A5008993849- Neural dynamics and brain function
- Neural Networks and Applications
- Advanced Memory and Neural Computing
- Memory and Neural Mechanisms
- Scientific Computing and Data Management
- Neural Networks and Reservoir Computing
- Functional Brain Connectivity Studies
- Neural and Behavioral Psychology Studies
- Visual perception and processing mechanisms
- Neuroscience and Neuropharmacology Research
- Cell Image Analysis Techniques
- Neurological disorders and treatments
- Cognitive Science and Mapping
- Neuroscience and Neural Engineering
- Computational Physics and Python Applications
- Teacher Education and Leadership Studies
- EEG and Brain-Computer Interfaces
- Education and Technology Integration
- Computer Graphics and Visualization Techniques
- Multimedia Communication and Technology
- Teacher Professional Development and Motivation
- Modular Robots and Swarm Intelligence
- Data Visualization and Analytics
- Research Data Management Practices
- Visual Attention and Saliency Detection
Laboratoire Bordelais de Recherche en Informatique
2015-2024
Institut Polytechnique de Bordeaux
2015-2024
Université de Bordeaux
2015-2024
Institut des Maladies Neurodégénératives
2014-2024
Centre National de la Recherche Scientifique
2015-2024
Institut national de recherche en informatique et en automatique
2015-2024
Centre de Recherche Inria Bordeaux - Sud-Ouest
2015-2024
Hôpital Cardiologique du Haut-Lévêque
2023
Synergy University
2013-2022
Centre National pour la Recherche Scientifique et Technique (CNRST)
2018-2019
Human cognitive control is uniquely flexible and has been shown to depend on prefrontal cortex (PFC). But exactly how the biological mechanisms of PFC support remains a profound mystery. Existing theoretical models have posited powerful task-specific representations, but not these develop. We show this can occur when set PFC-specific neural interact with breadth experience self organize abstract rule-like representations that generalization in novel tasks. The same model apply benchmark...
Computer science offers a large set of tools for prototyping, writing, running, testing, validating, sharing and reproducing results; however, computational lags behind. In the best case, authors may provide their source code as compressed archive they feel confident research is reproducible. But this not exactly true. James Buckheit David Donoho proposed more than two decades ago that an article about results advertising, scholarship. The actual scholarship full software environment, code,...
There is an apparent contradiction between experimental data showing that the basal ganglia are involved in goal-oriented and routine behaviors clinical observations. Lesion or disruption by deep brain stimulation of globus pallidus interna has been used for various therapeutic purposes ranging from improvement dystonia to treatment Tourette's syndrome. None these approaches reported any severe impairment automatic movement.To solve this conundrum, we trained 2 monkeys perform a variant...
Scientific code is different from production software. code, by producing results that are then analyzed and interpreted, participates in the elaboration of scientific conclusions. This imposes specific constraints on often overlooked practice. We articulate, with a small example, five characteristics computational science should possess: re-runnable, repeatable, reproducible, reusable, replicable. The be executable (re-runnable) produce same result more than once (repeatable); it allow an...
Machine learning–based approach unravels distinct pathological signatures induced by patient-derived α-synuclein seeds in monkeys.
Abstract We propose a model that includes interactions between the cortex, basal ganglia (BG), and thalamus based on dual competition. hypothesize striatum, subthalamic nucleus (STN), internal globus pallidus (GPi), thalamus, cortex are involved in closed feedback loops through hyperdirect direct pathways. These support competition process results ability of BG to make cognitive decision followed by motor one. Considering lateral cortical interactions, another takes place inside allowing...
GENERAL COMMENTARY article Front. Comput. Neurosci., 05 March 2015 https://doi.org/10.3389/fncom.2015.00030
The work studies the spatiotemporal activity propagation in a two-dimensional spatial system involving finite transmission speed. We derive numerical scheme detail to integrate corresponding evolution equation and validate derived algorithm by study of spatially periodic system. Finally, demonstrates numerically delay-induced breathers subjected anisotropic external input.
Abstract The prefrontal cortex is widely believed to play an important role in facilitating people's ability switch performance between different tasks. We present a biologically‐based computational model of (PFC) that explains its task switching terms the greater flexibility conferred by activation‐based working memory representations PFC, as compared with more slowly adapting weight‐based mechanisms. Specifically we show PFC can be rapidly updated when switches via dynamic gating mechanism...
Software is a fundamental pillar of modern scientiic research, not only in computer science, but actually across all elds and disciplines. However, there lack adequate means to cite reference software, for many reasons. An obvious rst reason software authorship, which can range from single developer whole team, even vary time. The panorama more complex than that, because roles be involved development: architect, coder, debugger, tester, team manager, so on. Arguably, the researchers who have...
Neurostimulation of the hippocampal formation has shown promising results for modulating memory but underlying mechanisms remain unclear. In particular, effects on theta-nested gamma oscillations and theta phase reset, which are both crucial processes, unknown. Moreover, these cannot be investigated using current computational models, consider with a fixed amplitude velocity. Here, we developed novel model that includes medial septum, represented as set abstract Kuramoto oscillators...
We investigate the formation and maintenance of ordered topographic maps in primary somatosensory cortex as well reorganization representations after sensory deprivation or cortical lesion. consider both critical period (postnatal) where are shaped post-critical maintained possibly reorganized. hypothesize that feed-forward thalamocortical connections an adequate site plasticity while cortico-cortical believed to drive a competitive mechanism is for learning. model small skin patch located...
In a previous work, we introduced computational model of area 3b which is built upon the neural field theory and receives input from simplified index distal finger pad populated by random set touch receptors (Merkell cells). This has been shown to be able self-organize following stimulation cope, some extent, with cortical or skin lesions. The main hypothesis that learning representations occurs at thalamo-cortical level while cortico-cortical connections serve stereotyped competition...
In humans, the attitude toward risk is not neutral and dissimilar between bets involving gains losses. The existence prevalence of these decision features in non-human primates are unclear. addition, only a few studies have tried to simulate evolution agents based on their risk. Therefore, we still ignore what extent Prospect theory’s claims evolutionarily rooted. To shed light this issue, collected data from nine macaques that performed or We confirmed overall behaviour coherent with...
DANA is a python framework (http://dana.loria.fr) whose computational paradigm grounded on the notion of unit that essentially set time dependent values varying under influence other units via adaptive weighted connections. The evolution unit's value are defined by differential equations expressed in standard mathematical notation which greatly ease their definition. organized into groups form model. Each can be connected to any (including itself) using connection. offers core objects needed...
We introduce a graphical method originating from the computer graphics domain that is used for arbitrary placement of cells over two-dimensional manifold. Using bitmap image whose luminance provides cell density, this guarantees discrete distribution positions respecting local density. This scales to any number cells, allows one specify enclosing shapes and scalable versatile alternative more classical assumption uniform spatial distribution. The illustrated on homogeneous neural field,...