A5034571649- Antimicrobial Resistance in Staphylococcus
- Bacterial Identification and Susceptibility Testing
- Infective Endocarditis Diagnosis and Management
- Streptococcal Infections and Treatments
- Bacterial biofilms and quorum sensing
- Bacterial Infections and Vaccines
- Antibiotic Use and Resistance
- Reproductive tract infections research
- Physical Education and Pedagogy
- Pneumonia and Respiratory Infections
- Syphilis Diagnosis and Treatment
- Genomics and Phylogenetic Studies
- Antibiotic Resistance in Bacteria
- Inclusion and Disability in Education and Sport
- Sinusitis and nasal conditions
- Parasitic Infections and Diagnostics
- Amoebic Infections and Treatments
- Antifungal resistance and susceptibility
- Antibiotics Pharmacokinetics and Efficacy
- Pneumocystis jirovecii pneumonia detection and treatment
- Sports and Physical Education Research
- Metal complexes synthesis and properties
- Enterobacteriaceae and Cronobacter Research
- Parasitic infections in humans and animals
- Influenza Virus Research Studies
Fiona Stanley Hospital
2015-2024
St Mary's University College
2022-2024
University of the West of England
2024
Texas Christian University
2023
St Mary's University Twickenham London
2011-2021
Primary Children's Hospital
2020
Royal Perth Hospital
2007-2018
Pathwest Laboratory Medicine
2015-2018
Murdoch University
2017
Curtin University
2005-2015
In recent years, methicillin-resistant Staphylococcus aureus (MRSA) have become a truly global challenge. addition to the long-known healthcare-associated clones, novel strains also emerged outside of hospital settings, in community as well livestock. The emergence and spread virulent clones expressing Panton-Valentine leukocidin (PVL) is an additional cause for concern. order provide overview pandemic, epidemic sporadic strains, more than 3,000 clinical veterinary isolates MRSA mainly from...
ABSTRACT Increasing reports of the appearance novel nonmultiresistant methicillin-resistant Staphylococcus aureus MRSA (MRSA) strains in community and spread hospital into are cause for public health concern. We conducted two national surveys unique isolates S. from clinical specimens collected nonhospitalized patients commencing 2000 2002, respectively. A total 11.7% 2,498 15.4% 2,486 2002 were MRSA. Approximately 54% (resistant to less than three nine antibiotics) both surveys. The...
To describe antimicrobial resistance and molecular epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) isolated in community settings Australia.Survey S. isolates collected prospectively Australia-wide between July 2004 February 2005; results were compared with those similar surveys conducted 2000 2002.Up to 100 consecutive, unique clinical from outpatient at each 22 teaching hospital five private laboratories cities all Australian states territories. They characterised by...
An unusual Enterocytozoon bieneusi genotype was found in seven guinea pigs and a 2-year-old child the same household. The genetic uniqueness of parasite, its wide occurrence other community, absence children community suggest possibility zoonotic transmission infection to study child.
ABSTRACT Enterococci are a major cause of health care-associated infections and account for approximately 10% all bacteremias globally. The aim this study was to determine the proportion enterococcal bacteremia isolates in Australia that antimicrobial resistant, with particular emphasis on susceptibility ampicillin glycopeptides, characterize molecular epidemiology Enterococcus faecalis faecium isolates. From 1 January 31 December 2011, 1,079 unique episodes were investigated, which 95.8%...
Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) was first reported in remote regions of Western Australia and is now the predominant MRSA isolated state. The objective this study to determine genetic relatedness Australian CA-MRSA clones within different multilocus sequence type (MLST) clonal clusters providing an insight into frequency S. SCCmec acquisition a region. population genetically diverse consisting 83 unique pulsed-field gel electrophoresis strains from...
ABSTRACT In a longitudinal cohort diarrhea study, girl living in Lima, Peru, and her brother dog were diagnosed with Cryptosporidium canis infections during the same period. Both children had transient diarrhea, but was asymptomatic. This is first report of possible transmission cryptosporidiosis between humans dogs.
Abstract Community-associated methicillin-resistant Staphylococcus aureus (MRSA) was first reported in Western Australia the early 1990s from indigenous peoples living remote areas. Although a statewide policy of screening all hospital patients and staff who have lived outside state for MRSA has prevented establishment multidrug-resistant epidemic MRSA, not SCCmec type IV V clones becoming established. Of 4,099 isolates analyzed (referred to Gram-positive Bacteria Typing Research Unit) July...
Background Bacterial pneumonia is a well described complication of influenza. In recent years, community-onset methicillin-resistant Staphylococcus aureus (cMRSA) infection has emerged as contributor to morbidity and mortality in patients with Since the emergence rapid dissemination pandemic A(H1N1)2009 influenzavirus April 2009, initial descriptions clinical features hospitalized have contained few details bacterial co-infection. Methodology/Principal Findings Patients community–acquired...
ABSTRACT Clonal complex 59 (CC59) community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) strains were characterized using pulsed-field gel electrophoresis, spa typing, multilocus sequence diagnostic DNA microarrays, and PCRs targeting staphylococcal cassette chromosome mec (SCC ) elements Panton-Valentine leukocidin (PVL). Six distinct groups within CC59 characterized. At least seven different variants of SCC identified (IVa [2B], IVb IVd IV variant IVa [2B&5], V...
Panton Valentine Leukocidin (PVL) has been associated with invasive Staphylococcus aureus soft tissue and pneumonic infections. From September 2007 to January 2009 at Royal Perth Hospital we tested for the PVL gene in S. isolates from an site, a suspected PVL-related infection all MRSA isolates. We could access medical records 141 positive (PVL + ve) infections compared these control group comprised of 148 negative (PVL-ve) In ve 62 were (48 ST93-MRSA-IV) 79 methicillin-sensitive aureus,...
Background. Antimicrobial resistance (AMR) by Neisseria gonorrhoeae is considered a serious global threat. Methods. In this nationwide study, we used MassARRAY iPLEX genotyping technology to examine the epidemiology of N. and associated AMR in Australian population. All available isolates (n = 2452) received from reference laboratories January June 2012 were included study. Genotypic data combined with phenotypic information define strain types. Results. A total 270 distinct types observed....
Community-onset infections caused by methicillin-resistant Staphylococcus aureus (COMRSA) are being increasingly reported worldwide.A retrospective study was performed of 14 patients with 15 episodes COMRSA bacteremia (COMRSAB) admitted to the Royal Darwin Hospital, Northern Territory, Australia from 1998 2001. Isolates COMRSAB underwent extended susceptibility testing and molecular typing pulsed field gel electrophoresis allotyping staphylococcal cassette chromosome mec (SCCmec) region...
The complexes [M(NO)(L)X(Y)][L = tris(3,5-dimethylpyrazolyl)borate; M Mo, X Cl, Y OPh; W, SPh; or NC4H4, OPh, SPh] have been prepared and characterised. electrochemical properties of these compounds were investigated by cyclic voltammetry compared with those others in the series [M(NO)(L)X(Y)](M Mo W; NHPh, SPh). It was found that thiophenolate reduced at slightly more anodic potentials than their phenolate analogues while arylamide significantly cathodic potentials. In general tungsten ca....
To describe the control of an outbreak infection and colonization with New York/Japan methicillin-resistant Staphylococcus aureus (MRSA) clone in multiple healthcare facilities, to demonstrate importance making MRSA management policy involving molecular typing into a statewide public health responsibility.A range including 2 metropolitan teaching hospitals regional hospital, as well several community long-term care facilities nonmetropolitan region.A comprehensive, epidemiological...
Background. It is uncertain whether particular clones causing invasive community-onset methicillin-resistant and methicillin-sensitive Staphylococcus aureus (cMRSA/cMSSA) infection differ in virulence. Methods. Invasive cMRSA cMSSA cases were prospectively identified. Principal component analysis was used to derive an illness severity score (ISS) from clinical data, including 30-day mortality, requirement for intensive hospital support, the presence of bloodstream infection, length stay. The...