A5088241675- Allergic Rhinitis and Sensitization
- Patient Safety and Medication Errors
- Vaccine Coverage and Hesitancy
- Glioma Diagnosis and Treatment
- Asthma and respiratory diseases
- Pharmaceutical Practices and Patient Outcomes
- Respiratory and Cough-Related Research
- Dermatology and Skin Diseases
- Pneumonia and Respiratory Infections
- Microtubule and mitosis dynamics
- Hedgehog Signaling Pathway Studies
- Health Systems, Economic Evaluations, Quality of Life
- Occupational Health and Safety Research
- Respiratory viral infections research
- Oral Health Pathology and Treatment
- Electronic Health Records Systems
- Health Policy Implementation Science
- Problem and Project Based Learning
- Healthcare Policy and Management
- Maternal and fetal healthcare
- Clinical Reasoning and Diagnostic Skills
- Management and Marketing Education
- SARS-CoV-2 and COVID-19 Research
- Neuroscience of respiration and sleep
- Child and Adolescent Health
National Patient Safety Foundation
2020-2025
Johns Hopkins University
2012-2025
Johns Hopkins Medicine
2012-2025
Hospital for Special Surgery
2020-2022
Allen (United States)
2022
Brigham and Women's Hospital
2022
Columbia University
2022
Academic Pediatric Association
2022
ORCID
2021
University of Calgary
2020
Abstract Purpose: BRAF is frequently activated by gene fusion or point mutation in pilocytic astrocytoma, the most common pediatric brain tumor. We investigated functional effect of constitutive activation normal human neural stem and progenitor cells to determine its role tumor induction brain. Experimental Design: The constitutively active BRAFV600E allele was introduced into neurospheres, effects on MAPK (mitogen-activated protein kinase) signaling, proliferation, soft agarose colony...
Although children with low socioeconomic status (SES) have increased risk for sleep-disordered breathing (SDB), their access to subspecialty care is often limited. Polysomnography (PSG) the gold standard diagnostic test used characterize SDB and diagnose obstructive sleep apnea; however, it unknown whether SES impacts timeliness of obtaining PSG surgical treatment adenotonsillectomy (AT).To evaluate impact on timing PSG, surgery AT, loss follow-up SDB.Retrospective cohort analysis conducted...
A novel coronavirus disease, named disease 2019 or COVID-19, which sparked an outbreak in Wuhan, China December 2019, is now a pandemic. The rapid spread of this from one to more than 155 regions worldwide 2.5 months highlights the need for better preparation manage In commentary, we describe how Human Factors and Ergonomics (HFE) can contribute COVID-19 pandemic response. Specifically, provide example HFE methodologies informed workflow redesigns implemented as part preparations academic...
Over the last 15 years, a virtual revolution has taken place in use of Virtual Reality simulation technology for clinical purposes. Shifts social and scientific landscape have now set stage next major movement Clinical with “birth” intelligent humans. Seminal research development appeared creation highly interactive, artificially natural language capable human agents that can engage real users credible fashion. No longer at level prop to add context or minimal faux...
Disclosure of adverse events has become the expectation in medicine and is widely regarded as appropriate path when medical errors occur. Although data are limited on pediatrics, that they occur frequently uncontested. Types rates vary depending care setting patient population. Patients with complex conditions or from historically marginalized groups minoritized communities likely suffer disparate health safety outcomes. Systemic factors, including nonpunitive cultures supportive...
There are considerable gaps in our knowledge of how children develop abstract language. In this paper, we tested the Affective Embodiment Account, which proposes that emotional information is more essential for than concrete conceptual development. We recognition memory 7- and 8-year-old children, as well a group adults, words differed categorically valence (negative, neutral, positive). Word significantly interacted with concreteness hit rates both such effects were only found words. The...
Ankyloglossia refers to a congenitally tight lingual frenulum that limits the motion of tongue. Whether release in neonates improves breastfeeding is not clear. Because many symptoms ankyloglossia overlap those other difficulties, team partnership necessary.
Objective To evaluate follow-up and timing of sleep-disordered breathing diagnosis treatment in urban children referred from primary care. Study Design Retrospective longitudinal cohort analysis. Setting Tertiary health system. Subjects Methods Pediatric outpatients with breathing, care for subspecialty appointment or polysomnography 2014, followed 2 years. Timing appointments, loss to follow-up, severity were main outcomes. Chi-square t-test identified differences polysomnography, surgery,...
Mental health and psychosocial factors play a critical role in clinical outcomes orthopaedic surgery.The biopsychosocial model of disease defines as product physiology, psychology, social and, traditionally, has not been emphasized the care musculoskeletal disease.Improvement postoperative patient satisfaction is incumbent upon screening, recognition, assessment, possible referral patients with high-risk both before after surgical procedure.
Objective. This study assessed safety culture and staff communication with patients limited English proficiency (LEP) to identify system-level approaches increasing interpreter use reducing health care disparities. Methods. An electronic survey 7 focus groups were conducted professionals in pediatrics obstetrics/gynecology. Survey data examined univariate descriptive analysis. Focus group transcripts coded through an iterative consensus process. Results. participants (n = 68) reported less...
Purpose Social and behavioral determinants of health (SBDH) are important factors that affect the individuals but not routinely captured in a structured systematic manner electronic records (EHRs). The purpose this study is to generate recommendations for implementation SBDH data collection EHRs through (1) reviewing conceptual theoretical frameworks (2) eliciting stakeholder perspectives on barriers facilitators using information EHR priorities collection. Method authors reviewed identify...
Bronchiolitis is the leading cause of infant hospitalizations in United States. Despite clinical practice guidelines discouraging utilization non–evidence-based therapies, there continues to be wide variation care and resource utilization. A pre-post physician focused educational intervention was conducted with aims reduce use medical including bronchodilators, among patients admitted for bronchiolitis. Among meeting inclusion criteria (pre: n = 45; post: 47), bronchodilator decreased by 50%...