Shuo Xiao

ORCID: 0000-0002-7035-5451
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About
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Research Areas
  • Signaling Pathways in Disease
  • Heart Failure Treatment and Management
  • Cardiac Fibrosis and Remodeling

Circulating proteomic signatures of age are closely associated with aging and age-related diseases; however, the utility changes in secreted proteins identifying therapeutic targets for diseases remains unclear. Serum profiling an age-stratified healthy population further community-based cohort together heart failure patients study demonstrated that circulating C-C motif chemokine ligand 17 (CCL17) level increased correlated cardiac dysfunction. Subsequent animal experiments revealed...

10.1084/jem.20200418 article EN cc-by The Journal of Experimental Medicine 2022-06-10
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