- Anesthesia and Pain Management
- Pain Mechanisms and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Pain Management and Opioid Use
- Musculoskeletal pain and rehabilitation
- Pediatric Pain Management Techniques
- Pain Management and Placebo Effect
- Abdominal Surgery and Complications
- Hemodynamic Monitoring and Therapy
- Spine and Intervertebral Disc Pathology
- Anesthesia and Sedative Agents
- Wound Healing and Treatments
- Neurosurgical Procedures and Complications
- Minimally Invasive Surgical Techniques
- Neuropeptides and Animal Physiology
- Appendicitis Diagnosis and Management
- Occupational Health and Burnout
- Fatty Acid Research and Health
- Occupational health in dentistry
- Pharmacological Effects of Natural Compounds
- Vitamin K Research Studies
- Pharmacological Effects and Toxicity Studies
- Peroxisome Proliferator-Activated Receptors
- Menstrual Health and Disorders
- Uterine Myomas and Treatments
Universidade de Taubaté
2012-2024
Faculdade de Medicina de Petrópolis
2016-2017
Hospital Municipal São José
2014
Université Lille Nord de France
2011
Master's College
2011
Prefeitura Municipal de Campos dos Goytacazes
2011
Public Health Dayton & Montgomery County
2011
Abstract Introduction The purpose of this study was to evaluate the clinical relevance high values central venous-to-arterial carbon dioxide difference (PCO 2 gap) in high-risk surgical patients admitted a postoperative ICU. We hypothesized that PCO gap could serve as useful tool identify still requiring hemodynamic optimization at ICU admission. Methods One hundred and fifteen were included prospective single-center observational during 1-year period. High-risk inclusion criteria adapted...
Wound healing is characterized by a systemic and complex process of cellular molecular activities. Dipotassium Glycyrrhizinate (DPG), side product derived from glycyrrhizic acid, has several biological effects, such as being antiallergic, antioxidant, antibacterial, antiviral, gastroprotective, antitumoral, anti-inflammatory. This study aimed to evaluate the anti-inflammatory effect topical DPG on cutaneous wounds secondary intention in an vivo experimental model. Twenty-four male Wistar...
BACKGROUND AND OBJECTIVES:Pain is a major complaint of individuals looking for healthcare services.The high prevalence both acute and chronic pain makes it public health problem, due to costs imposed society services, in addition the negative impact on daily activities those living with such experience.This study aimed at identifying among medical students University countryside São Paulo.METHODS: Cross-sectional carried out 395 all grades medicine course Universidade de Taubaté.Investigated...
BACKGROUND AND OBJECTIVES: Self-mutilation is a self-destruction behavior elicited by the desire of self-punishment which may be unconscious and has major impact on individuals' lives.This study aimed at identifying pain intensity satisfies self-mutilation need most, in addition to triggering rewarding factors.METHODS: Cohort study, carried out means questionnaire with participation 20 patients aged above 18 years, treated Psychiatry ambulatory medium-sized city Vale do Paraiba.RESULTS:...
to evaluate the clinical, hemodynamic, gas analysis and metabolic repercussions of high transient pressures pneumoperitoneum for a short period time ensure greater security introduction first trocar. sixty-seven patients undergoing laparoscopic procedures were studied randomly distributed in P12 group: n = 30 (intraperitoneal pressure [IPP] 12 mmHg) P20 37 (IPP 20 mmHg). Mean arterial (MAP) was evaluated by catheterization radial artery; through analysis, pH, partial oxygen (PaO2), CO2...
Musculoskeletal pain is a consequence of repetitive strain, overuse, and work-related musculoskeletal disorders. In 2020, due to the new coronavirus pandemic, social isolation started, so did online classes in remote study strategy replace classroom-based routines. Thus, students adopted different physical posture from usual one for longer time than usual, representing possible risk factor pain. this sense, research aimed identify occurrence medical subject distance learning during COVID-19...
JUSTIFICATIVA E OBJETIVOS: Diversos estudos têm demonstrado os efeitos benéficos dos ácidos graxos ômega-3 à saúde: no metabolismo lipídico, promovendo redução nos níveis plasmáticos triacilgliceróis, aumento de HDL colesterol e, ação anti-inflamatória ao reduzir a síntese derivados do ácido araquidônico: prostaglandina E2 (PGE2), tromboxano A2 (TXA2), prostaciclina (PGI2) e leucotrieno B4. Portanto, há se supor que suplementação com EPA DHA (ω-3), pode atenuar processo inflamatório partir...
BACKGROUND AND OBJECTIVES: Drug administration to children is a widely spread practice, however it may lead several health problems, because in addition medical guidance requires attention of parents and caregivers. This study aimed at identifying the prevalence drug by their tutors, before assistance. METHODS: quantitative descriptive research involving adults who were escorting children, assistance Children's First Aid Unit medium-sized city Vale do Paraíba Paulista months June, July...
avaliar as repercussões clínicas, hemodinâmicas, gasométricas e metabólicas das altas pressões transitórias do pneumoperitônio por curto período de tempo que garantem maior segurança para a introdução primeiro trocarte. foram estudados 67 pacientes submetidos procedimentos videolaparoscópicos aleatoriamente distribuídos em grupo P12: n = 30 (pressão intraperitoneal [PIP] 12 mmHg) P20: 37 (PIP 20 mmHg). Foram avaliados pressão arterial média (PAM), cateterismo da artéria radial; e, mediante...
JUSTIFICATIVA E OBJETIVOS: Há evidências de que a passagem informações nociceptivas pelo corno posterior da medula espinhal (CPME) seguindo para níveis rostrais do sistema nervoso central sofre profundas influências excitatórias e inibitórias. A presente pesquisa teve como objetivo comparar os efeitos metissergida, fentolamina associada à administrados por via subaracnoidea, sobre as fases I, intermediária II teste formalina modificado em ratos. MÉTODO: Foram utilizados 28 ratos Wistar...
BACKGROUND AND OBJECTIVES: Opioids are drugs used to relieve pain, but may cause increased pain sensitivity, known as opioid-induced hyperalgesia, which adversely affects management. This study aimed check if fentanyl, an opioid widely in the clinical practice, produces hyperalgesia that can be attenuated by duloxetine, fluoxetine and pregabalin. METHODS: Thirty male Wistar rats were divided into six groups. The animals group 1 received 1mL of 0.9% saline solution intraperitoneally (IP)...
Dipotassium glycyrrhizinate (DPG) has anti-inflammatory properties, besides promoting the regeneration of skeletal muscle. However, it not been reported on skin wound healing/regeneration. This research aimed to characterize effects DPG in treatment excisional wounds by second intention.Male adults (n=10) and elderly Wistar rats were used. Two circular excised dorsal skin. The normal skins considered adult (GAN) (GIN) naïve. For seven days, 2% was applied proximal excision: treated (GADPG)...
There is evidence that the passage of nociceptive information through posterior horn spinal cord (PHSC) on its way to rostral levels central nervous system undergoes profound excitatory and inhibitory influences. The objective present study was compare effects subarachnoid administration methysergide, phentolamine, phentolamine associated with methysergide phases I, intermediate, II modified phormaline test in rats. Twenty-eight male Wistar rats distributed randomly four groups (n = 7)...
A dengue é um problema de saúde pública no Brasil e a arbovirose mais prevalente mundo. Sua ocorrência município Amarante do Maranhão (MA) tem sido pouco investigada, mas há registros que indicavam elevada presença mosquito transmissor Aedes aegypt nas residências dos munícipes. O objetivo deste trabalho foi investigar as ocorrências quanto ao número casos, faixa etária contraíram, sorotipos circulantes vírus hospitalizações por causa da dengue, período entre 2014 2020. Os dados foram...
JUSTIFICATIVA E OBJETIVOS: Diversos sistemas de receptores estão envolvidos na modulação central da dor: noradrenérgico, serotoninérgico e opioide, entre outros. O objetivo foi estudar os efeitos amitriptilina sobre a dor em ratos, após ligadura do nervo ciático. MÉTODO: Foram estudados 24 ratos Wistar, machos, com peso médio 300g, distribuídos 5 grupos: (C) controle sem tratamento (n = 4), (LC) submetidos à ciático 5), tratados com: (A) (R) reserpina (AR) + amitriptilina. Todos animais...
Background: Breast cancer is increasingly common in society and post-mastectomy pain a striking condition associated with surgery, both intra postoperatively. The syndrome characterized by the persistence of for more than 3 months after procedure. It mostly neuropathic origin highly refractory to treatments, which vary from clinical surgical measures alternative techniques. In this context, it essential understand possible approaches these patients. Objective: Understand alternatives...
Painful phenomenon is one of the most important and complex experiences. Phentolamine a non-selective alpha-adrenergic antagonist. The objective this study was to compare effect increasing doses phentolamine into subarachnoid space in rats modulation painful phenomenon. 84 male Wistar were divided formalin plantar incision groups, subdivided six subgroups (n = 7). Control group received only saline (10 μL); active 10 μmg (GF10), 20 mg (GF20), 30 (GF30), 40 (GF40), 50 g (GF50). In group, pain...
The use of agricultural pesticides in Brazil has significantly increased during recent decades, especially due to the competition between internal Brazilian market and that for exports. Pesticides are among most important risk factors health general population, workers, environment, resulting a scenario public spending on social damage pollution by such chemicals, with emphasis organophosphates carbamates. When these substances managed incorrectly, as when personal protection equipment (PPE)...
Painful phenomenon is one of the most important and complex experiences. Phentolamine a non-selective alpha-adrenergic antagonist. The objective this study was to compare effect increasing doses phentolamine into subarachnoid space in rats modulation painful phenomenon.84 male Wistar were divided formalin plantar incision groups, subdivided six subgroups (n=7). Control group (CG) received only saline (10μL); active 10μmg (GF10), 20mg (GF20), 30mg (GF30), 40mg (GF40), 50g (GF50). In group,...
evaluar las repercusiones clínicas, hemodinámicas, gasométricas y metabólicas de altas presiones transitorias del neumoperitoneo durante un corto período tiempo para garantizar una mayor seguridad en la introducción primer trocar. fueron estudiados 67 pacientes sometidos a procedimientos videolaparoscópicos distribuidos aleatoriamente grupo P12: n = 30 (presión intraperitoneal [PIP] 12 mmHg), P20: 37 (PIP 20 mmHg). Se evaluó presión arterial media por cateterismo arteria radial; mediante...
JUSTIFICATIVA E OBJETIVOS: O planejamento da analgesia no tratamento dor aguda pós-operatória é fundamental para o seu controle efetivo, pois quando não tratada acarreta alterações nocivas ao organismo. Este estudo teve como objetivo analisar a mudança na prescrição de analgésicos período pós-operatório cirurgias ginecológicas antes e após apresentação simpósio fornecimento manual sobre dor. MÉTODO: Estudo prospectivo com 72 pacientes, idade entre 18 80 anos, submetidas à ginecológicas,...