Michael Smith

ORCID: 0000-0003-2060-172X
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Glaucoma and retinal disorders
  • Ovarian cancer diagnosis and treatment
  • Retinal Diseases and Treatments
  • Cardiac Arrhythmias and Treatments
  • Bone health and treatments
  • Atrial Fibrillation Management and Outcomes
  • Cardiovascular Function and Risk Factors
  • Endometrial and Cervical Cancer Treatments
  • Radiopharmaceutical Chemistry and Applications
  • Gyrotron and Vacuum Electronics Research
  • Prostate Cancer Treatment and Research
  • Ocular Surface and Contact Lens
  • Corneal surgery and disorders
  • Intraperitoneal and Appendiceal Malignancies
  • Intraocular Surgery and Lenses
  • Plasma Diagnostics and Applications
  • Neural Networks and Applications
  • Pulsed Power Technology Applications
  • Prostate Cancer Diagnosis and Treatment
  • Colorectal Cancer Treatments and Studies
  • Multiple Myeloma Research and Treatments
  • Cardiac pacing and defibrillation studies
  • Radiation Detection and Scintillator Technologies
  • Cancer Treatment and Pharmacology
  • Hemodynamic Monitoring and Therapy

Boston University
2024

Sandia National Laboratories
2023

The University of Texas at El Paso
2023

Stanford University
2023

Inova Fairfax Hospital
2023

University of California, Irvine
2023

University of Alabama at Birmingham
2022

Royal Devon & Exeter NHS Foundation Trust
2018-2022

Viventia Bio (Canada)
2021

Mayo Clinic Hospital
2021

The authors explored the clinical correlates of ventricular enlargement in schizophrenia by comparing 16 patients with "large" ventricles (ventricles more than I SD above control mean) smallest from a sample 52 schizophrenic patients. Patients showed some impairment sensorium and had preponderance "negative" symptoms (e.g., alogia, affective flattening, avolition, anhedonia), while those small were characterized "positive" delusions, hallucinations, positive formal thought disorder, bizarre...

10.1176/ajp.139.3.297 article EN American Journal of Psychiatry 1982-03-01

The regional distributions of monoamine oxidase (MAO) types A and B have been identified in human brain vivo with intravenously injected 11 C-labeled suicide enzyme inactivators, clorgyline L-deprenyl, positron emission tomography. rapid uptake retention radioactivity for both C tracers indicated irreversible trapping. anatomical distribution paralleled the MAO autopsy material. corpus striatum, thalamus, brainstem contained high activity. magnitudes [ C]clorgyline L-[ C]deprenyl were...

10.1126/science.3099392 article EN Science 1987-01-23

Ventricular enlargement in schizophrenia as measured by ventricular-brain ratio (VBR) has been described three different research groups. Because of the possibility that samples might not be representative broad population schizophrenic patients, questions have raised about generalizability. The authors report on ventricular a rigorously defined but sample patients intermittently hospitalized living community. They provide additional evidence does occur although at rates high those...

10.1176/ajp.139.3.292 article EN American Journal of Psychiatry 1982-03-01

Background: A pocket mobile echocardiography (PME) device is commercially available for clinical use, but public data documenting its accuracy compared with standard transthoracic (TTE) are not available. Objective: To compare the of rapidly acquired PME images those by TTE. Design: Cross-sectional study. At time referral TTE, ultrasonographers first in 5 minutes or less. Ultrasonographers were blinded to indication imaging image results when obtaining TTE images. Two experienced...

10.7326/0003-4819-155-1-201107050-00005 article EN Annals of Internal Medicine 2011-07-05

Left ventricular outflow tract velocity time integral (LVOT VTI) is a measure of cardiac systolic function and output. Heart failure patients with low output are known to have poor cardiovascular outcomes. Thus, extremely LVOT VTI may predict heart at highest risk for mortality. Patients were identified from single-center database. Baseline characteristics related clinical outcomes (death, LVAD) obtained 12 months. Correlation between endpoints the following variables analyzed: ejection...

10.1186/s12947-017-0109-4 article EN cc-by Cardiovascular Ultrasound 2017-07-03

The aim of this study was to determine the effects initial treatment with a GnRH agonist on body composition in asymptomatic men nonmetastatic prostate cancer. Forty locally advanced, node-positive or biochemically recurrent cancer, no radiographic evidence metastases, and prior androgen deprivation therapy were treated leuprolide 3-month depot 22.5 mg im every 12 wk for 48 wk. main outcome measures percentage changes weight, fat mass, lean distribution, muscle size after Thirty-two subjects...

10.1210/jc.87.2.599 article EN The Journal of Clinical Endocrinology & Metabolism 2002-02-01

As deep neural networks (DNNs) become increasingly common, concerns about their robustness do as well. A longstanding problem for deployed DNNs is behavior in the face of unfamiliar inputs; specifically, these models tend to be overconfident and incorrect when encountering out-of-distribution (OOD) examples. In this work, we present a topological approach characterizing OOD examples using latent layer embeddings from DNNs. Our goal identify features, referred landmarks, that indicate We...

10.48550/arxiv.2501.12522 preprint EN arXiv (Cornell University) 2025-01-21

Purpose: Conjunctival complications may occur after glaucoma drainage device surgery. We analyzed the frequency, risk factors, management and outcomes of Ahmed valve (AGV)-related conjunctival complications. Methods: Retrospective review postoperative in patients undergoing AGV insertion. Only subjects with ≥1-year follow-up were included. Results: The charts 158 a median age 64±16.2 years reviewed. Median was 43.5 months (range, 12 to 103 mo). Fifty-three (33.5%) wound dehiscences 14 (8.9%)...

10.1097/ijg.0b013e31826ab693 article EN Journal of Glaucoma 2012-10-11

To review the results of phacovitrectomy for primary retinal detachment repair in presbyopes.The outcome and complications surgery were examined a retrospective case series 93 presbyopic patients who underwent phacoemulsification vitrectomy rhegmatogenous detachment.Eighty-two (88.2%) had reattachment with single procedure. The final rate further procedures was 97.8%. Two (2.2%) whom did not occur declined after repair. All redetachments due to proliferative vitreoretinopathy. median Snellen...

10.1097/01.iae.0000243066.19645.de article EN Retina 2007-03-30

Despite local therapy with curative intent, approximately 30% of men suffer from biochemical relapse. Though some these PSA relapses are not life threatening, many eventually progress to metastatic disease and die prostate cancer. Local is an option for men, but have progression following salvage attempts. One significant issue in this setting the lack reliable imaging biomarkers guide use therapy, as likely reason a low cure rate presence undetected micrometastatic outside prostate/prostate...

10.1155/2012/921674 article EN cc-by Advances in Urology 2012-01-01

Abstract BACKGROUND Bisphosphonates have been used to treat bone metastases in hormone‐refractory prostate cancer (HRPC), but certain agents associated with renal toxicity. For this observational study, the authors assessed risk of impairment patients HRPC who received zoledronic acid from December 1999 April 2005. METHODS A comprehensive medical records review was performed a major tertiary oncology center (n = 122 patients). The primary outcome defined as an increase ≥0.5 mg/dL or ≥1.0...

10.1002/cncr.22504 article EN Cancer 2007-02-20

Left atrial appendage (LAA) occlusion or ligation is a novel approach to stroke prevention in fibrillation that may obviate the need for long-term anticoagulation. The Lariat device has received Food and Drug Administration 510K clearance approximation of soft tissue been applied transcatheter LAA using combined trans-pericardial transseptal approach. occurrence late leak after its percutaneous management not previously reported. Herein, we report three cases with reconstitution initially...

10.1002/ccd.25251 article EN Catheterization and Cardiovascular Interventions 2013-10-15

Whole-abdominal irradiation was delivered to 22 patients with epithelial carcinoma of the ovary who had persistent disease after chemotherapy. Seventeen were treated an open whole-abdominal field and 5 moving-field technique. Eleven also received a pelvic boost. Two nine microscopic at second look are alive disease-free 34 52 months, respectively. There no salvages among patient macroscopic disease. Major complications included bowel obstruction in three radiation enteritis one patient. is...

10.1002/1097-0142(19860815)58:4<880::aid-cncr2820580413>3.0.co;2-z article EN Cancer 1986-08-15
Coming Soon ...