A5078999453- Pharmaceutical and Antibiotic Environmental Impacts
- Antibiotic Resistance in Bacteria
- Microbial Community Ecology and Physiology
- Antibiotic Use and Resistance
- Environmental DNA in Biodiversity Studies
- Magnetism in coordination complexes
- Lanthanide and Transition Metal Complexes
- Genomics and Phylogenetic Studies
- Water Treatment and Disinfection
- Marine Ecology and Invasive Species
- Organic and Molecular Conductors Research
- Vibrio bacteria research studies
- Aquaculture disease management and microbiota
- Fecal contamination and water quality
- Linguistic Variation and Morphology
- Chemotherapy-related skin toxicity
- Gut microbiota and health
- Polar Research and Ecology
- Biosensors and Analytical Detection
- Bladder and Urothelial Cancer Treatments
- Advanced Proteomics Techniques and Applications
- Antibiotics Pharmacokinetics and Efficacy
- Cancer Treatment and Pharmacology
- Nanoparticle-Based Drug Delivery
- Microplastics and Plastic Pollution
Hong Kong Polytechnic University
2024
National University of Singapore
2015-2024
University of California, Los Angeles
2023
Singapore-HUJ Alliance for Research and Enterprise
2022
National Environment Agency
2020
National University Health System
2018
Caritas Medical Centre
2015
Hospital Authority
2015
Duke-NUS Medical School
2013-2014
UNSW Sydney
2006-2011
Abstract While many studies of coral bleaching report on broad, regional scale responses, fewer examine variation in susceptibility among taxa and changes community structure, before, during after individual reefs. Here we detail the response to by a highly disturbed reef site south mainland Singapore major thermal anomaly 2010. To estimate capacity for resistance stress, on: a) overall severity event, b) differences event c) structure one year before bleaching. Approximately two thirds...
ABSTRACT Wastewater discharged from clinical isolation and general wards at two hospitals in Singapore was examined to determine the emerging trends of antibiotic resistance (AR). We quantified concentrations 12 compounds by analysis using liquid chromatography-tandem mass spectrometry (LC-MS/MS), antibiotic-resistant bacteria (ARB), class 1 integrase gene ( intI1 ), 16 genes (ARGs) that confer 10 different clinically relevant antibiotics. A subset 119 isolates were phylogenetically...
The dissemination of antimicrobial resistance (AMR) is an escalating problem and a threat to public health. Comparative metagenomics was used investigate the occurrence antibiotic resistant genes (ARGs) in wastewater urban surface water environments Singapore. Hospital municipal (
Reclaimed water provides a supply alternative to address problems of scarcity in urbanized cities with high living densities and limited natural resources. In this study, wastewater metagenomes from 6 stages treatment plant (WWTP) integrating conventional membrane bioreactor (MBR) were evaluated for diversity antibiotic resistance genes (ARGs) bacteria, relative abundance class 1 integron integrases (intl1). ARGs confering 12 classes antibiotics (ARG types) persisted through the stages,...
Sewage-based surveillance is widely employed to understand the occurrence and distribution of antimicrobial resistance (AMR) in urban community. However, there are limited studies which investigated sewage different sources within The present study used metagenomics decipher AMR profiles five sources: local residence's source, animal migrant workers' clinical source , wastewater treatment plant influent. A core resistome ARGs was found across all samples, accounting for 81.4%-93.3% abundance...
Arabidopsis telomeric repeat binding factors (TRBs) can bind DNA sequences to protect telomeres from degradation. TRBs also recruit Polycomb Repressive Complex 2 (PRC2) deposit tri-methylation of H3 lysine 27 (H3K27me3) over certain target loci. Here, we demonstrate that associate and colocalize with JUMONJI14 (JMJ14) trigger H3K4me3 demethylation at some The trb1/2/3 triple mutant the jmj14-1 show an increased level TRB JMJ14 sites, resulting in up-regulation their genes. Furthermore,...
Indicator organisms and antibiotic resistance were used as a proxy to measure microbial water quality of ballast tanks ships, surface waters in tropical harbor. The survival marine bacteria appeared diminish over longer retention time, with reduction cell viability observed after week based on heterotrophic plate counts. Pyrosequencing 16S rRNA genes showed distinct differences composition harbor waters. had higher abundance operational taxonomic units (OTUs) assigned Cyanobacteria...