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Research Areas
- Signaling Pathways in Disease
- Heart Failure Treatment and Management
- Cardiac Fibrosis and Remodeling
Circulating proteomic signatures of age are closely associated with aging and age-related diseases; however, the utility changes in secreted proteins identifying therapeutic targets for diseases remains unclear. Serum profiling an age-stratified healthy population further community-based cohort together heart failure patients study demonstrated that circulating C-C motif chemokine ligand 17 (CCL17) level increased correlated cardiac dysfunction. Subsequent animal experiments revealed...
10.1084/jem.20200418
article
EN
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The Journal of Experimental Medicine
2022-06-10
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