We performed technical optimization followed by a pilot clinical study of quiescent-interval single-shot MR angiography for peripheral vascular disease. Quiescent-interval acquires data using modified electrocardiographic (ECG)-triggered, fat suppressed, two-dimensional, balanced steady-state, free precession pulse sequence incorporating slice-selective saturation and quiescent interval maximal enhancement inflowing blood. Following at 1.5 T, was in patients with disease, contrast-enhanced...

Purpose To assess the diagnostic performance of quiescent-interval single-shot (QISS) magnetic resonance (MR) angiography, a nonenhanced two-dimensional electrocardiographically gated balanced steady-state free precession examination for evaluation symptomatic chronic lower limb ischemia. Materials and Methods For this prospective institutional review board–approved, HIPAA-compliant study, board waived requirement informed patient consent. The QISS MR angiography technique was evaluated in...

Background Luminal and hemodynamic evaluations of the cervical arteries inform diagnosis management patients with arterial disease. Purpose To demonstrate a 3D nonenhanced quantitative quiescent interval slice‐selective (qQISS) magnetic resonance angiographic (MRA) strategy that provides simultaneous luminal evaluation arteries. Study Type Prospective. Subjects Six healthy volunteers (3 female, 3 male, age = 35.7 ± 10.3 years) 14 cerebrovascular disease (12 2 56.6 14.0 years). Field...

OBJECTIVE. The joint guidelines of the American College Cardiology and Heart Association support use contrast-enhanced MR angiography (CEMRA) to diagnose location degree stenosis in patients with known or suspected peripheral arterial disease (PAD). high prevalence chronic renal impairment diabetic PAD need for doses gadolinium-based contrast agents place them at risk nephrogenic systemic fibrosis. purpose our study was evaluate accuracy rapid technique quiescent-interval single-shot (QISS)...

For evaluation of the pulmonary arteries in patients suspected embolism, CT angiography (CTA) is first-line imaging test with contrast-enhanced MR (CEMRA) a potential alternative. Disadvantages CTA include exposure to ionizing radiation and an iodinated contrast agent, while CEMRA sensitive respiratory motion requires gadolinium-based agent. The primary goal our technical feasibility study was evaluate arterial conspicuity using breath-hold free-breathing implementations recently-developed...

Purpose To probe the feasibility of deep learning‐based super‐resolution (SR) reconstruction applied to nonenhanced MR angiography (MRA) head and neck. Methods High‐resolution 3D thin‐slab stack‐of‐stars quiescent interval slice‐selective (QISS) MRA neck was obtained in eight subjects (seven healthy volunteers, one patient) at 3T. The spatial resolution high‐resolution ground‐truth data slice‐encoding direction reduced by factors 2 6. Four neural network (DNN) SR reconstructions were...

Standard Cartesian time-of-flight (TOF) head magnetic resonance angiography (MRA) is routinely used to evaluate the intracranial arteries, but does not provide quantitative hemodynamic information that useful for patient risk stratification as well monitoring treatment and tracking changes in blood flow over time. Quantitative TOF (qTOF) MRA represents a new efficient method simultaneous evaluating arteries quantifying velocity, it has yet been evaluated patients with cerebrovascular disease.

Purpose To develop a navigator technique enabling free‐breathing acquisition to afford sufficient signal averaging for quantitative renal perfusion measurement using arterial spin labeling MRI. Methods A novel two‐dimensional (2D) was implemented in concert with flow‐sensitive alternating inversion recovery (FAIR) preparation and true fast imaging steady precession (True‐FISP) readout. The images were obtained low‐resolution low angle shot readout at end of each acquisition. retrospective...

The objective of our study was to assess the diagnostic performance quiescent-interval single-shot (QISS) MR angiography (MRA) at 3 T for evaluation chronic lower limb ischemia.For this prospective study, 25 patients referred extremity suspected or known peripheral arterial disease were imaged on a 3-T system using QISS MRA. Contrast-enhanced MRA extremities acquired each patient time initial visit and served as noninvasive reference standard. Two blinded reviewers separately graded degree...

Purpose: To implement, optimize and test fast interrupted steady-state (FISS) for natively fat-suppressed free-running 5D whole-heart MRI at 1.5T 3T. Methods: FISS was implemented fully self-gated cardiac- respiratory-motion-resolved radial imaging of the heart Numerical simulations phantom scans were performed to compare fat suppression characteristics determine parameter ranges (readouts per module (NR) repetition time (TR)) effective suppression. Subsequently, data collected in ten...

It is well known that magnetic susceptibility variations lead to signal voids in MRI. However, recent work has shown positive-contrast imaging of susceptibility-induced field can provide enhancements rather than losses. In this paper, we propose a new method for generating positive contrast from off-resonant spins with steady-state free precession (SSFP) resonance imaging. Based on theory and experiments, demonstrate images be acquired the presence susceptibility-shift media low flip angle...

This HIPAA-compliant study had institutional review board approval. Informed consent was obtained. The purpose to prospectively evaluate a segmented three-dimensional (3D) double inversion recovery (DIR)–prepared steady-state free precession (SSFP) magnetic resonance (MR) imaging sequence for fast high-spatial-resolution black-blood carotid arterial wall imaging. Carotid wall–lumen contrast-to-noise ratio (CNR) obtained with this compared those two-dimensional (2D) single- and multisection...

Coronary magnetic resonance angiography (MRA) is usually obtained with a free-breathing navigator-gated 3D acquisition. Our aim was to develop an alternative breath-hold approach that would allow the coronary arteries be evaluated in much shorter time and without risk of degradation by respiratory motion artifacts. For this purpose, we implemented breath-hold, non-contrast-enhanced, quiescent-interval slice-selective (QISS) 2D technique. Sequence performance compared at 1.5 3 Tesla using...

Abstract Purpose To compare two multislice turbo spin‐echo (TSE) carotid artery wall imaging techniques at 1.5 T and 3.0 T, to investigate the feasibility of higher spatial resolution T. Materials Methods Multislice proton density‐weighted (PDW), T2‐weighted (T2W), T1‐weighted (T1W) inflow/outflow saturation band (IOSB) rapid extended coverage double inversion‐recovery (REX‐DIR) TSE was performed on six healthy volunteers using time‐, coverage‐, resolution–matched (0.47 × 0.47 3 mm )...

Abstract Purpose To assess the feasibility of black‐blood turbo spin‐echo imaging left anterior descending coronary artery wall at 3 Tesla under free‐breathing and breath‐hold conditions. Materials Methods Proton density‐weighted was performed on 15 volunteers a T whole body scanner with an eight channel phased array coil. Volunteers were imaged during (with navigators, N = 5), or ( both 2). Imaging not possible in three due to either gradient radiofrequency (RF) coupling electrocardiogram...

Dark-Blood MRI of the Thoracic Aorta with 3D Diffusion-Prepared Steady-State Free Precession: Initial Clinical EvaluationIoannis Koktzoglou1 2 3, Anish Kirpalani1 4, Timothy J. Carroll1 2, Debiao Li1 and James C. Carr1Audio Available | Share

To compare pulsed arterial spin labeling (PASL) and pseudocontinuous (PCASL) for nonenhanced extracranial carotid MR angiography (MRA).Parametric signal equations PASL PCASL MRA were formulated compared. Volunteer imaging (n=7) at 1.5 Tesla was performed to the methods over a broad range of repetition times. Empirical results compared with theoretical predictions. The feasibility optimal method investigated in patients (n=2) sonographically documented artery disease.In volunteers, provided...

Purpose To test the feasibility of a quiescent interval low-angle shot (QLASH) sequence for nonenhanced MR angiography (MRA) extracranial carotid arteries at 3 T. Methods The were imaged using QLASH MRA in healthy volunteers and patients with arterial disease. impact three gating strategies (electrocardiographic-gated, pulse-gated, ungated) was evaluated. Image quality comparisons made respect to two-dimensional (2D) time flight (TOF) contrast-enhanced (CEMRA) patients. Stenoses graded....

To optimize and preliminarily evaluate a three-dimensional (3D) radial balanced steady-state free precession (bSSFP) arterial spin labeled (ASL) sequence for nonenhanced MR angiography (MRA) of the extracranial carotid arteries.The arteries 13 healthy subjects 2 patients were imaged on 1.5 Tesla MRI system using an undersampled 3D bSSFP providing scan time ∼4 min 1 mm(3) isotropic resolution. A hybridized scheme that combined pseudocontinuous pulsed ASL was used to maximize coverage. The...