A5041642251- Bone health and osteoporosis research
- Medical Imaging Techniques and Applications
- Bone and Joint Diseases
- Vitamin D Research Studies
- Public Administration and Political Analysis
- Reliability and Agreement in Measurement
- Bioinformatics and Genomic Networks
- Food composition and properties
- Medical Imaging and Analysis
- Bone health and treatments
- Probiotics and Fermented Foods
- Climate Change and Health Impacts
- Law and Political Science
- Microbial Metabolites in Food Biotechnology
- Data Quality and Management
- Dental Radiography and Imaging
- Radiation Dose and Imaging
- Hip and Femur Fractures
- Infrared Thermography in Medicine
- Estrogen and related hormone effects
- Body Composition Measurement Techniques
- Innovation, Technology, and Society
- Meta-analysis and systematic reviews
- Law, AI, and Intellectual Property
- Flexible and Reconfigurable Manufacturing Systems
University Hospital Schleswig-Holstein
2004-2013
University of Lübeck
2004-2013
Schmerzklinik Kiel
2003-2004
Abstract We compared the performance of five QUS devices with DXA in a population-based sample 2837 women. All approaches discriminated women and without osteoporotic vertebral fractures. calcaneus performed as well central DXA. Introduction: Quantitative ultrasound (QUS) methods have found widespread use for assessment bone status osteoporosis, but their optimal remains to be established. To determine current direct comparison DXA, we initiated large investigation, Osteoporosis Ultrasound...
Abstract We introduce a method for microstructural analysis of vertebral trabecular bone in vivo based on HRCT. When applied to monitor teriparatide treatment, changes structural variables exceeded and were partially independent volumetric BMD. Introduction: Monitoring osteoporosis therapy solely densitometry is insufficient assess anti-fracture efficacy. Assessing microstructure therefore importance. studied whether it possible effects BMD by high-resolution CT (HRCT). Materials Methods: In...
Abstract The effect of season on bone turnover is controversial. No information available seasonality new serum markers resorption. In this study, we have been unable to confirm findings a marked wintertime increase in formation and resorption within the general population. Seasonality was assessed by cosinor analysis. Introduction: We investigated seven longitudinal study (six men six premenopausal women; age, 24–44 years) separate large population-based multicenter European (n = 2780...
Information on the pathophysiology of glucocorticoid-induced osteoporosis (GIO) is limited, since its clinical picture often reflects a combined effect glucocorticoids (GC) and treated systemic disease (i.e., inflammation immobility). In 50 healthy adult (30-mo-old) primiparous Göttingen minipigs, we studied short-term (8 mo, n = 30) long-term (15 10) GC bone mineral metabolism longitudinally cross-sectionally compared with control group ( 10). All animals treatment received prednisolone...
Calcium and vitamin D deficiency impairs bone health may cause rickets in children osteomalacia adults. Large animal models are useful to study experimental osteopathies associated metabolic changes. We intended modulate status induce nutritional minipigs. The control group ( n = 9) was fed a semisynthetic reference diet with 6 g calcium 6,500 IU 3 /kg the 10) same but only 2 calcium/kg without D. After 15 months, deficient animals were negative balance, having lost mineral density...
In their letter, Nguyen et al. review some of the well-established limitations using odds ratios (ORs). However, we believe that following critical statements regarding our manuscript are based on an inappropriate representation position put forward in paper,1 part by disregarding key paper. We also disagree with main conclusion risk assessment is little use for individual. At outset, explain ORs. Notwithstanding limitations, ORs represent method choice expressing associations disease...
To the Editor: We thank Dr Seibel and colleagues for their interest in our paper.1 reiterate conclusion that seasonal change is unlikely to be an important pre-analytical factor confounding use of markers bone turnover clinical practice. et al. seem agree with this. further studies relevant populations are required confirm (or indeed refute) conclusion. It perhaps worth restating topic debate because we most comments The debatable issue not whether season has any significant impact on at...
Trabecular networks of cancellous bone show complex and stochastic characteristics, which have to be modelled in an adequate way determine pathological changes the network induced by osteoporosis. The analysis complexity may handled use Markov Theory, is based on local interactions a set elements thus can applied trabecular networks. conditional entropy investigated as potential measure complexity, estimates order structure provides means for classification healthy versus osteoporotic...
Article Evaluation quantitativer Ultraschallverfahren zur Bestimmung der Knocheneigenschaften menschlicher Phalangen mit Hilfe von hochauflösender Magnetresonanzbildgebung, Mikro Computer Tomographie und Schallausbreitungssimulation was published on January 1, 2000 in the journal Biomedical Engineering / Biomedizinische Technik (volume 45, issue s1).
Quantitative Ultrasound (QUS) methods are useful in the assessment of bone status. Nevertherless, a detailed understanding ultrasound propagation through is important for accurate interpretation QUS results. A new PC-based software simulation (Wave 2000, Cyberlogic, NY) might be helpful to understand interaction with bone. We evaluated validity this by comparing measured and calculated results obtained on human finger phalanges. The transverse transmission sound wave phalanx was depicted.