A5008642780- Telomeres, Telomerase, and Senescence
- Molecular Biology Techniques and Applications
- Immune Cell Function and Interaction
- Bacterial Identification and Susceptibility Testing
- T-cell and B-cell Immunology
- Advanced biosensing and bioanalysis techniques
- Gut microbiota and health
- Biosensors and Analytical Detection
- CAR-T cell therapy research
National University of Singapore
2020-2022
Digital real-time PCR assay rapidly measures single telomere lengths and uncovers maintenance mechanisms in cancer.
During the past decade, breakthroughs in sequencing technology have provided basis for studies of myriad ways which microbial communities and on human body influence health disease. In almost every medical specialty, there is now a growing interest accurate quantitative profiling microbiota use diagnostic therapeutic applications. However, current next-generation approach microbiome costly, requires laborious library preparation, challenging to scale up routine diagnostics. Split, Amplify,...
SUMMARY Lymphocyte biology research commonly involves purification of lymphocyte subpopulations by fluorescence-activated cell sorting (FACS) or immunomagnetic separation (IMS), both which typically rely on antibody labeling validated markers. Methods enabling label-free segregation would be invaluable with regard to less-perturbation, simplicity and cost-effectiveness. Here, we introduce TRuST, a approach for T r econstitution u sing s ide-scat t er (SSC). TRuST-sorted SSC low cells enrich...