A5090532482- Pancreatitis Pathology and Treatment
- Pancreatic and Hepatic Oncology Research
- Abdominal Surgery and Complications
- Cardiac, Anesthesia and Surgical Outcomes
- Appendicitis Diagnosis and Management
- Anorectal Disease Treatments and Outcomes
- Wound Healing and Treatments
- Medical and Biological Ozone Research
- Intestinal and Peritoneal Adhesions
- Diverticular Disease and Complications
- Hernia repair and management
- Neurological Disorders and Treatments
- Pelvic floor disorders treatments
- Laser Applications in Dentistry and Medicine
- Abdominal Trauma and Injuries
- Photodynamic Therapy Research Studies
- Sepsis Diagnosis and Treatment
- Diabetic Foot Ulcer Assessment and Management
- Liver Disease Diagnosis and Treatment
- Surgical site infection prevention
- Peripheral Artery Disease Management
- Trauma and Emergency Care Studies
- Gallbladder and Bile Duct Disorders
- Gastrointestinal disorders and treatments
- Antibiotic Use and Resistance
Kharkiv National Medical University
2015-2025
Fluor (United States)
2024
National Academy of Medical Sciences of Ukraine
2023
Lagos State Health Service Commission
2023
Ekiti State University
2023
Ospedale di Macerata
2023
University of Macerata
2023
Brunel University of London
2023
Network Group (Czechia)
2023
National University Zaporizhzhia Polytechnic
2023
Abstract Purpose There is no consensus on the standard approach for trans-sphincteric perianal fistulas (TPAF) in elderly population. The most commonly used sphincter-saving procedures are ligation of inter-sphincteric fistula tract (LIFT) and mucosal advancement flap (MAF). We aimed to evaluate incidence risk factors recurrence incontinence patients with TPAF using both approaches. Methods This retrospective study included 257 who underwent LIFT (136 patients) or MAF (121 de novo...
Abstract On January 2020, the WHO Director General declared that outbreak constitutes a Public Health Emergency of International Concern. The world has faced worldwide spread crisis and is still dealing with it. present paper represents white concerning tough lessons we have learned from COVID-19 pandemic. Thus, an international heterogenous multidisciplinary panel very differentiated people would like to share global experiences all interested especially those responsible for future...
Abstract Background Assessment of ‘physiological stress levels’ and ‘nutritional status’ before surgery is important for predicting complications indirect interventions on the pancreas. The aim this study was to determine neutrophil–lymphocyte ratio (NLR) nutritional risk index (NRI) indicators predict 90-day mortality in a cohort patients with complicated chronic pancreatitis cancer head Methods We evaluated preoperative levels NLR NRI among 225 subjects treated at different centres located...
Several recommendations and data on the treatment of acute necrotizing pancreatitis (ANP) are conflicting different surgical approaches continue to exist. We conducted a study 148 patients with ANP, who were divided into two groups: main group (n = 95) when tactics step-up approach applied principles concept Enhanced Recovery After Surgery (ERAS) in order determine this effectiveness reducing complications 30-day mortality (2017–2022); comparison 53) same tactic was used without ERAS...
This study aimed to compare the differentiation and survival of human neural stem/progenitor cells various origins in vitro after transplantation into injured spinal cord laboratory animals. Rats with simulated injury were transplanted neurosphere obtained by directed HUES6 cell lines. Fluorescence microscopy was used visualize results. HUES6#1 iPSC#1 neurospheres showed a wide range markers associated glial differentiation. The expression proliferation marker Ki67 did not exceed 25%, both...
Laparoscopic Nissen fundoplication (LNF) is the gold standard surgical intervention for gastroesophageal reflux disease (GERD). LNF can be followed by recurrent symptoms or complications affecting patient satisfaction. The aim of this study to assess value intraoperative endomanometric evaluation esophagogastric competence and pressure combined with in patients large sliding hiatus hernia (>5 cm) severe GERD (DeMeester score >100).This a retrospective, multicenter cohort study. Baseline...
This study aimed to investigate the effectiveness of combined negative pressure wound therapy (NPWT) and human amniotic membrane in patients with chronic wounds associated diabetes. A total five type 2 diabetes, including ischemic mixed forms diabetic foot syndrome, presenting lower extremities were included this study. Patients uncorrected limb ischemia excluded. The treatment protocol diabetes compensation (treatment fractional insulin therapy), anticoagulant, metabolic angiotropic...
Background and Aim of Study:Rectal fistulae make 20% all proctologic pathology.Despite numerous methods surgical treatment rectal fistulae, percentage recurrence does not tend to decrease.Complicacy correction consists in balance between radical surgery with total resection minimal damage anal sphincter.Development implementation novel mini-invasive remains actual surgery.The aim the study: compare analyze results transsphincter using standard biowelding.Materials Methods: We carried out...
Aim. To experimentally study the effect of light different ranges on proliferation and migration mesenchymal stem cells human MSCs to select its optimal parameters for treatment. Materials methods. The experiment was conducted in vitro 260 cultures isolated from peripheral blood by magnetic separation. Cells were treated with pulsed LED light: 475 nm, 516 635 nm or left unstimulated. All devices had a peak radiation intensity 80 mW/cm2. average reached 40 Irradiation carried out at room...
Background. The article is relevant to the subject matter. Benign and malignant neoplasms of pancreas represent a significant challenge in clinical practice, largely due lack early diagnostic tools aggressive nature disease. Pancreatic cancer represents 12th most commonly diagnosed 3rd leading cause mortality, accounting for approximately 3% all new cases 6% deaths worldwide. prognosis poor, difficulty detecting disease early. Consequently, developing management strategies that align with...
<title>Abstract</title> This experimental study aimed to investigate the therapeutic potential of cellular cardiomyoplasty in context refractory angina using a rodent model. The comprised five groups animals subjected different interventions, including "empty" injections, autologous mesenchymal stem cell (MSC) injections via various routes, and untreated controls. Stress load modeling was employed assess hemodynamic response, mainly focusing on heart rate changes during isopropyl...
Ten golden rules for optimal antibiotic use in hospitals: based on the publication statement of International Network Group World Antimicrobial Resistance
Summary. The use of a tourniquet to control bleeding is often necessary in the treatment patients with vascular injuries extremities. Properly performed, application can save lives, particularly extreme conditions such as battlefield. However, incorrect or prolonged result most common type peripheral nerve damage, known neuropraxia. In this article, we present and review six cases on battlefield that resulted damage. Our findings confirm need improve training medical personnel tourniquets....
Background. According to the Third International Consensus (Sepsis-3), sepsis is defined as a life-threatening organ dysfunction caused by an uncontrolled response of affected organism new infection, and septic shock sepsis-related condition characterized development circulatory failure accompanied arterial hypotension, with lactatemia requiring maintenance blood pressure vasopressors. Despite progress in diagnosing treating patients intra-abdominal infections, it continues be leading cause...
Objective. To study the effectiveness of technology combined use negative pressure wound therapy and tissue in different phases process patients with diabetes mellitus. Materials methods. We analysed results treatment 18 type II mellitus grade IV Fontaine limb ischemia at Department Acute Vascular Diseases Zaitsev Institute General Emergency Surgery National Academy Medical Sciences Ukraine 2022–2024. Diagnostic angiography by Seldinger endovascular or hybrid revascularisation were...
Sepsis-3: renewed determinations, potential problems and further practical foot steps