Alexander D. Williams

ORCID: 0000-0002-7006-8364
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About
Contact & Profiles
Research Areas
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Antibiotic Resistance in Bacteria
  • Bacteriophages and microbial interactions
  • Antibiotic Use and Resistance
  • Pesticide and Herbicide Environmental Studies
  • Wastewater Treatment and Nitrogen Removal
  • Phosphorus and nutrient management
  • Bacterial Identification and Susceptibility Testing
  • SARS-CoV-2 detection and testing
  • Spectroscopy Techniques in Biomedical and Chemical Research
  • Agriculture, Soil, Plant Science
  • Microbial infections and disease research
  • Polar Research and Ecology
  • Water Treatment and Disinfection
  • Methane Hydrates and Related Phenomena
  • Geology and Paleoclimatology Research

University of Hong Kong
2023-2025

Hong Kong Science and Technology Parks Corporation
2023-2025

Laboratory of Data Discovery for Health
2023-2024

Loughborough University
2022

University of Nottingham
2021-2022

Waste from dairy production is one of the largest sources contamination antimicrobial resistant bacteria (ARB) and genes (ARGs) in many parts world. However, studies to date do not provide necessary evidence inform resistance (AMR) countermeasures. We undertook a detailed, interdisciplinary, longitudinal analysis slurry waste. The contained population ARB ARGs, with resistances current, historical never-used on-farm antibiotics; were associated Gram-negative Gram-positive mobile elements...

10.1016/j.envint.2022.107516 article EN cc-by Environment International 2022-09-13

ABSTRACT Interactions between humans, animals, and the environment are considered critical foci for addressing antimicrobial resistance (AMR). However, One Health data on AMR in low- middle-income countries presently scarce. Using metagenomics, we investigated whether how fecal antibiotic resistomes of humans influenced by exposure to intensive non-intensively reared poultry within contrasting settings urban wet markets ( n = 13) rural households 7) Bangladesh. We also 10) wastewater these...

10.1128/spectrum.01763-23 article EN cc-by Microbiology Spectrum 2023-11-16

Antimicrobial resistance (AMR) poses a significant threat to global health and sustainable development goals, especially in low- middle-income countries (LMICs). This study aimed understand the transmission of AMR between poultry, humans, environment Bangladesh using One Health approach. We analyzed whole genome sequences (WGS) 117 extended-spectrum β-lactamase-producing

10.1128/spectrum.03956-23 article EN cc-by Microbiology Spectrum 2024-05-03

Abstract Waste from dairy production is one of the world’s largest sources contamination antimicrobial resistant bacteria (ARB) and genes (ARGs). However, studies to date do not provide necessary evidence inform resistance (AMR) countermeasures. We undertook a detailed, interdisciplinary, longitudinal analysis slurry waste. The contained population ARB ARGs, with resistances current, historical never-used on-farm antibiotics; were associated Gram-negative Gram-positive mobile elements (IS...

10.1101/2022.02.22.481441 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2022-02-22

Abstract Many antibiotic resistance genes co-occur with for transition metals, such as copper, zinc, or mercury. In some environments, a positive correlation between high metal concentration and abundance of has been observed, suggesting co-selection due to presence. Of particular concern is the use copper zinc in animal husbandry, leading potential gut microbiomes, slurry, manure, amended soils. For antibiotics, predicted no effect concentrations have derived from laboratory measured...

10.1101/2020.09.14.295766 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2020-09-14

Waste from dairy production is one of the world’s largest sources contamination antimicrobial resistant bacteria (ARB) and genes (ARGs). However, studies to date do not provide necessary evidence inform resistance (AMR) countermeasures. We undertook a detailed, interdisciplinary, longitudinal analysis slurry waste. The contained population ARB ARGs, with resistances current, historical never-used on-farm antibiotics; were associated Gram-negative Gram-positive mobile elements (IS Ecp1 , Tn...

10.2139/ssrn.4079732 article EN SSRN Electronic Journal 2022-01-01
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