A5013852779- Probiotics and Fermented Foods
- Oral health in cancer treatment
- Fish biology, ecology, and behavior
- Fish Biology and Ecology Studies
- Aquaculture Nutrition and Growth
- Gut microbiota and health
- Environmental Sustainability and Education
- Reproductive biology and impacts on aquatic species
- Fish Ecology and Management Studies
- Antimicrobial Peptides and Activities
- Animal Genetics and Reproduction
- Meat and Animal Product Quality
- Gastrointestinal motility and disorders
- Viral gastroenteritis research and epidemiology
- Escherichia coli research studies
- Salivary Gland Disorders and Functions
- Bacteriophages and microbial interactions
- Pediatric health and respiratory diseases
- Effects of Environmental Stressors on Livestock
- Animal Nutrition and Physiology
- Transgenic Plants and Applications
- Head and Neck Cancer Studies
- Tailings Management and Properties
- Oral and gingival health research
- Landfill Environmental Impact Studies
Federal Center for Technological Education of Minas Gerais
2016-2023
Universidade Federal de Minas Gerais
2016-2022
Faculdade de Ciências Médicas de Minas Gerais
2020
Centro Universitário de Belo Horizonte
2018-2019
Universidade Federal de Lavras
2010-2018
Aim: This study aims to verify the antibacterial and antibiofilm action of cell-free spent medium (CFSM) from four lactic acid bacteria with potential probiotic characteristics (Lactiplantibacillus plantarum, Lactobacillus acidophilus, johnsonii, delbrueckii) against two Pseudomonas aeruginosa strains. Main methods: The minimum inhibitory concentration (MIC) bactericidal (MBC) CFSM, activity by analysing formation inhibition zones, planktonic cultures were determined. Whether an increase in...
Mucositis is a cytotoxic side effect caused by chemotherapy drugs, such as 5-Fluorouracil (5-FU), being serious clinical issue. Lactobacillus spp. could be helpful strategy to alleviate 5-FU chemotherapy-caused intestinal damage, due their ability contribute homeostasis through improvement of microbiota balance and immunomodulation. In this work we evaluated the delbrueckii subsp. lactis CIDCA 133 fermented milk in 5-FU-induced experimental mucositis. Intestinal histology, permeability...
Intestinal mucositis is a commonly reported side effect in oncology practice. Probiotics are considered an excellent alternative therapeutic approach to this debilitating condition; however, there safety questions regarding the viable consumption of probiotics clinical practice due risks systemic infections, especially immune-compromised patients. The use heat-killed or cell-free supernatants derived from probiotic strains has been evaluated minimize these adverse effects. Thus, work...
Intestinal mucositis promoted by the use of anticancer drugs is characterized ulcerative inflammation intestinal mucosa, a debilitating side effect in cancer patients undergoing treatment. Probiotics are potential therapeutic option to alleviate due their effects on epithelial barrier integrity and anti-inflammatory modulation. This study investigated health-promoting impact Lactobacillus delbrueckii CIDCA 133 modulating inflammatory markers protect mucosa from 5-fluorouracil-induced damage....
Wound healing is a complex dynamic physiological process in response to cutaneous destructive stimuli that aims restore the cutaneous' barrier role. Deciphering underlying mechanistic details contribute wound will create novel therapeutic strategies for skin repair. Recently, by using state-of-the-art technologies, it was revealed microbiota interact with immune cells. Strikingly, commensal Staphylococcus epidermidis-induced CD8+ T cells induce re-epithelization of after injury, accelerating...
Alzheimer's disease (AD) is a progressive neurodegeneration characterized by neuron death ending in memory and cognitive decline.A major concern AD research the identification of new therapeutics that could prevent or delay onset disorder, with current treatments being effective only reducing symptoms.In this perspective, use engineered probiotics as therapeutic tools for delivery molecules to eukaryotic cells finding application several disorders.This work introduces strategy treatment...
5-Fluorouracil (5-FU) is an antineoplastic drug that causes, as a side effect, intestinal mucositis, acute inflammation in the small bowel. The Heat Shock Protein (Hsp) are highly expressed inflammatory conditions, developing important role immune modulation. Thus, they potential candidates for treatment of diseases. In mucositis mouse model, present study aimed to evaluate beneficial effect oral administration milk fermented by Lactobacillus delbrueckii CIDCA 133 (pExu:hsp65), recombinant...
Lactococcus lactis is well documented as a promising candidate for development of novel oral live vaccines. It has been broadly engineered heterologous expression, plasmid expression vector delivery, directly inside eukaryotic cells, DNA vaccine, or therapeutic vehicle. This work describes the characteristics new plasmid, pExu (extra chromosomal unit), delivery using L. and evaluates its functionality both by in vitro vivo assays. exhibits following features: (1) theta origin replication (2)...
Lactobacillus delbrueckii subsp. lactis CIDCA 133 (CIDCA 133) has been reported as a potential probiotic strain, presenting immunomodulatory properties. This study investigated the possible genes and molecular mechanism involved with profile of through genomic approach associated in vitro vivo analysis. Genomic analysis corroborates species identification carried out by classical microbiological method. Phenotypic assays demonstrated that strain could survive acidic, osmotic, thermic...
The microencapsulation process of bacteria has been used for many years, mainly in the food industry and, among different matrixes used, sodium alginate stands out. This matrix forms a protective wall around encapsulated bacterial culture, increasing its viability and protecting against environmental adversities, such as low pH, example. aim present study was to evaluate both vitro vivo, capacity encapsulation maintain viable lactic acid (LAB) strains longer period time verify if they are...
In medicine, the 20th century was marked by one of most important revolutions in infectious-disease management, discovery and increasing use antibiotics.However, their indiscriminate has led to emergence multidrug-resistant (MDR) bacteria.Drug resistance other factors, such as production bacterial biofilms, have resulted high recurrence rates diseases.Bacterial vaginosis (BV) syndrome is prevalent vaginal condition women reproductive age, M.O.Almeida et al. 2 leading considerable...
A piracanjuba (Brycon orbignyanus Valenciennes, 1849) é uma espécie de peixe migratória, ameaçada extinção. O objetivo do presente estudo foi determinar a dose inseminante na fertilização artificial ovócitos piracanjuba. Para isso, utilizou-se delineamento em blocos casualizados, com quatro tratamentos e três repetições. Três casais piracanjuba, selecionados dos tanques reprodutores da Estação Ambiental Itutinga (EAI - CEMIG), no período piracema 2006/2007, receberam aplicação hormônio...
This study aimed to describe the seasonal variation of condition factor (K) correlated with gonadossomatic (GSI) and hepatossomatic index (HSI) Leporinus obtusidens (Valenciennes, 1837), collected downstream Hidroelectric Power Station Funil, state Minas Gerais, Brazil, evaluate if these indices can indicate reproductive period this species. The animals were captured between September/2006 August/2007 grouped seasonally. length weight 110 individuals measured calculate K, liver was...
This study evaluated the reproductive dynamics and gonadal morphology of piaparas (Leporinus obtusidens) captured downstream from Funil Hydroelectric Power Station. The 107 were monthly Sep 2006 to Aug 2007. data stratified among seasons evaluate gonad maturation period was determined by assessing gonadosomatic index, hepatosomatic abdominal fat index (AFI), weight:length ratio, condition factor sexual proportion. lasted winter summer (Jul-Mar) in females spring autumn (Sept-Jun) males. AFI...
An experiment was conducted during 60 days with forty pacu males fed diets supplemented increasing concentrations of ractopamine (0.00, 11.25, 22.50, 33.75, and 45.00 mg kg−1). Eight fish were evaluated for each experimental diet. Performance survival rate the measured. At end experiment, blood collected to determine levels cortisol, triacylglycerol, protein. Moreover, liver activities glucose-6-phosphate dehydrogenase malic enzymes. The fillets chemical composition, histologic cuts analyzed...