A5049040242- Health Systems, Economic Evaluations, Quality of Life
- Breast Cancer Treatment Studies
- Substance Abuse Treatment and Outcomes
- Lipoproteins and Cardiovascular Health
- Pharmaceutical Economics and Policy
- Chronic Myeloid Leukemia Treatments
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Economic and Financial Impacts of Cancer
- Breast Implant and Reconstruction
- Global Cancer Incidence and Screening
- Lung Cancer Treatments and Mutations
- Alcohol Consumption and Health Effects
- Renal cell carcinoma treatment
- Sarcoma Diagnosis and Treatment
- Lymphoma Diagnosis and Treatment
- Healthcare Policy and Management
- Clinical practice guidelines implementation
- Ovarian cancer diagnosis and treatment
- Statistical Methods in Clinical Trials
- Sepsis Diagnosis and Treatment
- Liver Disease Diagnosis and Treatment
- Spondyloarthritis Studies and Treatments
- Radiomics and Machine Learning in Medical Imaging
- Hepatitis B Virus Studies
- BRCA gene mutations in cancer
University of Sheffield
2012-2022
New York University Press
2017
Cambridge University Press
2017
Royal Australasian College of Surgeons
2017
The University of Adelaide
2017
Clinical Orthopaedics and Related Research
2010
University Hospital of Wales
2010
Cardiff University
2010
Addenbrooke's Hospital
2010
Perth Royal Infirmary
2009
Aims: To estimate the cost-effectiveness and resourcing implications of universal alcohol screening brief intervention (SBI) programmes in primary care England. Methods: This was a health economic model, combining evidence effectiveness resource requirements SBI activities with existing epidemiological modelling relationship between consumption harms. Results: Screening patients on registration family doctor would steadily capture ∼40% population over 10-year programme; at next consultation...
This methodology paper sets out a mathematical description of the Sheffield Alcohol Policy Model version 2.0, model to evaluate public health strategies for alcohol harm reduction in UK. Policies that can be appraised include minimum price per unit alcohol, restrictions on discounting, and broader measures. The estimates impact consumers, services, crime, employers, retailers government tax revenues. synthesis commercial data sources inform structure is described. A detailed algebraic...
ABSTRACTObjective: Based on positive safety and efficacy data, a quadrivalent Human PapillomaVirus (HPV) vaccine has been approved in Switzerland to prevent HPV types 6, 11, 16 18 infections. The objective of this study was explore the cost-effectiveness an vaccination Switzerland.Design methods: A Markov model natural history infection adapted Swiss context followed hypothetical cohort 41 200 girls aged 11 years over their lifetime. Main epidemiological economic parameters were extracted...
Objectives. The primary aim of this study was to estimate annual health care costs for biologic-naïve patients with PsA in the UK. relationship between disease severity, defined by physical limitations, and also explored. Methods. This utilized data from British Society Rheumatology Biologics Register (BSRBR) develop a multivariate model estimating severity parameters available routine data. HAQ Disability Index used determine severity. algorithm then applied Health Improvement Network...
This paper sets out the development of a methodological framework for detailed evaluation public health strategies alcohol harm reduction to meet UK policy-makers needs. Alcohol is known cause substantial harms, and controlling its affordability availability are effective policy options. Analysis synthesis variety commercial data sources needed evaluate impact on consumers, services, crime, employers industry, so sound important. We discuss iterative process engage with stakeholders,...
Diabetes is associated with premature death and a number of serious complications. The presence comorbid depression makes these outcomes more likely results in increased healthcare costs. aim this work was to assess the health economic having both diabetes depression, cost-effectiveness potential policy changes improve care pathway: improved opportunistic screening for collaborative treatment, combination both.A mathematical model pathways experienced by people diagnosed type-2 England...
Background: While evidence shows high-dose statins reduce cardiovascular events compared with moderate doses in individuals acute coronary syndrome (ACS), many primary care trusts (PCT) advocate the use of generic simvastatin 40 mg/day for these patients. Methods and results: Data from 28 RCTs were synthesized using a mixed treatment comparison model. A Markov model was used to evaluate cost-effectiveness treatments taking into account adherence likely reduction cost atorvastatin when patent...
Aims To determine whether the provision of contingency management using financial incentives to improve hepatitis B vaccine completion in people who inject drugs entering community treatment represents a cost-effective use health-care resources. Design A probabilistic cost-effectiveness analysis was conducted, decision-tree estimate short-term clinical and cost impact vaccination strategies, followed by Markov process evaluate long-term consequences costs associated with infection. Settings...
Objective and Methods: A decision analytic model was built to assess the paediatric rotavirus gastroenteritis (RVGE) burden potential benefits associated with introduction of RotaTeq®† (pentavalent vaccine) in Belgium.Results: In absence a (RV) immunisation programme, RVGE estimated account for about 5,860 hospitalisations, 1,720 cases nosocomial infections, 9,410 treated by general practitioners/paediatricians (GP/P) 10,790 not seeking medical care birth cohort followed up 5 years age....