A5016418317- Nerve Injury and Rehabilitation
- Muscle activation and electromyography studies
- Nerve injury and regeneration
- Peripheral Nerve Disorders
- Neuroscience and Neural Engineering
- Orthopedic Surgery and Rehabilitation
- Transcranial Magnetic Stimulation Studies
- Cerebral Palsy and Movement Disorders
- Motor Control and Adaptation
- Planarian Biology and Electrostimulation
- Spinal Cord Injury Research
- Electrospun Nanofibers in Biomedical Applications
- Neurogenetic and Muscular Disorders Research
- Shoulder Injury and Treatment
- Amyotrophic Lateral Sclerosis Research
- Reconstructive Surgery and Microvascular Techniques
- EEG and Brain-Computer Interfaces
- Wound Healing and Treatments
- Pain Management and Treatment
- Tissue Engineering and Regenerative Medicine
- Neurological disorders and treatments
- Advanced Sensor and Energy Harvesting Materials
- Pressure Ulcer Prevention and Management
- Pain Mechanisms and Treatments
- Signaling Pathways in Disease
University of Alberta
2016-2025
University of Toronto
2009-2022
Creative Commons
2018-2022
Mayo Clinic in Florida
2022
Klinikum Ludwigshafen
2022
Hospital for Sick Children
2018-2021
SickKids Foundation
2019-2021
Laboratoire de Génie Chimique
2020
Hôpital des Enfants
2020
University of Hong Kong
2020
Brief postsurgical electrical stimulation (ES) has been shown to enhance peripheral nerve regeneration in animal models following axotomy and crush injury. However, whether this treatment is beneficial humans with sensory injury not tested. The goal of study was test the hypothesis that ES would digital transection compared surgery alone.Patients complete underwent epineurial repair. After coaptation severed ends, fine wire electrodes were implanted before skin closure. Postoperatively,...
We present a case study of novel variation the targeted sensory reinnervation technique that provides additional control over restoration after transhumeral amputation. The use intraoperative somatosensory evoked potentials on individual fascicles median and ulnar nerves allowed us to specifically target reroute cutaneous at distance away from anticipated motor sites in amputee. This resulted restored hand maps nerve discrete spatially separated areas. In addition, subject was able native...
: To assess the validity and reliability of an office-based surrogate measure lumbar spine-stabilization endurance capability; to establish norms in asymptomatic group; compare their measures with those from a group chronic mechanical low-back pain patients.: Eight healthy subjects participated tool-validation portion study that consisted surface electromyographic (EMG) measurements core muscle activation during prone supine bridging. Subsequently, normative test-retest bridging duration...
Abstract BACKGROUND Patients with severe cubital tunnel syndrome often have poor functional recovery conventional surgical treatment. Postsurgical electrical stimulation (PES) has been shown to enhance axonal regeneration in animal and human studies. OBJECTIVE To determine if PES following surgery for would result better outcomes compared alone. METHODS this randomized, double-blind, placebo-controlled trial were randomized a 1:2 ratio the control or groups. Control patients received sham...
<h3>BACKGROUND:</h3> Unprecedented demand for N95 respirators during the coronavirus disease 2019 (COVID-19) pandemic has led to a global shortage of these masks. We validated rapidly applicable, low-cost decontamination protocol in compliance with regulatory standards enable safe reuse respirators. <h3>METHODS:</h3> inoculated 4 common models severe acute respiratory syndrome 2 (SARS-CoV-2) and evaluated viral inactivation after disinfection 60 minutes at 70°C 0% relative humidity....
Abstract Several studies have suggested that low‐level laser therapy (LLLT) is effective in patients with carpal tunnel syndrome (CTS). In a double‐blind randomized controlled trial of LLLT, 15 CTS patients, 34 to 67 years age, were randomly assigned either the control group ( n = 8) or treatment =7). Both groups treated three times per week for 5 weeks. Those received 860 nm galium/aluminum/arsenide at dosage 6 J/cm 2 over tunnel, whereas those sham laser. The primary outcome measure was...
The goal of this study was to test the feasibility and efficacy using microstimulators (BIONs) correct foot drop, first human application BIONs in functional electrical stimulation (FES). A prototype BIONic drop stimulator developed by modifying a WalkAide2 control BION ankle dorsiflexor muscles. compared with surface common peroneal nerve provided normal stimulator. Compared stimulation, we found that deep produces more balanced flexion movement without everting foot. three-dimensional...
Abstract The Moberg Pick‐Up Test is a standardized test for assessing hand dexterity. Although reduction of sensation in the occurs with aging, effect age on subject's performance has not been examined. primary goal this study was to examine impact aging and, secondarily, gender and handedness, 116 healthy subjects. average time complete each four subsets analyzed using Kruskal–Wallis, Mann–Whitney U , Wilcoxon signed‐rank tests. results show that dexterity subjects significantly affected by...
Abstract There is a paucity of validated tests to quantify hand function impairment due carpal tunnel syndrome (CTS). The aim this study was test the validity and reliability Purdue Pegboard Test (PPT) in CTS patients. We compared 190 patients with 122 healthy, age‐matched controls. severity determined based on electrophysiologic parameters Levine Self‐Assessment Questionnaire. time complete PPT test–retest were tested. high an intraclass correlation coefficient 0.91. Compared healthy...
In animals, the recovery of motoneuron excitability in months following a complete spinal cord injury is mediated, part, by increases constitutive serotonin (5-HT2) and norepinephrine (α1) receptor activity, which facilitates reactivation calcium-mediated persistent inward currents (CaPICs) without ligands below injury. this study we sought evidence for similar role monoamine activity development spasticity human chronically injured participants with partially preserved sensory motor...
Predicting the future has long been regarded as a powerful means to improvement and success. The ability make accurate timely predictions enhances our control situation environment. Assistive robotics is one prominent area in which foresight of this kind can bring improved quality life. In article, we present new approach acquiring maintaining predictive knowledge during online ongoing operation an assistive robot. learn accurate, temporally abstracted shown through two case studies: 1)...
Shoulder dysfunction is common after neck dissection for head and cancer (HNC). Brief electrical stimulation (BES) a novel technique that has been shown to enhance neuronal regeneration nerve injury by modulating the brain-derived neurotrophic growth factor (BDNF) pathways. The objective of this study was evaluate effect BES on postoperative shoulder function following oncologic dissection. Adult participants with new diagnosis HNC undergoing Level IIb +/- V were recruited. Those in...