A5085679140- Glaucoma and retinal disorders
- Retinal Diseases and Treatments
- Retinal Imaging and Analysis
- Corneal surgery and disorders
- Pharmaceutical industry and healthcare
- Acute Ischemic Stroke Management
- Reproductive Health and Contraception
- Coronary Artery Anomalies
- Ophthalmology and Eye Disorders
- Cardiac Arrhythmias and Treatments
- Cerebral Venous Sinus Thrombosis
- Moyamoya disease diagnosis and treatment
- Retinal Development and Disorders
- Pharmaceutical Economics and Policy
- Botulinum Toxin and Related Neurological Disorders
- Retinal and Optic Conditions
- Ocular Surface and Contact Lens
- Traumatic Brain Injury and Neurovascular Disturbances
- Vascular Malformations Diagnosis and Treatment
- Neurological Disorders and Treatments
- Corneal Surgery and Treatments
- Protein Kinase Regulation and GTPase Signaling
- Cardiac Structural Anomalies and Repair
- Cardiovascular Syncope and Autonomic Disorders
- Congenital Heart Disease Studies
Toho University Ohashi Medical Center
2011-2021
Toho University
2011-2021
Toronto Western Hospital
2011-2012
University of Toronto
2009-2012
Kagoshima University
2005
Purpose: Conjunctival complications may occur after glaucoma drainage device surgery. We analyzed the frequency, risk factors, management and outcomes of Ahmed valve (AGV)-related conjunctival complications. Methods: Retrospective review postoperative in patients undergoing AGV insertion. Only subjects with ≥1-year follow-up were included. Results: The charts 158 a median age 64±16.2 years reviewed. Median was 43.5 months (range, 12 to 103 mo). Fifty-three (33.5%) wound dehiscences 14 (8.9%)...
To characterize laser speckle flowgraphy (LSFG) pulse waveform parameters for ocular circulation evaluation, a multicenter, prospective, cross-sectional study was conducted in 111 eyes of 86 healthy Japanese individuals. Optic nerve head (ONH) tissue-area, vessel-area mean blur rate (MT and MV, respectively), MT MV were obtained using LSFG ONH structural planimetry. Multivariate linear mixed-effects modeled regression analysis identified factors contributing to MT- or MV-waveforms age,...
Purpose . To compare optical coherence tomography angiography (OCT-A) and laser speckle flowgraphy (LSFG) for the diagnosis of normal-tension glaucoma (NTG). Methods Twenty-eight eyes 28 patients with NTG 25 normal subjects matched age, refractive errors, systemic blood pressure, central corneal thickness were evaluated. OCT-A was used to measure whole image vessel density, inside disc peripapillary density; using LSFG, mean blur rate (MBR) optic nerve head (ONH) area (MBR A ), MBR V )...
Purpose: To investigate the ocular and systemic factors related to glaucoma be adjusted for interindividual comparison of blood flow measurement results by laser speckle flowgraphy (LSFG) obtained from optic nerve head (ONH) in normal Japanese individuals. Methods: A multicenter, prospective cross-sectional study was conducted. The ONH tissue-area vessel-area mean blur rate (MT MV) were evaluated using LSFG structural parameters planimetric methods. Multivariate linear mixed-effects modeled...
To assess the relationship between macular ganglion cell complex and outer retinal thicknesses.Case-control study.Forty-two normal eyes 91 with primary open-angle glaucoma were studied.Spectral-domain optical coherence tomography (RTVue-100) was used to measure thickness. Ganglion thickness ratio also calculated.The relationships thicknesses evaluated.There a positive correlation in group (r = 0.53, P < 0.001 r 0.42, 0.001, respectively). In that respect, there no both groups -0.07, 0.657,...
Purpose . To evaluate the relationships among optic nerve head (ONH) area, macular ganglion cell complex (mGCC) thickness, circumpapillary retinal fiber layer (cpRNFL) and visual field defects in patients with primary open angle glaucoma (POAG). Methods This retrospective study included 90 eyes of POAG. The ONH rim mGCC cpRNFL thickness were measured using optical coherence tomography. Mean deviation (MD) was standard automated perimetry. clinical factors including age, refraction, MD...
Although reduction in intraocular pressure (IOP) is the principle of glaucoma treatment, impaired ocular blood flow believed to play a role progression glaucoma. This study evaluated effect treatment on pulse waveforms for optic nerve head (ONH) microcirculation patients with Fifty-one subjects were included basis administered, which involved instillation prostaglandin (PG) analogs (PG group; n = 28) or trabeculectomy (trabeculectomy 23). ONH flow, represented by mean blur rate (MBR T ) and...
Purpose. We evaluated the association between optic nerve head (ONH) microcirculation and macular ganglion cell complex (mGCC) thickness in patients with untreated normal tension glaucoma (NTG) a hemifield defect. Methods. The medical records of 47 NTG were retrospectively reviewed. Laser speckle flowgraphy was used to obtain mean blur rate (MBR), relative measure blood flow. Average total deviation (TD), mGCC, circumpapillary retinal fiber layer (cpRNFL) also analyzed. Results. All...
Purpose: To evaluate the relationship between macular vessel density and photopic negative response (PhNR) amplitude of focal electroretinograms (ERGs) in patients with early-stage normal tension glaucoma (NTG). Materials Methods: This prospective cross-sectional study included a total 42 subjects NTG. Optical coherence tomography angiography was used to measure density, ERGs were elicited by white light stimulus (30 cd/m2) background (1.5 cd/m2). The PhNR measured from peak b-wave trough....
Purpose Few optical coherence tomography (OCT) studies have investigated outer retinal thickness including the photoreceptor layer in glaucoma. We measured changes macular thicknesses using OCT patients with glaucoma an average follow-up of 2.9 ± 0.8 years. Methods A total 39 eyes primary open-angle were analyzed. The RTVue-100 was used to measure retinal, ganglion cell complex, and circumpapillary nerve fiber thicknesses, global loss volume, focal volume. Using paired t test, baseline...
Purpose: To evaluate efficacy and safety of ripasudil for 1 year in addition to or replacing existing treatment regimens. Methods: We retrospectively reviewed the medical records 128 eyes glaucoma patients who were prescribed as an a switch from their preexisting antiglaucoma instillations. investigated rate factors discontinuation intraocular pressure (IOP) reduction. Results: Almost half (60 eyes) discontinued before mark, while remaining completed treatment. The lack development adverse...
Purpose . To investigate factors related to a right-left difference in visual field defect untreated normal tension glaucoma (NTG). Methods The medical records of 92 patients with NTG were reviewed. Ocular blood flow was evaluated laser speckle flowgraphy, and the mean blur rate (MBR) at optic nerve head analyzed. Relationships between differences deviation (MD), intraocular pressure, MBR, spherical equivalent, central corneal thickness, ocular perfusion pressure using Spearman’s rank...
Background: OCT angiography (OCTA) and laser speckle flowgraphy (LSFG) are novel noninvasive imaging modalities which could evaluate fundus blood flow quantitatively. However, the role of OCTA LSFG as diagnostic tools has not been widely investigated. Previous reports indicated that NO, reduced by hyperglycemia, exerts a key for autoregulation retinal flow. We designed this study to in hyperglycemic DM. Method: 10 patients with extreme hyperglycemia at our outpatient clinic...
We aimed to investigate factors related superior and inferior hemifield defects in primary open-angle glaucoma (POAG). Sixty-seven subjects with newly diagnosed, untreated POAG underwent optical coherence tomography (OCT) of the disc area, macular ganglion cell complex (mGCC), circumpapillary retinal nerve fiber layer (cpRNFL) thickness within 6 months visual field (VF) test. Based on VF OCT results, 40 had a 27 an hemifield defect. Clinical data including acuity, refractive error, hemorrhage,...