A5039213588- Prostate Cancer Diagnosis and Treatment
- SARS-CoV-2 and COVID-19 Research
- Prostate Cancer Treatment and Research
- Blood Pressure and Hypertension Studies
- Adipokines, Inflammation, and Metabolic Diseases
- COVID-19 Clinical Research Studies
- Angiogenesis and VEGF in Cancer
- Biliary and Gastrointestinal Fistulas
- Cancer, Lipids, and Metabolism
- Cardiovascular Disease and Adiposity
- Inflammatory Biomarkers in Disease Prognosis
- Sexual Differentiation and Disorders
- COVID-19 epidemiological studies
- Artificial Intelligence in Healthcare
- Extracellular vesicles in disease
- Lipoproteins and Cardiovascular Health
- Oral Health Pathology and Treatment
- Biomarkers in Disease Mechanisms
- Pneumothorax, Barotrauma, Emphysema
- Pediatric Hepatobiliary Diseases and Treatments
- Biosensors and Analytical Detection
- Neurological diseases and metabolism
- Essential Oils and Antimicrobial Activity
- Endoplasmic Reticulum Stress and Disease
- Omental and Epiploic Conditions
Ganesh Shankar Vidyarthi Memorial Medical College
2013-2023
All India Institute of Medical Sciences
2022
London North West Healthcare NHS Trust
2020
King George's Medical University
2009
Concurrent with the misbalance of oxidizing agents and antioxidants, high blood pressure is a major physical burden condition in current scenario. Tumor necrosis factor-α (TNF-α) plays vital role pathogenesis hypertension. factor-α, inhibitor improves clinical symptoms however their outcome on has not been investigated. We investigated inflammatory marker TNF-α, malondialdehyde (MDA) ferric reducing antioxidant power (FRAP) hypertensive patients. measured randomly using an ambulatory observe...
A 60-year-old man presented with sudden onset right-sided chest pain and gradually worsening shortness of breath on exertion. Eleven days earlier, he had an admission COVID-19 pneumonitis requiring 8 continuous positive airway pressure. He was tachypnoeic a respiratory rate 24 breaths/min, oxygen saturations room air 91%. Examination revealed reduced entry resonant percussion note over the right hemithorax. Chest radiograph suggested complex pneumothorax; however, CT notable for widespread...
Testosterone, a primary androgen in males, is converted into its most active form, dihydrotestosterone (DHT), by 5α-reductase type 2 (encoded the SRD5A2 gene) prostate. DHT necessary for prostatic growth and has five times higher binding affinity than testosterone receptors. We hypothesized that polymorphic variations gene may affect risk of benign hyperplasia prostate cancer.We analyzed polymorphisms 217 BPH patients, 192 PCa cases, 171 controls. Genotyping was undertaken using direct DNA...
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), a new enveloped RNA virus known as (COVID-19) are most prevalent in humans and wild animals. All four species that is alpha, beta, delta theta have been identified till date responsible for human disease; causing influenza like illness (ILI). This has similar lineage of Middle East coronavirus (MERS-CoV) related (SARS-CoV). outbreak initially presented pneumonia-like group people Wuhan, China. The infection was said to be caused...
Prostate carcinoma is still a dreaded disease wanting more effective treatment and definitive early detection for better prognosis cure of life. The present study was planned to investigate the correlation vascular endothelial growth factor (VEGF) expression level microvessel density (MVD) between BPH prostate cancer subjects analyze their diagnostic prognostic value. Freshly diagnosed histopathologically confirmed 50 cases were included. Expression VEGF measured using Immunohistochemistry...
Formation of new blood vessels is necessary for the development and spread neoplasms more than 1 mm3 in volume, angiogenesis being responsible formation from pre-existing vessels. Vascular endothelial growth factor (VEGF) pivotal best studied angiogenic all human cancers. Therefore we designed this study to investigate role VEGF-A VEGF-C prostate cancer comparison with BPH controls a north Indian population.In case-control total 100 subjects were included on basis confirmed histopathological...
<span class="Bold">Purpose:</span><span> Angiogenesis is a necessary step in tumor growth and metastasis. Vascular endothelial factor (VEGF-c) major mediator of breast cancer angiogenesis. Therefore, we investigated the association polymorphism VEGF-c gene with risk prognostic characteristics tumors case-control study. </span><span class="Bold">Experimental Design: </span><span>We examined one (+936C/T) 75 cases control from Kanpur, Uttar Pradesh,...
Abstract BackgroundRecent evidences suggested that deficiency of Vit-D is associated with risk ischemic stroke and its severity. The mechanism behind relationship have been linked to total oxidant level some other modifiable factor like hypertension, diabetes, smoking alcohol consumption tobacco chewing. However, there are disappearances in evidences. aim this study find out the role Total oxidants disease progression.MethodsIn case control 205 individuals enrolled demographic data age,...
Background: Nowadays, the role of inflammation in malignancies is well understood, and it has been characterised at several phases tumourigenesis (initiation, promotion, invasion metastasis). Different studies suggested that neutrophils/lymphocyte ratio (NLR) linked with breast cancer (BC) survival prognosis. Aim: In present study, our aim was to study blood parameters (neutrophils, lymphocytes, NLR, lymphocyte-to-monocyte [LMR] neutrophil-to-monocyte [NMR]) BC. We examined correlation...
Aims: This study was done to find out retrospective case-control with respect myocardial infarction diagnosis on the basis of biochemical markers and lipid profile characteristics.
 Design Setting: conducted at Department Biochemistry sample collection LPS Institute Cardiology & Cardiac Surgery Department, Kanpur.
 Methods: The total number subjects participated in this (n=178), either sex (with age>65years) were included from case collected Outpatient (OPD) Indoor Patient...