A5017768560- Glioma Diagnosis and Treatment
- Meningioma and schwannoma management
- Cancer Cells and Metastasis
- 3D Printing in Biomedical Research
- Pituitary Gland Disorders and Treatments
- Head and Neck Surgical Oncology
- MRI in cancer diagnosis
- Thermal Regulation in Medicine
- Fetal and Pediatric Neurological Disorders
- Autophagy in Disease and Therapy
- Immune cells in cancer
- Cell Adhesion Molecules Research
- Cancer-related molecular mechanisms research
- Macrophage Migration Inhibitory Factor
- Intracerebral and Subarachnoid Hemorrhage Research
- Cerebrospinal fluid and hydrocephalus
- Thermoregulation and physiological responses
- Chemokine receptors and signaling
- Histone Deacetylase Inhibitors Research
- Bone Tumor Diagnosis and Treatments
- Cerebral Venous Sinus Thrombosis
- Barrier Structure and Function Studies
- Innovative Microfluidic and Catalytic Techniques Innovation
- Cancer, Stress, Anesthesia, and Immune Response
- Adipose Tissue and Metabolism
Capital Medical University
2017-2021
Beijing Institute of Neurosurgery
2018-2021
Beijing Tian Tan Hospital
2017-2018
Chinese PLA General Hospital
2015
The Military General Hospital of Beijing PLA
2015
Chinese People's Armed Police General Hospital
2012-2014
Chinese People's Armed Police Force
2012-2014
Summary Aims To investigate the roles of Claudin‐5 ( CLDN 5) in regulating permeability blood‐brain barrier BBB ) during lung cancer brain metastasis. Results By silencing and overexpressing 5 gene human vascular endothelial hCMEC /D3) cells, we demonstrated attenuation cell migration ability 5's significant positive role proliferation 5‐overexpressing /D3 cells observed opposite result knockdown group. The reinforced expression reduced paracellular decreased invasion adenocarcinoma A549...
To predict cavernous sinus (CS) invasion by pituitary adenomas (PAs) pre-operatively using a radiomics method based on contrast-enhanced T1 (CE-T1) and T2-weighted magnetic resonance (MR) imaging.A total of 194 patients with Knosp grade two three PAs (training set: n = 97; test 97) were enrolled in this retrospective study. From CE-T1 T2 MR images, 2553 quantitative imaging features extracted. select the most informative features, least absolute shrinkage selection operator (LASSO) was...
Decision-making concerning the treatment of choroid plexus tumor (CPT) in pediatric patients remains a topic considerable debate. The aim this work was to describe clinical features and prognostic risk factors CPT population provide theoretical opinions regarding decisions for CPT.The data 96 with younger than 14 years were retrospectively analyzed. Clinical characteristics such as pathological type CPTs, rate severity hydrocephalus, outcome, recurrence investigated. For categorical...
Growth-hormone-secreting pituitary adenoma (GHSPA) is a benign tumour with high incidence and large economic burden, which greatly affects quality of life. The aetiological factors are yet to be clarified for GHSPA. Conventional two-dimensional (2D) monolayer culture cells cannot ideally reflect the growth status tumours in physiological environment, insufficiencies vitro models have severely restricted progress cancer research. Three-dimensional (3D) bioprinting technology being...
Pituitary adenomas, the most common type of lesion in sellar region, rank third among all brain tumors, with an incidence 73‑94 cases per 100,000 individuals. Due to its high resolution, MRI is highly efficient imaging and has emerged as appropriate method for tumor consistency evaluation. The present study aimed assess levels collagen types I III pituitary adenomas different consistencies determine value T2‑weighted (T2WI) predicting consistency. A total 55 patients were divided into soft...
Objective To study the characteristics and growth patterns of skull base meningioma communicating orbit cranial cavity via superior orbital fissure,and to discuss surgical methods intraoperative management.Methods A retrospective review clinical data 60 patients underwent microsurgical treatment through orbito -peronal approach for cranio -orbital meningiomas in our department between Jan 2007 2010 was performed specificity this kind tumors key - points operation method.Results Total tumor...
Background: Immunotherapy is a promising therapeutic approach for cancers. However, the immune background and interactions between pituitary adenomas (PAs) host system remain unclear. Methods: Poly-A enriched RNA sequencing was performed on 115 snap frozen PA samples. Estimating Proportion of Immune Cancer cells (EPIC) used to detect all main cell types (B cells, CD8+ T CD4+ macrophages NK cells) in tumor sample from expression genes. Immunohistochemical (IHC) staining validate findings....