Chiara Costa

ORCID: 0000-0002-6839-0725
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About
Contact & Profiles
Research Areas
  • Carcinogens and Genotoxicity Assessment
  • Pesticide Exposure and Toxicity
  • Occupational and environmental lung diseases
  • Genomics, phytochemicals, and oxidative stress
  • Phytochemicals and Antioxidant Activities
  • Paraoxonase enzyme and polymorphisms
  • Sleep and Work-Related Fatigue
  • Immunotoxicology and immune responses
  • Pleural and Pulmonary Diseases
  • COVID-19 and Mental Health
  • Air Quality and Health Impacts
  • Healthcare professionals’ stress and burnout
  • Occupational exposure and asthma
  • Natural Antidiabetic Agents Studies
  • Circadian rhythm and melatonin
  • Long-Term Effects of COVID-19
  • Sleep and related disorders
  • Gut microbiota and health
  • Heavy Metal Exposure and Toxicity
  • Health, Environment, Cognitive Aging
  • Workplace Health and Well-being
  • Vector-borne infectious diseases
  • Viral Infections and Vectors
  • Toxic Organic Pollutants Impact
  • Animal testing and alternatives

University of Messina
2015-2024

Magna Graecia University
2015-2024

Azienda Sanitaria Unità Locale di Reggio Emilia
2020-2021

Istituti di Ricovero e Cura a Carattere Scientifico
2020-2021

GTx (United States)
2019

University of Turin
2017

Azienda Ospedaliero Universitario Mater Domini
2015

Massachusetts General Hospital
2013

University of Catania
2012

Azienda Ospedaliera Universitaria Policlinico "G. Martino"
2003-2009

A huge volume of literature data suggests that a diet rich in fruits and vegetables, mostly due to the contribution natural polyphenols, could reduce incidence specific cancers. Resveratrol, epigallocatechin gallate curcumin are among most extensively studied polyphenols: The majority effects attributed these compounds linked their antioxidant anti‑inflammatory properties. multiple mechanisms involved include modulation molecular events signaling pathways associated with cell survival,...

10.3892/ijfn.2020.9 article EN International Journal of Functional Nutrition 2020-10-05

Stressful life events, are differently handled by women and men. This study evaluates gender differences in perceived stress health status among a sample of subjects going through transition period from unemployment to work. cross-sectional enrolled 395 participants, 245 men (62%) 150 (38%) women, between 19 67 years, that were be hired for 6-month contract. Before being employed, all participants underwent mandatory protocol consisting general medical check. Stress assessment was performed...

10.3389/fpubh.2021.640454 article EN cc-by Frontiers in Public Health 2021-04-01

The antioxidant activity of extracts from Capparis spinosa L. buds was evaluated using different in vitro tests: ascorbate/Fe(2+)-mediated lipid peroxidation microsomes rat liver; bleaching 1,1-diphenyl-2-picryl-hydrazyl radical; and autoxidation Fe(2+) ion the presence bathophenanthroline disulfonate. methanolic extract showed strong activities all these tests. amount total phenols determined extract. In addition, level rutin calculated as 0.39% (w/w) by HPLC analysis. Our findings indicate...

10.1021/jf010678d article EN Journal of Agricultural and Food Chemistry 2002-02-01

• Gasoline station attendants have higher urinary t,t,-MA and 8-OHdG levels. There is strong correlation between benzene exposure level. levels are significantly correlated also with job seniority. Low-level chronic to can determine oxidative damage on DNA. The present study aims investigate the relation low-dose occurrence of DNA in gasoline workers, as well possible role interfering or confounding factors. Urine were evaluated by a competitive immunoassay group 80 men, employed stations...

10.1016/j.toxrep.2017.05.008 article EN cc-by-nc-nd Toxicology Reports 2017-01-01

Environmental or occupational exposure to pesticides is considered one of the main risk factors for development various diseases. Behind pesticide-associated pathologies, there are both genetic and epigenetic alterations, where these latter mainly represented by alteration in expression levels microRNAs change methylation status DNA. At present, no studies have comprehensively evaluated alterations induced pesticides; therefore, aim present study was identify modifications gene miRNA DNA...

10.3390/ijerph18168697 article EN International Journal of Environmental Research and Public Health 2021-08-17

The sudden burst of the COVID-19 pandemic has changed work environment in favor remote working, affecting perception quality, satisfaction and performance. This crisis also influenced workers' mood, sleep quality general everyday life. Our main purpose this study was to give empirical contributions about home office workers experiencing working during by assessing mood spectrum variations, disturbances impact cross-sectional performed between November December 2020 through an online...

10.3390/ijerph19041990 article EN International Journal of Environmental Research and Public Health 2022-02-10

This review summarizes the current knowledge linking cancer and neuro-degenerative diseases to dysregulation of microRNA network following pesticide exposure. Most findings revealed differential miRNA expression targeting biomolecules pathways involved in various neoplastic localizations neurodegenerative diseases. A growing body evidence recent literature indicates that alteration specific miRNAs can represent an early biomarker disease exposure chemical agents, including pesticides....

10.1016/j.toxrep.2020.05.003 article EN cc-by-nc-nd Toxicology Reports 2020-01-01
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