- Muscle activation and electromyography studies
- Corneal surgery and disorders
- Elasticity and Material Modeling
- Cardiomyopathy and Myosin Studies
- Ophthalmology and Visual Impairment Studies
- Sports injuries and prevention
- Hernia repair and management
- Glaucoma and retinal disorders
- Muscle Physiology and Disorders
- Total Knee Arthroplasty Outcomes
- Ocular Surface and Contact Lens
- Intraocular Surgery and Lenses
- Freezing and Crystallization Processes
- Fatigue and fracture mechanics
- Force Microscopy Techniques and Applications
- Meat and Animal Product Quality
- Sports Performance and Training
- Advanced Sensor and Energy Harvesting Materials
- Tendon Structure and Treatment
- Prosthetics and Rehabilitation Robotics
- Food Drying and Modeling
- Food Supply Chain Traceability
- Corneal Surgery and Treatments
- Induction Heating and Inverter Technology
- Cellular Mechanics and Interactions
Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine
2015-2025
Universidad de Zaragoza
2014-2025
Bioengineering (Switzerland)
2020-2023
Applied Microengineering Limited (United Kingdom)
2023
Institute of Engineering
2010
Centro de Investigación Biomédica en Red
2010
The goal of the study is to introduce a generic, versatile biomechanical model that aims reproduce dynamic wobbling phenomenon. A systematic strategy used, which includes a) capturing in vivo data on group healthy volunteers, b) analyzing changes Purkinje images over time, and c) performing combined optical simulations develop might be useful for understanding mechanical behavior lens during its influence ocular dynamics. Examples patterns six measured eyes were presented, parameters...
This study addresses a crucial knowledge gap by investigating the impact of intraocular pressure (IOP) on wobbling characteristics crystalline lens in an ex vivo setting. It utilizes previous validated computational porcine eye models, which offer anatomical and physiological similarities to human eye. These models incorporate fluid-structure interaction (FSI) simulate mechanical between fluids solid structures. Simulations were conducted under constant properties boundary conditions,...
Keratoconus is a progressive ocular disorder affecting the corneal tissue, leading to irregular astigmatism and decreased visual acuity. The architectural organization of tissue altered in keratoconus, however, data from ex vivo testing biomechanical properties keratoconic corneas are limited it unclear how their results relate true mechanical vivo. This study explores through numerical simulations non-contact tonometry (NCT) reproducing clinical test Corvis ST device. Three sensitivity...
This paper describes a method designed to model the repaired herniated human abdomen just after surgery and examine its static mechanical response maximum intra-abdominal pressure provoked by physiological movement (standing cough). The is based on real geometry of bearing large incisional hernia with several anatomical structures differentiated MRI. To analyze outcome repair, surgical procedure was simulated modeling prosthesis placed over hernia. Three meshes different properties were...
Abstract Purpose To reproduce human in vivo accommodation numerically. For that purpose, a finite element model specific for 29‐year‐old subject was designed. Once the proposed numerical validated, decrease accommodative amplitude with age simulated according to data available literature. Methods In contrast previous studies, non‐accommodated eye condition reference configuration. Consequently, two aspects were specifically highlighted: contraction of ciliary muscle, which by continuum...
The objective of this study was to develop and validate a numerical model adequately simulate the double-sided pan cooking beef in domestic environment. proposed takes into account heat flow from meat moisture transfer, simultaneously with deformation. considers swelling pressure gradient caused by shrinkage fibers connective tissue due denaturation proteins loss water holding capacity during cooking. results were successfully verified experimental data central temperature weight recorded...
Abstract The purpose of this study was to investigate how the mechanical properties and geometry lens influence changes in shape during accommodation. To do so, ex vivo stretching tests isolated were simulated via finite element analysis. In these tests, is stretched from accommodated state non-accommodated state. Several key characteristics studied: stiffness gradient material, distribution capsule thickness, material comprising lens, nucleus cortex, two different age-related geometries (17...
Achilles tendon rupture is a frequent injury with an increasing incidence. After clinical surgical repair, aimed at suturing the stumps back into their original position, repaired often plastically deformed and mechanically less strong than pre-injured tissue, muscle fatty degeneration contributing to function loss. Despite outcomes, pre-clinical research has mainly focused on structural lack of knowledge regarding progression from its consequences degenerative/regenerative processes...
Mechanical stimulation affects the evolution of healthy and fractured bone. However, effect applying cyclical mechanical stimuli on bone healing has not yet been fully clarified. The aim present study was to determine influence a high-frequency low-magnitude displacement fragments bone-healing process. This subject is studied experimentally computationally for sheep long On one hand, mathematical computational indicates that at high frequencies can stimulate accelerate process chondrogenesis...
The food industry is shifting toward automated and customized processes, leading to the emergence of smart cooking devices that improve outcomes. However, these can be invasive, costly, only applicable certain foods. To address issues, a noninvasive digital twin monitors during using common frying pan with temperature sensor weighing scale proposed. A case study for French crêpe presented, in which we developed neural network trained on over 400,000 simulation data points. results show...
The process of lens shape change in the eye to alter focussing (accommodation) is still not fully understood. Modelling approaches have been used complement experimental findings order determine how constituents accommodative influence lens. An unexplored factor modelling role software on results simulated change. Finite element models were constructed both Abaqus and Ansys using biological parameters from measurements refractive index two 35-year-old lenses. effect zonular insertion was...