A5062413539- Nanoplatforms for cancer theranostics
- Luminescence Properties of Advanced Materials
- Photodynamic Therapy Research Studies
- Adsorption and biosorption for pollutant removal
- Luminescence and Fluorescent Materials
- Advanced Nanomaterials in Catalysis
- Nanocluster Synthesis and Applications
- Advanced Photocatalysis Techniques
- Radiation Detection and Scintillator Technologies
- Carbon and Quantum Dots Applications
- Nanoparticle-Based Drug Delivery
- Nanomaterials for catalytic reactions
- Perovskite Materials and Applications
- Gas Sensing Nanomaterials and Sensors
- Molecular Sensors and Ion Detection
- Advanced biosensing and bioanalysis techniques
- Quantum Dots Synthesis And Properties
- Electrochemical sensors and biosensors
- Porphyrin and Phthalocyanine Chemistry
- Photoacoustic and Ultrasonic Imaging
- Biomedical Research and Pathophysiology
- Inorganic Fluorides and Related Compounds
- Gold and Silver Nanoparticles Synthesis and Applications
- Graphene and Nanomaterials Applications
- Analytical chemistry methods development
The University of Texas at Arlington
2015-2024
Zigong First People's Hospital
2024
Sichuan Agricultural University
2019-2024
University of Science and Technology Liaoning
2019-2024
Zhejiang Sci-Tech University
2023-2024
Xi’an Jiaotong-Liverpool University
2024
Army Medical University
2020-2024
Southwest Hospital
2020-2024
Nanjing Agricultural University
2023-2024
Institute of Urban Environment
2023
Photodynamic therapy (PDT) is an emerging effective treatment for cancer. However, the great promise of PDT bladder cancer has not yet been realized because tumor hypoxia. To address this challenge, we fabricated O2-generating HSA-MnO2-Ce6 NPs (HSA human serum albumin, Ce6 chlorin e6, and nanoparticles) to overcome hypoxia thus enhance photodynamic effect therapy. Methods: The were prepared. We investigated O2 generation in vitro vivo. orthotopic model C57BL/6 mice was established vivo...
Iodine ion is one of the most indispensable anions in living organisms, particularly being an important substance for synthesis thyroid hormones. Curcumin a yellow-orange polyphenol compound derived from rhizome
Endophthalmitis, derived from the infections of pathogens, is a common complication during use ophthalmology-related biomaterials and after ophthalmic surgery. Herein, aiming at efficient photodynamic therapy (PDT) bacterial biofilm eradication endophthalmitis, pH-responsive zeolitic imidazolate framework-8-polyacrylic acid (ZIF-8-PAA) material constructed for infection-targeted delivery ammonium methylbenzene blue (MB), broad-spectrum photosensitizer antibacterial agent. Polyacrylic (PAA)...
Abstract This is the first report of full‐color afterglow composites composed four multicolored (blue, green, orange, and red) carbon dots (CDs) in polyacrylamide (PAM) matrix. Thus, adjustable four‐color room‐temperature phosphorescence (RTP) CDs@PAM are prepared on a PAM platform. The abundant amide groups connected to functional CDs by hydrogen bonds, which promote intersystem crossover inhibit non‐radiative relaxation triple states (T 1 ) effectively shield quenching agents such as...
The explore of efficient strategies for nitrogen photofixation driven by visible light at room temperature and atmospheric pressure is still highly desirable until now but remains a great challenge. In...
None of the current biodegradable polymers can function as both implant materials and fluorescent imaging probes. The objective this study was to develop aliphatic photoluminescent (BPLPs) their associated cross-linked variants (CBPLPs) for biomedical applications. BPLPs are degradable oligomers synthesized from biocompatible monomers including citric acid, diols, various amino acids via a convenient cost-effective polycondensation reaction. be further into elastomeric polymers, CBPLPs. We...
In this letter, we report the synthesis of LaF3:Tb3+–meso-tetra(4-carboxyphenyl) porphine (MTCP) nanoparticle conjugates and investigate energy transfer as well singlet oxygen generation following x-ray irradiation. Our observations indicate that LaF3:Tb3+-MTCP are efficient photodynamic agents can be initiated by x-rays at a reasonably low dose. The addition folic acid to facilitate targeting folate receptors on tumor cells has no effect quantum yield production in nanoparticle-MTCP...
In this study, Ce(3+)-doped lanthanum(III) fluoride (LaF3:Ce(3+)) nanoparticles were synthesized by a wet-chemistry method in dimethyl sulfoxide (DMSO) and their application as an intracellular light source for photodynamic activation was demonstrated.The LaF3:Ce(3+)/DMSO have strong green emission with peak at approximately 520 nm, which is effectively overlapped the absorption of protoporphyrin IX (PPIX). The encapsulated into poly(D,L-lactide-co-glycolide (PLGA) microspheres along PPIX....
Photodynamic therapy (PDT), a treatment that uses photosensitizer, molecular oxygen, and light to kill target cells, is promising cancer method. However, limitation of PDT its dependence on not highly penetrating, precluding the tumors located deep in body. Copper-cysteamine nanoparticles are new type photosensitizer can generate cytotoxic singlet oxygen molecules upon activation by X-rays. In this paper, we report use copper-cysteamine nanoparticles, designed be targeted tumors, for...
Human norovirus is a leading cause of acute gastroenteritis worldwide in plethora residential and commercial settings, including restaurants, schools, hospitals. Methods for easily detecting the virus treating preventing infection are critical to stopping outbreaks, inactivation via nanoparticles (NPs) more universal attractive alternative other physical chemical approaches. Using GI.1 (Norwalk) virus-like particles (VLPs) as model viral system, this study characterized antiviral activity...
Adsorption of organic contaminants on carbon nanotubes (CNTs) is a critical behavior in the environmental application CNTs as sorbents and risk assessment both CNTs. Oxidation may introduce oxygen-containing groups CNTs' surface then alter adsorption contaminants. In this study, polar nonpolar compounds four multiwalled (MWCNTs) containing varied amounts were investigated to examine influence oxidation adsorption. We observed that MWCNTs reduced area-normalized capacity significantly because...
Copper and cobalt co-doped ZnS (ZnS:Cu,Co) afterglow nanoparticles were conjugated to photosensitizer tetrabromorhodamine-123 (TBrRh123) efficient energy transfer from the TBrRh123 was observed. In addition their X-ray excited luminescence, ZnS:Cu,Co also show long lasting afterglow, which continuously serve as a light source for photodynamic therapy (PDT) activation. Compared or alone, ZnS:Cu,Co-TBrRh123 conjugates low dark toxicity but high induced human prostate cancer cells. The results...
Aggregation-induced emission luminogens (AIEgens) exhibit efficient cytotoxic reactive oxygen species (ROS) generation capability and unique light-up features in the aggregated state, which have been well explored image-guided photodynamic therapy (PDT). However, limited penetration depth of light tissue severely hinders AIEgens as a candidate for primary or adjunctive clinical applications. Coincidentally, microwaves (MWs) show distinct advantage deeper tissues than light. Herein, first...
Herein, for the first time, we report copper-cysteamine (Cu-Cy) nanoparticles having Cu1+ instead of Cu2+ as an efficient heterogeneous Fenton-like catalyst highly selective cancer treatment. Initial measurements Cu-Cy's hydroxyl radical generation ability show that it behaves a reagent in presence H2O2 (100 μM) at pH 7.4, and its activity is dramatically enhanced under acidic conditions (pH 6.5 5.5). Notably, Cu-Cy exhibits high stability minimal copper release during reaction,...
A facile synthesis method of copper–cysteamine nanoparticles is reported and their application for cancer treatment through ROS-mediated mechanisms explored.