A5090484692- Cardiac Imaging and Diagnostics
- Advanced MRI Techniques and Applications
- Atomic and Subatomic Physics Research
- Aortic Disease and Treatment Approaches
- Cardiovascular Function and Risk Factors
- Photoacoustic and Ultrasonic Imaging
- Coronary Artery Anomalies
- Cardiac Valve Diseases and Treatments
- Radiation Dose and Imaging
- Muscle and Compartmental Disorders
- Muscle Physiology and Disorders
- Inflammatory Myopathies and Dermatomyositis
- Advanced X-ray and CT Imaging
- Aortic aneurysm repair treatments
University of Lausanne
2019-2022
Siemens (Switzerland)
2019-2021
Coronary cardiovascular magnetic resonance angiography (CCMRA) of congenital heart disease (CHD) in pediatric patients requires accurate planning, adequate sequence parameter adjustments, lengthy scanning sessions, and significant involvement from highly trained personnel. Anesthesia intubation are commonplace to minimize movements control respiration younger subjects. To address the above concerns provide a single-click imaging solution, we applied our free-running framework for fully...
Purpose: To implement, optimize and test fast interrupted steady-state (FISS) for natively fat-suppressed free-running 5D whole-heart MRI at 1.5T 3T. Methods: FISS was implemented fully self-gated cardiac- respiratory-motion-resolved radial imaging of the heart Numerical simulations phantom scans were performed to compare fat suppression characteristics determine parameter ranges (readouts per module (NR) repetition time (TR)) effective suppression. Subsequently, data collected in ten...
To develop and characterize an algorithm that mimics human expert visual assessment to quantitatively determine the quality of three-dimensional (3D) whole-heart MR images.In this study, 3D cardiac MRI scans from 424 participants (average age, 57 years ± 18 [standard deviation]; 66.5% men) were used generate image algorithm. A deep convolutional neural network for (IQ-DCNN) was designed, trained, optimized, cross-validated on a clinical database 324 (training set) scans. On separate test set...
Radial self-navigated (RSN) whole-heart coronary cardiovascular magnetic resonance angiography (CCMRA) is a free-breathing technique that estimates and corrects for respiratory motion. However, RSN has been limited to 1D rigid correction which often insufficient patients with complex patterns. The goal of this work therefore improve the robustness quality 3D radial CCMRA by incorporating both motion information nonrigid intra-acquisition data into framework called focused navigation (fNAV).
Purpose Whole‐heart MRA techniques typically target predetermined motion states, address cardiac and respiratory dynamics independently, require either complex planning or computationally demanding reconstructions. In contrast, we developed a fast data‐driven reconstruction algorithm with minimal physiological assumptions compatibility ungated free‐running sequences. Theory Methods We propose similarity‐driven multi‐dimensional binning (SIMBA) that clusters continuously acquired k‐space data...
Purpose Navigator‐gated 3D bSSFP whole‐heart coronary MRA has been evaluated in several large studies including a multi‐center trial. Patient have also performed with more recent self‐navigated techniques. In this study, these two approaches are compared side‐by‐side using Cartesian navigator‐gated and corrected (CNG) radial (RSN) protocol from published patient studies. Methods Sixteen healthy subjects were examined both sequences on 1.5T scanner. Assessment of the visibility ostia...
Whole-heart magnetic resonance angiography (MRA) requires sophisticated methods accounting for respiratory motion. Our purpose was to evaluate the image quality of compressed sensing-based motion-resolved three-dimensional (3D) whole-heart MRA compared with self-navigated motion-corrected in patients known thoracic aorta dilation. Twenty-five were prospectively enrolled this ethically approved study. 1.5-T acquired using a prototype 3D radial steady-state free-precession free-breathing...
Patients with thoracic aortic dilatation who undergo annual computed tomography angiography (CTA) are subject to repeated radiation and contrast exposure. The purpose of this study was evaluate the feasibility a non-contrast, respiratory motion-resolved whole-heart cardiovascular magnetic resonance (CMRA) technique against reference standard CTA, for quantitative assessment anatomy monitoring disease progression in patients dilatation. Twenty-four (68.6 ± 9.8 years) prospectively underwent...
Abstract Introduction/Aims Fat‐referenced magnetic resonance imaging (MRI) has emerged as a promising volumetric technique for measuring muscular volume and fat in neuromuscular disorders, but the experience inflammatory myopathies remains limited. Therefore, this work aimed at describing how sporadic inclusion body myositis (sIBM) manifests on standardized fat‐referenced MRI muscle measurements, including within‐scanner repeatability, natural progression rate, relationship to clinical...
Background: RSN whole-heart CMRA is a technique that estimates and corrects for respiratory motion. However, has been limited to 1D rigid correction which often insufficient patients with complex patterns. The goal of this work therefore improve the robustness quality 3D radial by incorporating both motion information nonrigid intra-acquisition data into framework called focused navigation (fNAV). Methods: We applied fNAV 500 sets from numerical simulation, 22 healthy volunteers, 549 cardiac...