A5101616547- Vestibular and auditory disorders
- Ophthalmology and Eye Disorders
- Visual perception and processing mechanisms
- Glaucoma and retinal disorders
- Ophthalmology and Visual Impairment Studies
- Genetic Neurodegenerative Diseases
- Neural dynamics and brain function
- Cerebral Venous Sinus Thrombosis
- Ocular Surface and Contact Lens
- Retinal Development and Disorders
- Hearing, Cochlea, Tinnitus, Genetics
- Neuroscience and Neuropharmacology Research
- Poverty, Education, and Child Welfare
- EEG and Brain-Computer Interfaces
- Intraocular Surgery and Lenses
- Adolescent Sexual and Reproductive Health
- Neuroscience and Neural Engineering
- HIV/AIDS Research and Interventions
- Lung Cancer Diagnosis and Treatment
- Spaceflight effects on biology
- Cardiovascular and Diving-Related Complications
- Infrared Thermography in Medicine
- Family and Disability Support Research
- Cardiac Ischemia and Reperfusion
- AI in cancer detection
George Washington University
2024
Shandong Eye Hospital
2024
Dongguan People’s Hospital
2021
Shenzhen University
2019-2020
Shenzhen University Health Science Center
2019
University of California, Los Angeles
2002-2014
Tan Tock Seng Hospital
2014
University of Santa Monica
2007
Ophthalmology Associates (United States)
2005-2007
Doheny Eye Institute
2001-2005
1. The locations and connections of the smooth saccadic eye movement subregions frontal field (FEFsem FEFsac, respectively) were investigated in seven hemispheres five Cebus monkeys. supplementary was also mapped hand/arm regions dorsal ventral premotor areas localized hemispheres. Monkeys immobilized during experiments with Telazol, a dissociative anesthetic agent that has no significant effect on microstimulation-induced parameters (threshold, velocity, duration). functional defined use...
1. Intracortical microstimulation was used to localize and define the smooth saccadic eye movement subregions of frontal field (FEF) supplementary (SEF) in nine hemispheres six Cebus apella monkeys map hand/arm areas dorsal premotor area other adjacent five three C. monkeys. Monkeys were anesthetized during experiments with Telazol, a dissociative agent that has no significant effect on microstimulation-induced parameters (current threshold, velocity, duration). The functional defined use...
We compared saccadic eye movements in 21 patients with Huntington9s disease (HD) and normal subjects. In a predictive tracking task, HD were unable to anticipate normally the timing location of visual target that alternated its position predictably (± 10°, 0.5 Hz; mean latency + 170 msec -78 subjects). subjects, however, showed comparable decreases saccade (110 HD, 124 subjects) when fixation was turned off 200 before (gap task) versus after (overlap appearance an unexpected peripheral...
Recently, an emerging trend in medical image classification is to combine radiomics framework with deep learning network integrated system. Although this combination efficient some tasks, the learning-based often difficult capture effective representation of lesion regions, and prone face challenge overfitting, leading unreliable features inaccurate results, especially when sizes lesions are small or training dataset small. In addition, these combinations mostly lack feature selection...
We characterized postural stability in patients with Huntington's disease (HD) by examining their ability to use different sensory cues maintain balance and recording automatic responses externally applied perturbations. Our HD patients, like normal subjects, depended more on proprioceptive than visual balance. however, developed sway subjects when cues, or vision, were altered. Thus, showed a defect using vestibular information alone stability. The onset of compensatory motor the lower...
We have recently identified two functional subregions in the frontal eye field (FEF) of Cebus monkey, a smooth movement subregion (FEFsem) and saccadic (FEFsac). The thalamic input to these was studied quantified gain more information about influence cerebellum basal ganglia on oculomotor control mechanisms cerebral cortex. A recent study using transneuronal transport virus demonstrated that there are neurons project FEFsac with only single intervening synapse (Lunch et al., 1994). In...
Exposure to prolonged hypoxia can result in pulmonary vascular remodeling and hypertension. Hypoxia induces smooth muscle cell (PVSMC) proliferation by affecting adhesion migration secretion of extracellular matrix proteins. We previously showed that acute decreases cGMP-dependent protein kinase (PKG) activity PVSMC PKG plays a role maintaining the differentiated contractile phenotype normoxia. In this study, we investigated effect on these functions. Ovine fetal artery SMC were incubated...
Background and purpose Cerebral vasospasm following aneurysmal subarachnoid hemorrhage (aSAH) results in significant morbidity due to ischemia. Subarachnoid hematoma evacuation during aneurysm clipping reduces the incidence of vasospasm. However, studies comparing endovascular coiling with open have reported similar rates spasm. We addressed question how produces (if not less) without benefit clot by evaluating patterns among patients aSAH. hypothesize that cerebrospinal fluid (CSF)...
Deep vein thrombosis (DVT) is a disease caused by abnormal blood clots in deep veins. Accurate segmentation of DVT important to facilitate the diagnosis and treatment. In current study, we proposed fully automatic method delineation based on learning (DL) contrast enhanced magnetic resonance imaging (CE-MRI) images.
1. Intracortical microstimulation was used to map the supplementary eye field (SEF) in eight hemispheres of five Cebus apella monkeys. Monkeys were immobilized during experiments with Telazol (tiletamine HCl and zolazepam HCl), a dissociative anesthetic agent that demonstrated have no significant effect on microstimulation-induced movement parameters compared similar alert, behaviorally trained The functional subregions defined use low-threshold current (< or = 50 microA). Electrically...
To evaluate the efficacy of repeated low-level red-light (RLRL) therapy combined with optical lenses in children and adolescents myopia.
Listing's law (LL) constrains the rotational axes of saccades and pursuit eye movements to plane (LP). In velocity domain, LL is ordinarily equivalent a tilt in ocular axis equal half change position, giving angle ratio (TAR) 0.5. This study was undertaken investigate vertical saccade behavior after yaw vestibulo-ocular reflex (VOR) had driven torsion out LP, an initial condition causing position domain formulations differ.Binocular head motions were recorded with magnetic search coils eight...
Abstract To determine the level of antiretroviral treatment adherence and explore correlated factors perceived burden taking medications among people living with HIV (PLH) in a rural area China. Data were collected from 66 PLH who currently receiving treatment. Face-to-face interviews conducted during August to October, 2009. Approximately 18.2% participants failed adhere previous 30 days. A majority reported that posed them. Those higher more likely be women, have lower annual income,...
Machine learning has brought significant advancements to the field of structural health monitoring, providing flexible and efficient solutions for detecting both local global damage in various infrastructures. Local detection focuses on identifying issues such as cracks spalling specific areas concrete structures, including bridges, highways, tunnels. Techniques like artificial neural networks (ANNs) deep (DNNs) have proven effective surface defect recognition, demonstrating their...
Automated Machine Learning (AutoML) has revolutionized the field of machine learning by automating complex and time-intensive tasks such as data preprocessing, model selection, hyperparameter tuning. This study explores capabilities, limitations, practical applications six widely used AutoML tools: Auto-sklearn, TPOT, H2O.ai, Google Cloud AutoML, Microsoft Azure Amazon SageMaker Autopilot. By evaluating these tools across diverse datasets—spanning tabular data, time series, image...