Ophthalmika» during 2017—2018 years. were divided into 2 groups: I group 16 whom defeat required only conservative therapy II 11 hemodynamically significant stenosis or an unstable plaque that underwent...
Summary. An aim of work is an analysis results inspection and treatment patients with the hemodynamically meaningful defeat carotids in combination pathology other organs systems. Materials methods. The are analysed 187 by stenosis SI «Zaycev V.T. IGUS NAMSU» from 2015 for 2018 on a background forthcoming surgical chronic ischemia lower limbs, ischemic heart or gastrointestinal tract trouble. Patients divided into 3 groups. first group was made limbs 2-Д degree - 167 patients. 7 entered...
Aim. To define tactics of treatment patients with infecting synthetic patch after carotid endarterectomia(CEA).
 Materials and methods. As a result 123 hemodynamically meaningful stenosises carotids and/or presence embolic plate in SI «Zaycev V.T. IGUS NAMSU» from 2014 for 2018 51 CEA was executed seaming patch. In 5 cases autove used as patch, at 46 were rule, this group entered by extensive stenosis (more than 2 cm) - 33 patients, insufficient retrograde pressure neurological deficit...
The results of examination and treatment by carotid endarterectomy method in 23 patients with atrial fibrillation lesions the arteries State Institution «V.T. Zaitsev IGES NAMSU» from 2017 to 2019. Antiplatelet agents (aspirin were prescribed 20 patients, clopidogrel 3 patients) due presence cardiovascular disease previous myocardial infarction. No patient was found have impaired cerebral circulation postoperative period. Tension hematoma diagnosed two bleeding soft tissues, which required...
The results of a comprehensive examination and surgical treatment 230 patients with atherosclerotic lesions the carotid arteries were analyzed. study included symptomatic stenosis internal artery (ICA) (more than 50 %), asymptomatic ICA 70 unstable plaque, visual impairment. To assess severity neurological deficits, degree recovery functions, scoring system various clinical parameters was performed using scale stroke National Institutes Health (NIHSS) evaluation recommendations. Patients...
54 patients with acute stroke were examined and treated: 12 treated by thrombolytic therapy and/or thrombectomy, 22 endarterectomy from the internal carotid artery, 20 anticoagulant, nootropic antiplatelet therapy. Collateral blood circulation of vessels foci cerebral ischemia in ischemic all to select a treatment method. The effect collateral recanalization arteries on outcome was analyzed. According such parameters neuroimaging as large nucleus poor collaterals, 25 out did not respond...
Aim. To define risks and complications for patients with the sharp ischemia of lower extremities in period stroke after reconstructive surgical treatment decline amount amputations violations cerebral circulation blood postoperative period.Materials methods. In 2015–2019 based on Department Acute Diseases Vessels State Institution «ICUS by. VT Zaitsev NAMNU »we operated 31 acute during ischemic (namely, within 3–4 weeks neurological manifestations). The mean age was 72.9±1.65 years. Among...
Objective. To analyze the surgical treatment results in patients, suffering carotid arteries stenosis, using endarterectomy combination with conservative therapy.
 Materials and methods. Results of were analyzed 58 hemodynamically significant stenosis and/or presence embologenic pluck, whom from 2017 to 2019 yrs V. T. Zaytsev Institute General Urgent Surgery NAMS Ukraine, Kharkov intraoperative supportive therapy, taking into account risk for development cerebral ischemia reperfusion...
Summary. Goal. To analyze the results of surgical treatment carotid stenosis in patients with coronary heart disease order to prevent ischemic stroke.
 Materials and methods. The analysis included 18 treated SI «V. T. Zaitseva IGUS NAMNU» from 2017 2019 combined atherosclerotic lesions arteries which evaluated reserve brain.
 Results discussion. All two-stage first second groups were discharged a stable state, one had clinic transient attack postoperative period.
 Conclusions....
Вивчено особливості нейропротективної тактики хірургічного лікування атеросклеротичного стенозу внутрішньої сонної артерії. В аналіз включено 108 пацієнтів з поєднаним атеросклеротичним ураженням церебральних і каротидних артерій, яким була зроблена оцінка резервних можливостей головного мозку. На підставі результатів, які були отримані під час проведення ішемічних проб, розподілили на дві групи. До 1-ї групи увійшло 68 осіб, виконана каротидна ендартеректомія без використання тимчасового...
Transplantation of mesenchymal cells is a perspective paradigm for treatment stroke. However, after intravenous injection most infusion get in filter organs, such as lungs. Experimental model cerebral ischemia with transplantation carotid was developed. Experiments on 15 animals conducted by the females crawls age 12-36 weeks weighing 4-6 kg. The general and internal arteries were projected under local anesthesia. General artery ligated stem injected. population cages abstracted from brain...