A5091769259- Anesthesia and Neurotoxicity Research
- Anesthesia and Sedative Agents
- Cardiac, Anesthesia and Surgical Outcomes
- Airway Management and Intubation Techniques
- Obstructive Sleep Apnea Research
- Skin and Cellular Biology Research
- Metabolism and Genetic Disorders
- Respiratory Support and Mechanisms
- COVID-19 and healthcare impacts
- Connective tissue disorders research
- Mitochondrial Function and Pathology
- Diet and metabolism studies
- Cellular transport and secretion
- Cardiac Arrest and Resuscitation
- Restraint-Related Deaths
- Infection Control and Ventilation
- Trauma Management and Diagnosis
- Coronary Artery Anomalies
- Ion Transport and Channel Regulation
- Muscle and Compartmental Disorders
- Thermal Regulation in Medicine
- Intraoperative Neuromonitoring and Anesthetic Effects
- Myasthenia Gravis and Thymoma
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Hereditary Neurological Disorders
The University of Texas Southwestern Medical Center
2020-2025
Medical City Children's Hospital
2023
University of Florida
2017-2021
Outcomes Research Consortium
2020-2021
Southwestern Medical Center
2020
Florida College
2017-2020
Children's Medical Center
2020
ABSTRACT Background In pediatric patients, the use of processed EEG monitoring may reduce amount anesthesia administered while maintaining adequate depth anesthesia. Aims The primary aim this study was to evaluate whether a BIS monitor guide sevoflurane administration might average end tidal concentration used in children 4–18 years age. Methods Participants three age groups (4–8, 9–12, and 13–18 years) were randomized either guided group or control group. Use as maintenance anesthetic only...
Coronavirus disease 2019 (COVID-19) is associated with high perioperative morbidity and mortality among adults. The incidence severity of anesthetic complications in children severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) unknown. We hypothesized that there would be an increased intra- postoperative SARS-CoV-2 infection as compared to those negative testing. conducted a retrospective cohort study analyzing for <18 years age who underwent anesthesia between April 28 September...
Sugammadex is a novel reversal agent for the neuromuscular blocking agents rocuronium and vecuronium; it has been shown to rapidly completely reverse blockade vecuronium, even when profound. We present case of 2-week-old, 850-g infant born at 25 weeks' gestation, who presented operating room exploratory laparotomy repair ileal atresia. Anesthesia was induced with 1.2 mg/kg administered. The neonate experienced rapid oxyhemoglobin desaturation progressively became very difficult mask...
Abstract Background Anesthetic regimens using dexmedetomidine and short‐acting opioids have been suggested as potential alternatives to sevoflurane‐based anesthesia in children. The primary aim of this study is compare demographics, intraoperative characteristics, complications general anesthetics which were used without sevoflurane, or combination with a low sevoflurane concentration, children 36 months old younger. secondary evaluate bispectral index (BIS) values when available these...
Abstract Stiff skin syndrome is a rare genetic disorder that present in infancy or early childhood. It characterized by hard, inflexible and limited joint mobility making anesthetic management of these patients challenging. Their neck flexibility chest wall rigidity make intubation mask ventilation difficult. Intraoperative positioning can be challenging due to contractures potential entrapment peripheral neuropathy. Even though intravenous access relatively easy, central venous cannulation...
Pediatric laryngotracheal injuries from blunt force trauma are rare but can lead to significant morbidity and mortality. In pediatric patients with severe disruption, extracorporeal membrane oxygenation has been used improve ventilation until definitive repair be performed. We describe the case of a 3-year-old girl neck secondary an all-terrain vehicle accident in which her was clotheslined against fence, leading complete tracheal transection at C7-T1 level. Emergent cannulation initiated....
Propionic acidemia is a rare genetic disorder of metabolism that predisposes patients to metabolic acidosis, lethargy, neurologic dysfunction, developmental delays, and cardiomyopathy. Perioperative anesthetic management guided toward mitigating the effects preoperative fasting times, maintaining normovolemia, preventing cardiovascular complications secondary underlying Commonly used agents may have undesirable side in these patients. Propofol, lactate Lactated Ringer's, neuromuscular...
Nociception is the detection of noxious stimulation by nervous system. The PMD-200 monitor a validated, emerging technology for intraoperative monitoring using nociception level (NOL) index. We describe pediatric case an open resection paraganglionic masses during which episodic increases in NOL index and blood pressure coincided with tumor manipulation, presumably due to catecholamine surge. Since patient was under stable adequate analgesia, likely reflected physiologic effects handling...
: A 4-month-old girl initially presented to the pediatric ICU at 9 days old with multiorgan failure and cerebellar hemorrhage secondary disseminated enteroviral infection was eventually listed for liver transplant. Due severe coagulopathy, she developed a hemothorax after line placement. Despite operative exploration multiple recombinant factor VIIa doses, massive bleeding continued. The finally controlled thromboelastography-targeted platelet cryoprecipitate transfusion in addition...
Children with mitochondrial disorders represent a subset of patients who require unique anesthetic considerations. Routinely administered medications for general anesthesia, such as propofol, have been shown to increase the risk developing metabolic acidosis. In addition, both depolarizing and nondepolarizing neuromuscular blockers are contraindicated due hyperkalemic cardiac arrest worsening preexisting muscle weakness, respectively. These limitations pose challenges while choosing...
Surgical correction for scoliosis is undertaken to avoid progression cardiopulmonary compromise as well improve the patient's overall quality of life. In this case report, we presented a 14-year-old girl with epidermolysis bullosa simplex and Gitelman's syndrome who underwent posterior spinal fusion scoliosis. The perioperative planning intraoperative management patient unique combination comorbidities undergoing complex, high-risk surgical procedure were not previously chronicled in...
A four-month-old female infant presented for a thoracoscopic aortopexy severe tracheomalacia. The case proceeded uneventfully until specimen bag was introduced into the chest to remove thymus. child developed significant ST segment elevations in all 12 leads on electrocardiogram. An emergent intraoperative echocardiogram performed but did not reveal any findings account diffuse elevations. remained elevated 48 hours following procedure with no apparent hemodynamic instability or structural...