A5029791959- Microfluidic and Bio-sensing Technologies
- Ultrasound and Hyperthermia Applications
- Ubiquitin and proteasome pathways
- Cellular transport and secretion
- Advanced biosensing and bioanalysis techniques
- Microbial Inactivation Methods
- Micro and Nano Robotics
- Advanced Biosensing Techniques and Applications
- Spaceflight effects on biology
- Protein Degradation and Inhibitors
- Single-cell and spatial transcriptomics
- Ultrasound Imaging and Elastography
- Molecular Biology Techniques and Applications
- Glycosylation and Glycoproteins Research
California Institute of Technology
2021-2024
The ability to physically manipulate specific cells is critical for the fields of biomedicine, synthetic biology, and living materials. Ultrasound has with high spatiotemporal precision via acoustic radiation force (ARF). However, because most have similar properties, this capability disconnected from cellular genetic programs. Here, we show that gas vesicles (GVs)-a unique class gas-filled protein nanostructures-can serve as genetically encodable actuators selective manipulation. Because...
Endocytosis and lysosomal trafficking of cell surface receptors can be triggered by interaction with endogenous ligands. Therapeutic approaches such as LYTAC
Cell-based therapies are a major emerging category of medicine. The ability engineered cells to traffic and function at specific anatomical locations is aspect their performance. However, there lack non-invasive, non-ionizing, cost-accessible methods track these inside the body ensure proper function. Here, we establish platform for in vivo imaging primary cell using ultrasound - ubiquitously accessible technology high-resolution non-invasive imaging. We introduce optimize lentiviral...