A5100365408- Chemokine receptors and signaling
- Prostate Cancer Treatment and Research
- Inflammatory mediators and NSAID effects
- Peripheral Neuropathies and Disorders
- Immunotherapy and Immune Responses
- Parasitic infections in humans and animals
- Estrogen and related hormone effects
- Cancer Mechanisms and Therapy
- Mosquito-borne diseases and control
- Infectious Diseases and Tuberculosis
- Virology and Viral Diseases
- Menopause: Health Impacts and Treatments
- Infectious Encephalopathies and Encephalitis
- Cancer, Stress, Anesthesia, and Immune Response
- Parasites and Host Interactions
- Cancer, Lipids, and Metabolism
- Epilepsy research and treatment
- Parasite Biology and Host Interactions
- Multiple Myeloma Research and Treatments
- Genetics, Bioinformatics, and Biomedical Research
- Malaria Research and Control
- Leprosy Research and Treatment
- Esophageal and GI Pathology
- Liver Disease Diagnosis and Treatment
- PI3K/AKT/mTOR signaling in cancer
King George's Medical University
2016-2025
All India Institute of Medical Sciences
2025
Institute of Microbial Technology
2024
Post Graduate Institute of Medical Education and Research
2015-2024
All India Institute of Medical Sciences Jodhpur
2020-2024
University of Southern California
2024
Saveetha University
2024
Sir Ganga Ram Hospital
2023
Baker Heart and Diabetes Institute
2023
Sardar Vallabhbhai National Institute of Technology Surat
2023
Worldwide, dyes are significant pollutants present in water because of their huge consumption for industrial purposes. These as cause serious health issues human beings and the loss aquatic biodiversity. So, remediation like from wastewater is need hour. In study, we greenly synthesizedSpirulina-mediated titanium oxide nanoparticles (STONPs) adsorptive methyl orange (MO) (anionic) malachite green (MG) (cationic) dyes. The characterization STONPs was performed by Field emission scanning...
This study aimed to evaluate the incidence and clinical spectrum of neurologic complications, predictors central peripheral nervous system involvement, their outcome in patients with dengue virus infection (DENV).To determine extent we used a hospital-based prospective cohort design, which included laboratory-confirmed cases follow-up for 3 months. We also analyzed laboratory data assess involvement.The enrollment 486 cases. Two were lost excluded. Forty-five developed complications. Of...
The focus of this study was to determine the dedicator cytokinesis 2 (DOCK2), extracellular signal-regulated kinase 1/2 (ERK1/2), c-Jun N-terminal kinase-1 (JNK) and Akt signals involved in CXCL13-mediated prostate cancer (PCa) cell invasion proliferation. Androgen-sensitive (LNCaP), hormone-refractory (PC3) cells normal (RWPE-1) were used PCa Immuno-blotting, fast activated cell-based (FACE) ELISA, caspase activity, proliferation assays performed ascertain some signalling events invasion....
Most prostate cancer (PCa)-related deaths are due to metastasis, which is mediated in part by chemokine receptor and corresponding ligand interaction. We have previously shown that PCa tissue cell lines express high levels of the CXCR5, than compared their normal counterparts, interaction CXCR5 with its specific (CXCL13) promoted invasion, migration, differential matrix metalloproteinase (MMP) expression. This study dissects some molecular mechanisms following CXCL13-CXCR5 mediate migration...
Despite recent advances in treatment and management of prostate cancer (PCa), it remains the second leading cause cancer-related deaths among men US. Chemotherapy is one alternatives for hormone refractory metastatic PCa. However, current chemotherapeutic regimens provide palliative benefit but relatively modest survival advantage primarily due to chemo-resistance upregulated antiapoptotic machineries PCa cells. Therefore, blocking mechanisms responsible suppression apoptosis might improve...
// Pranav Gupta 1 , Praveen K. Sharma 2 Hina Mir Rajesh Singh Nalinaksha Goetz H. Kloecker 3 James W. Lillard Jr and Shailesh Morehouse School of Medicine, Atlanta, GA, USA Natural Sciences, Center Life Central University Jharkhand, Ranchi, India Graham Brown Cancer Center, Louisville, KY, Correspondence: Singh, email: Keywords : CCR9, CCL25, Chemokine receptor, Non-small cell lung cancer Received August 05, 2014 Accepted September 24, Published 25, Abstract Poor clinical outcome (LuCa) is...
Background: Rheumatoid arthritis (RA) is a common acute inflammatory autoimmune connective tissue arthropathy. The genetic studies, analyses, experimental animal models, and clinical investigations have confirmed that stromal damage pathology driven by RA mounts the chronic inflammation dysregulated immune events. Methods: We developed methotrexate (MTX)-loaded lipid-polymer hybrid nanoparticles (MTX-LPHNPs) aceclofenac (ACE)-loaded nanostructured lipid carriers (ACE-NLCs) for efficient...
ABSTRACT Endometriosis is an ectopic implantation of uterine tissue and can affect the thoracic cavity, resulting in Thoracic Syndrome (TES). TES rare presents with catamenial pneumothorax, haemothorax, hemoptysis, often coinciding menstruation. We report a case 46-year-old female decade-long history hemoptysis periodic chest pain associated her menstrual cycle. High-resolution CT scans revealed persistent pneumothorax pleural nodules. A dry thoracoscopy was performed, biopsies confirmed...
Abstract Background Prostate cancer (PCa) cell lines and tissues differentially express CXCR5, which positively correlate with PCa progression, mediate migration invasion following interaction CXCL13. However, the differential expression of G protein α, β, γ subunits by precise combination these proteins CXCR5 has not been elucidated. Methods We examined differences in normal prostate (RWPE-1) (LNCaP, C4-2B, PC3) western blot analysis. Further, we immunoprecipitated different subunits,...
Abstract A subset of neuritic form leprosy, called pure leprosy (PNL), seen in a minority patients, is characterized by peripheral neuropathy without skin lesions and an absence acid‐fast bacilli on smears. Patients with PNL are often started drug therapy confirmation diagnosis. We, therefore, did prospective study clinically diagnosed patients correlation ultrasonographic biopsy findings. total 100 consecutive PNL, according to the consensus case definition, were included study. All...
We evaluated seizure profile, Toll-like receptor (TLR)-4 polymorphisms, and serum matrix metalloproteinases (MMPs) in patients with calcified neurocysticercosis. One-hundred nine neurocysticercosis newly diagnosed seizures 109 control subjects were enrolled. TLR-4 Asp299Gly Thr399Ile polymorphisms MMP-9 levels evaluated. The followed for 1 year. Asp/Gly (P = 0.012) Thr/Ile 0.002), Gly (Asp/Gly plus Gly/Gly) 0.008) Ile (Thr/Ile Ile/Ile) 0.003) genotypes significantly associated compared...