A5033064853- Child Nutrition and Water Access
- Child Nutrition and Feeding Issues
- Food Security and Health in Diverse Populations
- Poverty, Education, and Child Welfare
- Global Maternal and Child Health
- COVID-19 Impact on Reproduction
- Cerebral Palsy and Movement Disorders
- Viral gastroenteritis research and epidemiology
- Electrolyte and hormonal disorders
- Zoonotic diseases and public health
- Education and Critical Thinking Development
- Obesity and Health Practices
- Animal Ecology and Behavior Studies
- Obesity, Physical Activity, Diet
- Yersinia bacterium, plague, ectoparasites research
- Teaching and Learning Programming
- Educational Games and Gamification
- ICT Impact and Policies
- Nutritional Studies and Diet
Alliance for International Medical Action
2016-2024
Médecins Sans Frontières
2012
Severe acute malnutrition (SAM) is currently defined by the WHO as either a low mid-upper arm circumference (i.e. MUAC <115 mm), weight-for-height z-score WHZ <− 3), or bilateral pitting oedema. and do not always identify same children having SAM. This has generated broad debate, illustrated recent article Grellety & Golden (BMC Nutr. 2016;2:10). Regional variations in proportion of selected each index seem mostly related to differences body shape, including stuntedness. However, practical...
Abstract Background Community health workers (CHWs) are recommended to screen for acute malnutrition in the community by assessing mid-upper arm circumference (MUAC) on children between 6 and 59 months of age. MUAC is a simple screening tool that has been shown be better predictor mortality acutely malnourished than other practicable anthropometric indicators. This study compared, under program conditions, mothers CHWs severe (SAM) color-banded tapes. Methods pragmatic interventional,...
Abstract The Optimising treatment for acute MAlnutrition (OptiMA) strategy trains mothers to use mid upper arm circumference (MUAC) bracelets screening and targets children with MUAC < 125 mm or oedema one therapeutic food at a gradually reduced dose. This study seeks determine whether OptiMA conforms SPHERE standards (recovery rate > 75 %). A single-arm proof-of-concept trial was conducted in 2017 Yako district, Burkina Faso including aged 6–59 months outpatient health centres oedema....
Global access to acute malnutrition treatment is low. Different programmes using different nutritional products manage cases of severe and moderate separately. We aimed assess whether integrating into one programme, a single product reducing the dose as child improves, could achieve similar or higher individual efficacy, increase coverage, minimise costs compared with current programmes.We conducted an open-label, non-inferiority, randomised controlled trial in Democratic Republic Congo....
Current standard management of severe acute malnutrition uses ready-to-use therapeutic food (RUTF) at a single weight-based calculation resulting in an increasing amount RUTF provided to the family as child's weight increases during recovery. Using gradually reduced dosage child recovers could reduce costs while achieving similar growth response.We conducted open-label, non-inferiority, randomised controlled trial Democratic Republic Congo. Children aged 6-59 months with mid-upper-arm...
Abstract Malnutrition impairs cognitive, communication, and motor development, but it is not known how nutrition health are associated with development in children moderate acute malnutrition (MAM). We aimed to describe language of MAM explore its health‐related correlates. This cross‐sectional study used baseline data from a nutritional trial aged 6–23 months Burkina Faso. Motor skills were assessed using the Malawi Development Assessment Tool (MDAT). Linear mixed models potential...
Background Lipid-based nutrient supplements (LNS) and corn–soy blends (CSBs) with varying soy milk content are used in treatment of moderate acute malnutrition (MAM). We assessed the impact these on child development. Methods findings conducted a randomised 2 × 3 factorial trial to assess effectiveness 12 weeks’ supplementation LNS or CSB, either isolate dehulled soy, 0%, 20%, 50% protein from milk, development among 6–23-month-old children MAM. Recruitment took place at 5 health centres...
Abstract Background Simplified approaches of acute malnutrition (AM) treatment have been conducted over the past 5 years intending to unify processes and increase coverage among children aged 6 59 months without medical complication. The Optimsing for Acute Malnutrition (OptiMA) Combined Protocol Study (ComPAS) are mid-upper arm circumference (MUAC)-based treating with MUAC < 125 mm or oedema one sole product—ready-to-use therapeutic food—at a gradually tapered doses. This trial aims...
Globally, access to treatment for severe and moderate acute malnutrition is very low, in part because different protocols products are used separate programs. New approaches, defining (AM) as mid-upper arm circumference (MUAC) < 125 mm or oedema, being investigated compare effectiveness current Optimizing Malnutrition (OptiMA) one such strategy that treats AM with product - ready-to-use therapeutic food, RUTF at reduced dosage the child improves.This study aimed determine whether OptiMA...
In moderate acute malnutrition programs, it is common practice to not measure mid-upper arm circumference (MUAC) of children whose length <67 cm. This based on expert opinion that supplementation shorter with low MUAC and weight-for-height z score ≥-2 may increase risk excessive fat accumulation. Our aim was assess if gain more than taller when treated for diagnosed by alone.In this observational study, we included aged 6 23 months a between 115 125 mm ≥-2. On the basis at admission, were...
Background In the treatment of acute malnutrition (AM), non-response is considered a failure for not meeting recovery criteria within therapeutic window 12–16 weeks, but this category children misunderstood. As current research emphasizes ways to simplify and optimize protocols, emerges as new issue enhance program efficiency. Methods A prospective cohort study was conducted from 2019 2020 at two health centres in Mirriah, Niger among aged 6–59 months with uncomplicated AM treated under...
Abstract The present study aimed to determine the 3-month incidence of relapse and associated factors among children who recovered under Optimising treatment for acute MAlnutrition (OptiMA) strategy, a MUAC-based protocol. A prospective cohort successfully treated malnutrition was monitored between April 2017 February 2018. Children were seen at home by community health workers (CHWs) every 2 weeks 3 months. Relapse defined as child had met OptiMA recovery criteria (MUAC ≥ 125 mm two...
Squirrelpox virus (SQPV) is a significant factor in red squirrel (Sciurus vulgaris) population declines but has previously been unconfirmed the Republic of Ireland. In 2011 juvenile from Wicklow presented with facial, perivulval, and nail bed SQPV skin lesions confirmed by histopathology, PCR, electron microscopy.
Introduction Acute malnutrition (AM) is a continuum condition, arbitrarily divided into moderate and severe AM (SAM) categories, funded managed in separate programmes under different protocols. Optimising acute MAlnutrition (OptiMA) treatment aims to simplify optimise management by treating children with mid-upper arm circumference (MUAC) <125 mm or oedema one product—ready-to-use therapeutic food—at gradually tapered dose. Our main objective was compare the OptiMA strategy standard...
Background: In January 2015, the Alliance for International Medical Action and Bien Être de la Femme et l’Enfant au Niger launched 1000 Days Program in Mirriah District, Niger, to provide an integrated package of maternal pediatric preventive curative interventions. A new component was provision small-quantity lipid-based nutritional supplements (SQ-LNS) children 6 23 months. Objective: The objective this study estimate costs associated with providing days package. Methods: Activity-based...
Abstract Children with moderate acute malnutrition (MAM) are treated based on low weight-for-length z-score (WLZ), mid-upper arm circumference (MUAC) or both. This study aimed to assess associations of admission criteria and body composition (BC), improve treatment MAM. We undertook a cross-sectional among 6–23 months old Burkinabe children Fat-free (FFM) fat mass (FM) were determined by deuterium dilution expressed as FFM (FFMI) FM index (FMI). Of 1,489 children, 439 (29.5%) recruited MUAC...
Abstract Acute malnutrition (AM) causes large loss of life and disability in children Africa. Researchers are testing innovative approaches to increase the efficiency treatment programs This paper presents results a cost-effectiveness analysis one such program Democratic Republic Congo (DRC) based on secondary randomized controlled trial Optimizing Treatment for Malnutrition (OptiMA), conducted DRC 2018–20. A total 896 aged 6–59 months with mid-upper arm circumference (MUAC) &lt;125 mm...
Objectives: Optimising treatment for Acute Malnutrition (OptiMA) and the Combined Protocol malnutrition Study (ComPAS) aim to simplify processes improve efficiency in acute (AM) programming. More evidence is needed such approaches West Africa, specifically among children admitted with Mid-upper arm circumference (MUAC) < 115mm. Methods: This individually randomised, non-inferiority 3-arm trial was conducted Mirriah, Niger 2021-22. Children 6–59 months uncomplicated AM defined as MUAC< 125mm...
The bidirectional interaction between undernutrition and infection can be devastating to child health. Nutritional deficiencies impair immunity increase susceptibility infection. Simultaneously, infections compound by increasing metabolic demand impairing nutrient absorption. Treatment of acute malnutrition (wasting) reverse some its deleterious effects reduce infectious diseases. Nutrition-specific approaches may packaged with other interventions, including immunization, support overall To...
Access to treatment for acute malnutrition remains a challenge, in part due the fragmentation of programmes based on case severity. This paper evaluates utilization patterns, outcomes and associated costs treating cases among cohort children Burkina Faso. study is secondary analysis proof-of-concept trial, called Optimizing Malnutrition (OptiMA), conducted Faso 2016. A total 4958 eligible whose mid-upper arm circumference (MUAC) was less than 125 mm or with oedema were followed weekly given...