- Lymphoma Diagnosis and Treatment
- Viral-associated cancers and disorders
- Geological and Geochemical Analysis
- Geochemistry and Geologic Mapping
- Complex Network Analysis Techniques
- Mechanical and Optical Resonators
- Methane Hydrates and Related Phenomena
- T-cell and Retrovirus Studies
- Immune Cell Function and Interaction
- CCD and CMOS Imaging Sensors
- Software Testing and Debugging Techniques
- Hydrocarbon exploration and reservoir analysis
- Optimal Power Flow Distribution
- Advanced MEMS and NEMS Technologies
- Caching and Content Delivery
- Microgrid Control and Optimization
- Acoustic Wave Resonator Technologies
- Infrared Target Detection Methodologies
- earthquake and tectonic studies
- Epigenetics and DNA Methylation
- Machine Fault Diagnosis Techniques
- Cancer-related gene regulation
- Advanced Computational Techniques and Applications
- Software Engineering Research
- Chronic Lymphocytic Leukemia Research
First Affiliated Hospital of Wannan Medical College
2010-2024
Sun Yat-sen University
2020-2024
Sun Yat-sen University Cancer Center
2020-2024
Beijing University of Chemical Technology
2024
Georgetown University Medical Center
2024
Georgetown University
2024
Sichuan University
2024
First Affiliated Hospital of Zhengzhou University
2015-2023
China Nonferrous Metal Mining (China)
2023
Zhejiang University
2012-2021
Four of nine tetraalkylammonium-based amino-acid ionic liquids prepared in this work show lower viscosities than all amino acid-based found the literature and their reversible CO2 absorption approaches 0.5 mol per liquid.
Abstract KRAS mutations are highly prevalent in a wide range of lethal cancers, and these mutant forms play crucial role driving cancer progression conferring resistance to treatment. While there have been advancements the development small molecules target specific mutants, presence undruggable mutants emergence secondary continue pose challenges clinical treatment KRAS-mutant cancers. In this study, we developed novel molecular tool called tumor-targeting degrader (TKD) that effectively...
Six acid salt ionic liquids (ASILs), triethylbutylammonium dicarboxylates, have been synthesized to act as green materials for SO2 capture. The experimental results reveal that the ASILs can trap reversibly and chemically with a large capacity of 0.112 up 0.232 (mass ratio) at 15.5 kPa 0.374 0.456 100 40 °C. Two these are interestingly found low viscosity enables fast mass transfer SO2. A reaction mechanism is proposed explain chemical absorption based on FTIR spectra structural calculations...
To investigate the expression of polo-like kinase 1 protein (PLK1) and its phosphorylation level (p-PLK1) in extranodal NK/T cell lymphoma (NKTCL) their correlation with clinical characteristics prognosis.We collected 40 cases NKTCL (referred to as experimental group), which received diagnoses at First Affiliated Hospital Zhengzhou University between January 2018 October 2022. Concurrently, we assembled a control group, including 20 afflicted nasopharyngeal mucosal lymphoid hyperplasia...
Background: Innovative treatment strategies for early-stage breast cancer (BC) are urgently needed.Tumors originating from mammary ductal cells present an opportunity targeted intervention.Methods: We explored intraductal therapy via natural nipple openings as a promising non-invasive approach early BC.Using functional Near-infrared II (NIR-II) nanomaterials, specifically NIR-IIb quantum dots conjugated with Epep polypeptide cell targeting, we conducted in situ imaging and photothermal...
The Tulasu Basin is an important epithermal gold ore cluster situated in the Boluokenu Polymetallic Belt, Western Tianshan, China. Axi Au, Tabei Pb–Zn, and Tawuerbieke Au deposits this basin represent different types of mineralization. These are products same tectonic‐magmatic‐hydrothermal event, related to southward subduction North Tianshan Ocean beneath Yili‐Central Plate during Late Devonian Early Carboniferous. spatial relationships, preservation levels, evolution three still debated....
Abstract To compare the efficacy and safety of radiotherapy (RT) chemotherapy pegaspargase, gemcitabine, cisplatin dexamethasone (DDGP) combined with RT in newly diagnosed stage I‐II natural killer/T‐cell lymphoma (NKTL), we designed a randomized, controlled, open‐label, multicenter clinical trial. Data from 65 NKTL patients whose diagnoses were confirmed using immunohistochemistry enrolled January 2011 to December 2013 First Affiliated Hospital Zhengzhou University. Patients randomly...
In a social network, users hold and express positive negative attitudes (e.g. support/opposition) towards other users. Those exhibit some kind of binary relationships among the users, which play an important role in network analysis. However, those are likely to be latent as scale increases. The essence predicting have recently began draw researchers' attention. this paper, we propose machine learning algorithm for networks inspired by structural balance theory status theory. More...
Abstract Supramolecular mechanophores typically exhibit much lower mechanical strengths than covalent counterparts, with usually around 100 pN, which is significantly the nN‐scale strength of bonds. Inspired by slow dissociation kinetics cucurbit[7]uril (CB[7])–hexanoate‐isoquinoline (HIQ) complex, we discovered that charge–dipole repulsion can be utilized to create strong supramolecular mechanophores. When activated at its −COO − state, CB[7]−HIQ complex exhibits a high ~700 comparable weak...
A probability-one homotopy method for standard and least-square partial pole assignment problems is presented in this paper. The suggested enjoys superior theoretical properties it very reliable. Implementation innovations, including the development of an efficient algorithm computing second order derivatives eigenvalues, rescaling eigenvalue tracking, are reported detail. Simulation results ten test systems East China power system with 465 machines 3296 buses described, showing that a...
Online users nowadays are facing serious information overload problem. In recent years, recommender systems have been widely studied to help people find relevant information. Adaptive social recommendation is one of these in which the connections online networks optimized for propagation so that can receive interesting news or stories from their leaders. Validation such adaptive methods literature assumes uniform distribution users' activity frequency. this paper, our empirical analysis...
In this study, the stage subsequent to filling mining is selected as background, and cemented tailings backfill serves research object. Given effects of layer effect, top load, lateral pressure coefficient, so forth, a safety factor calculation model in large depth–width ratio stopes developed accordance with Mohr–Coulomb failure criterion, which compared models proposed by other scholars. Lastly, characteristics effect exerted wide variety factors are discussed. As indicated results, (1)...
The present study aimed to use magnetic resonance (MR) explore the dynamic changes of ischiofemoral space (IFS) under triaxial motion hip joint and verify clinical test mechanism for impingement (IFI).A prospective design was used screen 37 patients with clinically confirmed IFI, which included a total 67 lateral hips, 39 healthy controls 69 hips. A MR examination performed in positions designed by simulated IFI (adduction, adduction 30° external rotation, internal supine flexion, prone...
Abstract Natural killer/T-cell lymphoma (NKTCL) in children and adolescents is a rare type of T/NK cell neoplasms. The aim the present study was to analyze clinicopathological genetic features this entity lymphoma. We evaluated clinical, histopathological molecular 22 young people with NKTCL, including 15 males 7 females, median age years. results revealed that nasal site most involved region while non-nasal sites were observed 27.3% out all cases. tumor cells composed small‑sized large 19...