A5101419312- Cancer, Hypoxia, and Metabolism
- Hepatocellular Carcinoma Treatment and Prognosis
- Cancer, Lipids, and Metabolism
- Pancreatic and Hepatic Oncology Research
- Epigenetics and DNA Methylation
- Bone health and treatments
- Pancreatic function and diabetes
- Renal cell carcinoma treatment
- Metabolism, Diabetes, and Cancer
- Neuroendocrine Tumor Research Advances
- Liver Disease Diagnosis and Treatment
- Cancer Genomics and Diagnostics
- Organ Transplantation Techniques and Outcomes
- Cancer Diagnosis and Treatment
- Liver physiology and pathology
- Radiation Therapy and Dosimetry
Shanghai Medical College of Fudan University
2014-2019
Fudan University Shanghai Cancer Center
2010-2018
The DNA damage and repair pathway is considered a promising target for developing strategies against cancer. RAD51, also known as RECA, recombinase that performs the critical step in homologous recombination. RAD51 has recently received considerable attention due to its function tumor progression decisive role resistance chemotherapy. However, pancreatic cancer seldom been investigated. In this report, we provide evidence regulated by KRAS, promotes cell proliferation. Furthermore, aerobic...
BACKGROUND:We assessed the role of adjuvant intensity-modulated radiotherapy (IMRT) in combination with chemotherapy for pancreatic carcinomas after curative resection and identified prognostic factors related to carcinoma multidisciplinary treatment strategies. MATERIAL AND METHODS:Pancreatic patients (n=61) who received (median dose, 50.4 Gy) between 2010 2016 were retrospectively identified. Sixty chemotherapy, including concurrent chemoradiotherapy (CCRT), systemic regional...
Surgery is the treatment of choice for pancreatic carcinoma.However,only 20％ patients are eligible surgery,and local control disease and survival not good.Although non-surgical treatments result in poor outcome,chemotherapy has been shown to be an effective treatment.The role irradiation well-established.Modern technology promising results but there still lack strong prospective research evidence support its widespread use.Irradiation brings along problems which need resolved,including...