A5030783225- Neuroinflammation and Neurodegeneration Mechanisms
- Tryptophan and brain disorders
- Biosensors and Analytical Detection
- Adenosine and Purinergic Signaling
- Advanced biosensing and bioanalysis techniques
- Hemoglobin structure and function
- Meningioma and schwannoma management
- Vascular Malformations Diagnosis and Treatment
- Cancer-related gene regulation
- Electrocatalysts for Energy Conversion
- Neurosurgical Procedures and Complications
- Asymmetric Hydrogenation and Catalysis
- Angiogenesis and VEGF in Cancer
- Phytochemical compounds biological activities
- Acupuncture Treatment Research Studies
- Photoacoustic and Ultrasonic Imaging
- Advanced Breast Cancer Therapies
- Traumatic Brain Injury and Neurovascular Disturbances
- Epigenetics and DNA Methylation
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Pain Mechanisms and Treatments
- Long-Term Effects of COVID-19
- Endoplasmic Reticulum Stress and Disease
- Cancer Mechanisms and Therapy
- Effects of Radiation Exposure
Liaoning University of Traditional Chinese Medicine
2022-2024
Soochow University
2016-2023
Huazhong University of Science and Technology
2023
First Affiliated Hospital of Soochow University
2022
Army Medical University
2022
Southern University of Science and Technology
2020
Shandong University
2011-2012
Novel electrochemiluminescence resonance energy transfer (ECRET) between an emitter electrochemically generated by luminol as the donor and luminescent quantum dots acceptor is investigated. The ECRET technique can be used to study interactions conformational changes of proteins.
Radiation-induced skin injury, which remains a serious concern in radiation therapy, is currently believed to be the result of vascular endothelial cell injury and apoptosis. Here, we established model acute radiation-induced compared effect different growth factors on healing by observing changes microcirculation Vascular factor (VEGF) was more effective at inhibiting apoptosis preventing progression than other factors. A new strategy for improving bioavailability developed loading VEGF...
A facile route for on-demand hydrogen production <italic>via</italic> simply controlling the mixing process of a KBH<sub>4</sub> solution and an aqueous ISOBAM-104 stabilized Co<sup>2+</sup> ions.
Histone H3 lysine 4 (H3K4) methylation is generally recognized as a prominent marker of gene activation. While Set1/Mll complexes are major methyltransferases that responsible for H3K4 methylation, the mechanism how these recruited into target promotor still unclear. Here, starting with an affinity purification-mass spectrometry approach, we have found Isl1, highly tissue-specific expressed LIM/homeodomain transcription factor, physically associated complexes. We then show Wdr5 directly...
Electroacupuncture (EA) is a widely used traditional Chinese medicine method to manage various diseases, including cerebral ischemia-reperfusion injury (CIRI).We assessed the neuroprotective effects of EA and examined its mechanism in rat model middle artery occlusion-reperfusion (MCAO/R). The gait analysis was performed evaluate effects. Western blot immunohistochemistry assays were carried out determine molecular mechanisms EA.Male SD rats randomly divided into sham operation group, right...
Bruceantinol (BOL), isolated from the dried fruit of Brucea javanica (L.) Merr., exhibits cytotoxic effects on breast cancer cells. However, underlying mechanism remains to be fully addressed. In this paper, MCF-7 and MDA-MB-231 human cell lines were used as experimental models uncover how BOL inhibits growth. The growth, proliferation, cycle, apoptosis investigated using MTT assays, EdU incorporation flow cytometry, respectively. Bioinformatics techniques applied predict key targets in...
To retrospectively analyze the clinical data of patients with pineal region meningioma. All underwent combined endoscopic and microsurgical procedure by modified Poppen approach (double-scopic technique) between January 2018 March 2021 in Department Neurosurgery First Affiliated Hospital Soochow University. A total tumor resection was achieved all without deaths. meningiomas were pathologically confirmed. During follow-up period, none 10 experienced progression, 4 treated radiotherapy after...
Abstract Background Previous studies have mainly focused on the immediate effect of drugs autism spectrum disorders (ASDs) and complex heterogeneous neurodevelopmental that been proven to be involved with chronic inflammation central nervous system. Our prior work has explored positive role activation adenosine 2A receptors (A2ARs) in protecting adult BTBR T + Itpr3 tf /J mice against autism-related behaviour from early postnatal period. However, exact mechanism underlying protection A2ARs...
Abstract Background: Studies mainly focused on the immediate effect of drugs Autism spectrum disorders (ASD), complex heterogeneous neurodevelopmental disorders, which been proved involved with chronic inflammation central nervous system. Our studies have explored positive role activation adenosine 2A receptors (A2ARs) in protect adult BTBR mice against autism related behavior from early postnatal period. However, exact mechanism underlying protection A2ARs has not comprehensively...