Anabella Handal‐Silva

ORCID: 0000-0002-6915-5655
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About
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Research Areas
  • Water Quality and Pollution Assessment
  • Alzheimer's disease research and treatments
  • Heavy Metal Exposure and Toxicity
  • Public Health and Environmental Issues
  • Pancreatic function and diabetes
  • Water Quality Monitoring and Analysis
  • Water Resource Management and Quality
  • Urinary Bladder and Prostate Research
  • Parkinson's Disease Mechanisms and Treatments
  • Ovarian function and disorders
  • Garlic and Onion Studies
  • Regulation of Appetite and Obesity
  • Cardiovascular, Neuropeptides, and Oxidative Stress Research
  • Tryptophan and brain disorders
  • Dye analysis and toxicity
  • Environmental and Social Impact Assessments
  • Vibrio bacteria research studies
  • Cancer therapeutics and mechanisms
  • Enzyme-mediated dye degradation
  • Hypothalamic control of reproductive hormones
  • Fecal contamination and water quality
  • Sulfur Compounds in Biology
  • Pharmacogenetics and Drug Metabolism
  • Urban Stormwater Management Solutions
  • Agricultural and Food Production Studies

Benemérita Universidad Autónoma de Puebla
2003-2024

Energy drinks (EDs) are often consumed in combination with alcohol because they reduce the depressant effects of alcohol. However, different researches suggest that chronic use these psychoactive substances can trigger an oxidative and inflammatory response. These processes regulated by both a reactive astrogliosis increase proinflammatory cytokines such as IL‐1 β , TNF‐ α iNOS, causing cell death (apoptosis) at central peripheral nervous systems. Currently, mechanisms toxicity caused mixing...

10.1155/2016/8725354 article EN cc-by Oxidative Medicine and Cellular Longevity 2016-01-01

The health risks of Emilio Portes Gil’s population, for the exposition to Atoyac River pollution in State Puebla, was evaluated. objective determine concentration nine heavy metals by ingesting water from wells and spri ngs. chronic daily intake (CDI), hazard quotient (HQ), index (HI), carcinogenic risk (CRI) adults, teenagers, children were estimated. results showed that Fe, Al, Ni, Pb some samples exceeded recommended standards human consumption significantly higher dry season. due...

10.3390/w11020277 article EN Water 2019-02-05

Abstract Metabolic syndrome (MS) is a health problem that characterized by body fat accumulation, hypertension, dyslipidemia, and hyperglycemia; recently, it has been demonstrated MS also damages memory processes. The first‐line drug in the treatment of type 2 diabetes mellitus metformin, which an antihyperglycemic agent. This shown to produce neuroprotection improve However, mechanism involved this unknown. A 90‐day administration metformin improved cognitive processes rats with as...

10.1002/syn.22153 article EN Synapse 2020-03-19

Population growth, poorly planned industrial development and uncontrolled production processes have left a significant footprint of environmental deterioration in the Alto Atoyac watershed. In this study, we propose using integrated pollution index (PI) to characterize temporary variations surface water quality during rapid urbanization process municipalities San Martín Texmelucán (SMT) Tepetitla de Lardizabal (TL), states Puebla Tlaxcala, between 1985 2020. We assessed correlation...

10.3390/su14020667 article EN Sustainability 2022-01-07

Cadmium (Cd) is a heavy metal classified as carcinogen whose exposure could affect the function of central nervous system. Studies suggest that Cd modifies neuronal morphology in hippocampus and affects cognitive tasks. The oxidative stress pathway proposed mechanism toxicity. However, this not precise yet. This study aimed to evaluate effect administration on markers male rat's hippocampus. Male Wistar rats were divided into (1) control (drinking water) (2) treatment with (32.5 ppm cadmium...

10.1002/syn.22242 article EN Synapse 2022-06-16

Abstract Neurological disorders (NDs) are diseases of the central and peripheral nervous systems that affect more than one billion people worldwide. The risk developing an ND increases with age due to vulnerability different organs genetic, environmental, social changes consequently cause motor cognitive deficits disable person from their daily activities individual productivity. Intrinsic factors (genetic factors, age, gender) extrinsic (addictions, infections, or lifestyle) favor...

10.1002/syn.22301 article EN Synapse 2024-05-31

The Atoyac River crosses the metropolitan area of Puebla-Tlaxcala in Mexico and presents a state pollution that has been scarcely studied. In 2016, water quality river was evaluated based on physicochemical bacteriological parameters, under guidelines established for Maximum Permissible Limit (MPL) Aquatic Life Protection (ALP) Agricultural Irrigation (AI). sampling sites were Covadonga Dam, Echeverría an irrigation canal. Water from wells spring Emilio Portes Gil (EPG) population uses...

10.3390/w10030267 article EN Water 2018-03-04

Abstract Urbanization, livestock activities, and rainfall are factors that contribute to the contamination of inland water. This study aimed determine spatial temporal variability total coliforms (TCs) fecal (FCs) in surface water San Pedro Lake as well gills skin Nile tilapia ( Oreochromis niloticus ) cultivated lake. The consisted seasonal sampling during an annual cycle. Using multiple‐tube fermentation technique, we quantified microbial load TCs lake fish. median TC FC groups showed...

10.1002/wer.1423 article EN Water Environment Research 2020-08-05

In this study, we evaluated the effects of intrabursal administration cabergoline and N-acetylcysteine on ovarian hyperstimulation syndrome (OHSS) in an immature rat model. The study assessed body, ovarian, uterine weights, as well concentrations vascular endothelial growth factor A (VEGF-A). Moreover, levels MDA, 4-HDA, nitrites were homogenates, permeability was quantified peritoneal cavity. Ovarian morphology characterized using histology hematoxylin-eosin staining, determining count...

10.1155/ije/1634072 article EN cc-by International Journal of Endocrinology 2024-01-01

We study the effects of an intratesticular injection (ITIn) infiltrating agent dimethyl sulfoxide (DMSO) on seminiferous tubule structure in adult rats. Experimental groups 32 rats received a ITIn with 50µL pure DMSO inside each testicle; sham group were formed subjected to surgical technique but not ITIn; test effectiveness like agent, other 50µg haloperidol (dopaminergic antagonist) dissolved DMSO. All sacrificed at 4-, 8-, 12- or 16-day post ITIn. Compared groups, doesn’t alter epithelium...

10.35429/jsl.2024.11.30.1.21 article EN Revista de Simulación y Laboratorio 2024-12-30

The largest economic, population, administrative, and service production of the State Puebla (east-central Mexico) is concentrated in Metropolitan Area (MAP), its effect on water quality Atoyac River substantial. anthropogenic contamination tributaries MAP was evaluated characterized. For this purpose, industry types industrial density (ID) were identified, physical–chemical urban Atoyac, Rabanillo, Zapatero Rivers, Covadonga Echeverría Dams analyzed. In addition, cytotoxicity using biomodel...

10.3390/su151310565 article EN Sustainability 2023-07-05

Sambucus canadensis is used in traditional medicine mainly indigenous communities as an anti-inflammatory, antiviral, to treat cough, fever and other ailments, however, its use must be validated on scientific bases. The aim of this study was evaluate the genotoxic cytotoxic effect ethanol extract meristem cells Allium sativum with 5 treatments at concentrations 125, 250, 500, 1000 1500 mg/L. Two thousand were counted per treatment; mitotic index (MI) nuclear abnormalities (NA) evaluated....

10.36253/caryologia-1307 article EN cc-by Caryologia 2022-07-07

The Atoyac River crosses the metropolitan area of Puebla, Mexico, and presents a condition severe degradation that has been poorly studied. research was conducted in year 2016 analyzed space-time dynamics water quality river, increase pollution period 2011–2016, used for agricultural irrigation human consumption population Emilio Portes Gil, Ocoyucan, based on official Mexican standards (NOMs). anoxic state river demonstrated (~1.47 mgO2/L) high organic pollution, particularly...

10.20944/preprints201711.0185.v1 preprint EN 2017-11-29

We evaluated the function of dopaminergic receptors (DAR) anterior hypothalamus (AH) on estral cycle (EC) regulation and spontaneous ovulation by a single microinjection (MI) with antagonist haloperidol (HLP) in adult rats. One hundred thirty nine rats that exhibit forth-day cycles (cyclic animals: CA) received stereotaxic surgery (STXS) right, left or both AH sides were distributed three different groups MI 1 µL of: HLP (15 µg) dimethyl-sulfoxide (vehicle) other false group. All animals...

10.35429/ejrg.2019.8.5.27.50 article EN ECORFAN Journal Republic of Guatemala 2019-06-30

UGT1A6 catalyzes the glucuronidation of several xenobiotics and drugs widely used. Changes in rate are attributed to inter-personal inter-ethnic variations, that can impact expression or enzyme function. Frequencies genetic polymorphisms have been reported another countries; however, there no date frequencies Mexican population. The aim this work was determine genotypic allelic 19T˃G a mestizo population state Puebla compare them with observed other populations. Peripheral blood DNA obtained...

10.35429/ejrg.2019.9.5.13.20 article EN ECORFAN Journal Republic of Guatemala 2019-12-31

La determinación de cambios en la cubierta terrestre (CT) es importante para entender dinámica los ecosistemas. En este estudio se analizaron espaciales y temporales el municipio Ixtacamaxtitlán, Puebla durante periodo 2000-2015, utilizando mapas globales Agencia Espacial Europea ESA-CCI-LC. Para ello, determinó matriz cambios, tasa anual cambio probabilidad permanencia, así como precisión del mapa CT 2015. Los resultados indican que las pérdidas concentraron coberturas arboladas pastizales...

10.21829/myb.2021.2732210 article ES Madera y Bosques 2021-12-30
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