A5007505052- HIV/AIDS Research and Interventions
- Adolescent Sexual and Reproductive Health
- HIV Research and Treatment
- Child and Adolescent Psychosocial and Emotional Development
- Mental Health Treatment and Access
- HIV-related health complications and treatments
- Maternal Mental Health During Pregnancy and Postpartum
- Autism Spectrum Disorder Research
- Family Caregiving in Mental Illness
- Mosquito-borne diseases and control
- Dementia and Cognitive Impairment Research
- Aging, Elder Care, and Social Issues
- Poverty, Education, and Child Welfare
- Intensive Care Unit Cognitive Disorders
- Nail Diseases and Treatments
- Healthcare professionals’ stress and burnout
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- HIV, Drug Use, Sexual Risk
- HIV/AIDS drug development and treatment
- Cognitive Functions and Memory
- Antifungal resistance and susceptibility
- Mental Health Research Topics
- Stress and Burnout Research
- Health, Environment, Cognitive Aging
- Medication Adherence and Compliance
University of Zimbabwe
2015-2025
Trinity College Dublin
2024
Primary Health Care
2022
Global Brain Health Institute
2021
University of California, San Francisco
2021
Using a pilot trial design in an HIV care clinic Zimbabwe, we randomised 32 adults with poor adherence to antiretroviral therapy and at least mild depression either six sessions of Problem-Solving Therapy for (PST-AD) delivered by counsellor, or Enhanced Usual Care (Control). Acceptability PST-AD was high, as indicated frequency session attendance through qualitative analyses exit interviews. Fidelity >80% the first two but fidelity component dropped 4. Contamination occurred, that seven...
Abstract Objective To document the lived experiences of people with both poor mental health and suboptimal adherence to antiretroviral therapy in high HIV prevalence settings. Methods In‐depth qualitative interviews were conducted 47 (female = 31) ‐positive adults who scored above cut‐point on a locally validated scale for common disorders (CMDs). Purposive sampling was used recruit participants evidence adherence. Six additional key informant 6) healthcare workers. Data collected analysed...
Few evidence-based interventions to improve adherence antiretroviral therapy have been adapted for use in Africa. We selected, culturally and tested the feasibility of a cognitive-behavioural intervention delivery clinic setting Harare, Zimbabwe. The was evaluated using mixed-methods assessment, including ratings provider fidelity delivery, qualitative assessments individual semi-structured interviews with counsellors (n=4) patients (n=15). feasible acceptable when administered 42 resulted...
In Ghana, one in three adolescents are at risk of experiencing depression. However, access to treatment is limited due the poor integration mental health services into primary healthcare systems. Evidence-based interventions, especially psychological therapies and antidepressant medication, can restore functioning for depressed youth. Ghana currently runs a policy free Senior High Secondary Education aims implement national adolescent policy. component poorly developed. Our formative...
HIV affects the central nervous system resulting in associated neurocognitive impairment (NCI) approximately 50% of people living with HIV. It typically memory, learning, working fine motor skills, speed information processing, verbal fluency and executive functioning cognitive domains. NCI can affect adherence to antiretroviral therapy (ART), employability, driving ability activities daily living. is not routinely screened for Zimbabwe, burden known this setting. The objectives study were:...
Abstract Background Adolescents and young adults living with HIV in sub Saharan Africa are at high risk of poor adherence to antiretroviral therapy (ART) virologic failure (VF). Methods We conducted a randomized control trial among adolescents on ART VF assess the effectiveness community-based peer support intervention aimed improving VF. Viral load (VL) levels were obtained 12, 24 36 weeks. A subset participants had baseline drug resistance (HIVDR) genotyped using Sanger sequencing. Results...
Our study's primary objective was to compare 1-year survival rates between serum cryptococcal antigen (sCrAg)-positive and sCrAg-negative HIV-positive individuals with CD4+ cell counts less than 100 cells/μl without symptoms of meningitis in Zimbabwe.This a prospective cohort study.Participants were enrolled as either sCrAg-positive or followed up for 52 weeks less, death the outcome. Lumbar punctures recommended all sCrAg-positives inpatient management intravenous amphotericin B high-dose...
Introduction Non-adherence to antiretroviral therapy (ART) is the main cause of viral non-suppression and its risk increased by depression. In countries with high burden HIV, there a lack trained professionals deliver depression treatments. This paper describes protocol for 2-arm parallel group superiority 1:1 randomised controlled trial, test effectiveness cost TENDAI stepped care task-shifted intervention depression, ART non-adherence HIV suppression delivered lay interventionists. Methods...
Background The beliefs that patients hold about their medicines are known to influence treatment adherence. This study’s objective was explore and identify specific antiretroviral (ART) from human immunodeficiency virus (HIV) positive in Zimbabwe. Methods In-depth qualitative interviews were conducted with 21 (female = 9; 42.9%) purposively sampled HIV-positive adults attending an urban HIV clinic. All participants had been prescribed ART for at least one month. Two additional key informant...
Objective: Appropriate adjustments to normative data for neuropsychological (NP) tests are imperative their equitable use in brain health practices. Age and education known be strong predictors of test performance. In settings where validated not available, common practice has been adapt apply them similar fashion as they were developed. However, demographic cannot assumed de facto universal strength domain associations. For example, South Africa (SA) Zimbabwe neighboring countries with some...