William R. Lewis

ORCID: 0000-0002-6844-2505
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About
Contact & Profiles
Research Areas
  • Atrial Fibrillation Management and Outcomes
  • Cardiac Arrhythmias and Treatments
  • Cardiac electrophysiology and arrhythmias
  • Cardiac Imaging and Diagnostics
  • Cardiac pacing and defibrillation studies
  • Acute Myocardial Infarction Research
  • Health Systems, Economic Evaluations, Quality of Life
  • Cardiovascular and exercise physiology
  • Cardiovascular Effects of Exercise
  • Heart Failure Treatment and Management
  • Venous Thromboembolism Diagnosis and Management
  • Heart Rate Variability and Autonomic Control
  • Cardiac, Anesthesia and Surgical Outcomes
  • Cardiac Health and Mental Health
  • Cardiac Ischemia and Reperfusion
  • Blood Pressure and Hypertension Studies
  • Water Quality and Resources Studies
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Ultrasound in Clinical Applications
  • Cardiac Arrest and Resuscitation
  • Clinical practice guidelines implementation
  • Acute Ischemic Stroke Management
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Cardiovascular Function and Risk Factors
  • Cardiovascular and Diving-Related Complications

MetroHealth
2008-2023

Case Western Reserve University
2010-2022

MetroHealth Medical Center
2010-2022

Ollscoil na Gaillimhe – University of Galway
2021

Karolinska University Hospital
2021

Karolinska Institutet
2021

Royal Brompton Hospital
2021

VA Palo Alto Health Care System
2014-2021

Stanford University
2010-2021

University of California, Davis
2000-2019

Background— Together with pulmonary veins, many extrapulmonary vein areas may be the source of initiation and maintenance atrial fibrillation. The left appendage (LAA) is an underestimated site Here, we report prevalence triggers from LAA best strategy for successful ablation. Methods Results— Nine hundred eighty-seven consecutive patients (29% paroxysmal, 71% nonparoxysmal) undergoing redo catheter ablation fibrillation were enrolled. Two sixty-six (27%) showed firing became study...

10.1161/circulationaha.109.928903 article EN Circulation 2010-07-07

Background— Catheter ablation of atrial fibrillation is associated with the potential risk periprocedural stroke, which can range between 1% and 5%. We developed a prospective database to evaluate prevalence stroke over time assess whether anticoagulation strategy use open irrigation catheter have resulted in reduction this complication. Methods Results— collected data from 9 centers performing same procedure protocol. divided patients into 3 groups: an 8-mm off warfarin (group 1), irrigated...

10.1161/circulationaha.109.921320 article EN Circulation 2010-06-02

Background— Obstructive sleep apnea (OSA) may be associated with pulmonary vein antrum isolation (PVAI) failure. The aim of the present study was to investigate if treatment continuous positive airway pressure (CPAP) improved PVAI success rates. Methods and Results— From January 2004 December 2007, 3000 consecutive patients underwent PVAI. Patients were screened for OSA CPAP use. Six hundred forty (21.3%) had OSA. more procedural failures ( P =0.024) hematomas <0.001). Eight percent...

10.1161/circep.109.858381 article EN Circulation Arrhythmia and Electrophysiology 2010-08-06

Background: Evidence-based guidelines from the American Heart Association are voluntary, and adherence is highly variable across country.Get With The Guidelines (GWTG) a national quality improvement program sponsored developed by Association.The objective of this study was to evaluate whether participation in GWTG associated with greater for coronary artery disease (CAD).Methods: Data on were obtained Hospital Compare, grouping hospitals according GWTG-CAD January 1, 2004: hospitals, n =...

10.1001/archinte.168.16.1813 article EN Archives of Internal Medicine 2008-09-08

Background: Efforts to improve prescription of oral anticoagulation (OAC) drugs in patients with atrial fibrillation have had limited success improving guideline adherence. Methods: We evaluated adherence the American College Cardiology/American Heart Association performance measures for OAC eligible a CHA 2 DS -VASc score ≥2 and trends over time Association’s Get With The Guidelines–AFIB (atrial fibrillation) registry. Adjusted associations in-hospital outcomes were also determined. cohort...

10.1161/circulationaha.118.035909 article EN Circulation 2019-01-31

Background: Catheter ablation is an increasingly used treatment for symptomatic atrial fibrillation (AF). However, there are limited prospective, nationwide data on patient selection and procedural characteristics. This study describes characteristics, techniques, patterns, safety outcomes of patients undergoing AF ablation. Methods: A total 3139 between 2016 2018 in the Get With The Guidelines-Atrial Fibrillation registry from 24 US centers were included. Patient demographics, medical...

10.1161/circep.119.007944 article EN Circulation Arrhythmia and Electrophysiology 2020-07-24

As health systems around the world increasingly look to measure and improve value of care that they provide patients, being able outcomes matter most patients is vital. To support shift towards value-based in atrial fibrillation (AF), International Consortium for Health Outcomes Measurement (ICHOM) assembled an international Working Group (WG) 30 volunteers, including professionals patient representatives develop a standardized minimum set benchmarking delivery clinical settings.

10.1093/eurheartj/ehz871 article EN cc-by-nc European Heart Journal 2019-12-02

The frequency and characterization of patients receiving cardiac resynchronization therapy (CRT) are largely unknown since the publication pivotal clinical trials subsequent incorporation CRT into American College Cardiology/American Heart Association guidelines for heart failure.We analyzed 33,898 admitted from January 2005 through September 2007 to 228 hospitals participating in Association's Get With Guidelines-Heart Failure program. There were 4201 (12.4%) discharged alive with CRT,...

10.1161/circulationaha.108.773838 article EN Circulation 2008-08-13

Significant disparities have been reported in the application of evidence-based guidelines treatment coronary artery disease (CAD) women and elderly. We hypothesized that participation a quality-improvement program could improve care for all patients thus narrow gaps over time.Treatment 237 225 hospitalized with CAD was evaluated Get With Guidelines-CAD from 2002 to 2007. Six quality measures were eligible without contraindications: aspirin on admission discharge, beta-blockers use at...

10.1161/circoutcomes.108.824763 article EN Circulation Cardiovascular Quality and Outcomes 2009-10-28
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