A5076399844- Health Systems, Economic Evaluations, Quality of Life
- Antibiotic Resistance in Bacteria
- Antimicrobial Resistance in Staphylococcus
- Colorectal Cancer Screening and Detection
- Treatment of Major Depression
- Bacterial Identification and Susceptibility Testing
- Substance Abuse Treatment and Outcomes
- Meta-analysis and systematic reviews
- Nosocomial Infections in ICU
- Antibiotic Use and Resistance
- Bacterial biofilms and quorum sensing
- Legionella and Acanthamoeba research
- Antibiotics Pharmacokinetics and Efficacy
- Health Policy Implementation Science
- Pharmaceutical and Antibiotic Environmental Impacts
- Lung Cancer Diagnosis and Treatment
- Medical Coding and Health Information
- Occupational and environmental lung diseases
- Mycobacterium research and diagnosis
- Diet and metabolism studies
- Pharmaceutical Practices and Patient Outcomes
- Construction Project Management and Performance
- Resilience and Mental Health
- Lung Cancer Treatments and Mutations
- Atrial Fibrillation Management and Outcomes
The Ohio State University
2021-2025
University Medical Center Freiburg
2012-2024
University of North Carolina at Chapel Hill
2015-2024
RTI International
2008-2024
Society of General Internal Medicine
2024
Community Link
2024
University of Freiburg
2006-2022
Cecil College
2008-2022
The Ohio State University Wexner Medical Center
2022
Colorado State University
2020-2022
In recent years, methicillin-resistant Staphylococcus aureus (MRSA) have become a truly global challenge. addition to the long-known healthcare-associated clones, novel strains also emerged outside of hospital settings, in community as well livestock. The emergence and spread virulent clones expressing Panton-Valentine leukocidin (PVL) is an additional cause for concern. order provide overview pandemic, epidemic sporadic strains, more than 3,000 clinical veterinary isolates MRSA mainly from...
ABSTRACT A multilocus sequence typing (MLST) scheme has been developed for Pseudomonas aeruginosa which provides molecular data that are highly discriminatory and electronically portable between laboratories. MLST confirm the from previous studies suggest P. is best described as nonclonal but having an epidemic population. The index of association was 0.17, indicating a freely recombining population; however, there evidence clusters closely related strains or clonal complexes among members...
<h3>Importance</h3> The US Preventive Services Task Force (USPSTF) is updating its 2013 lung cancer screening guidelines, which recommend annual for adults aged 55 through 80 years who have a smoking history of at least 30 pack-years and currently smoke or quit within the past 15 years. <h3>Objective</h3> To inform USPSTF guidelines by estimating benefits harms associated with various low-dose computed tomography (LDCT) strategies. <h3>Design, Setting, Participants</h3> Comparative...
Enterococci have gained significance as the cause of nosocomial infections; they occur food contaminants and also been linked to dental diseases. E. faecalis has a great potential spread virulence well antibiotic resistance genes via horizontal gene transfer. The integration food-borne enterococci into oral biofilm in-vivo observed. Therefore, we investigated determinants 97 isolates from cavity, food, clinical specimens. In addition, phenotypic expression gelatinase cytolysin were tested,...
Article12 February 2020Open Access Transparent process Predicting antimicrobial resistance in Pseudomonas aeruginosa with machine learning-enabled molecular diagnostics Ariane Khaledi Department of Molecular Bacteriology, Helmholtz Centre for Infection Research, Braunschweig, Germany Bacteriology Group, TWINCORE-Centre Experimental and Clinical Hannover, Search more papers by this author Aaron Weimann orcid.org/0000-0003-4597-2471 Computational Biology German Center Research (DZIF), Monika...
Peripheral-blood human T lymphocytes were treated with Staphylococcus aureus alpha-toxin. Membrane permeabilization was assessed by measuring efflux of K+ and Rb+ influx Na+, Ca2+, propidium iodide. Cellular ATP [3H]thymidine incorporation following lectin stimulation measured as parameters for cell viability. Internucleosomal cleavage characteristic programmed death agarose gel electrophoresis quantifying low-molecular-weight, [3H]thymidine-labeled DNA fragments. Nanomolar concentrations...
Objectives: 1-(1-Naphthylmethyl)-piperazine (NMP) has been shown to reverse multidrug resistance (MDR) in Escherichia coli overexpressing RND-type efflux pumps but there are no data on its activity non-fermenters like Acinetobacter. Methods: Antimicrobial susceptibility the absence and presence of NMP and, for comparison, phenyl-arginine-β-naphthylamide (PAβN), another putative pump inhibitor (EPI), was tested laboratory mutant strains with differing intracellular dye accumulation expression...