A5020418432- Corporate Finance and Governance
- Acupuncture Treatment Research Studies
- Bioactive Compounds and Antitumor Agents
- Natural product bioactivities and synthesis
- Financial Markets and Investment Strategies
- Lipid metabolism and disorders
- Atrial Fibrillation Management and Outcomes
- Auditing, Earnings Management, Governance
- Morinda citrifolia extract uses
- Sustainable Agricultural Systems Analysis
- Phytochemistry and Bioactive Compounds
- Land Use and Ecosystem Services
- Diet and metabolism studies
- Forest Management and Policy
- Cardiac Fibrosis and Remodeling
- Plant Ecology and Soil Science
- Hippo pathway signaling and YAP/TAZ
- Forest, Soil, and Plant Ecology in China
- Bioactive natural compounds
- Genomics and Rare Diseases
- Signaling Pathways in Disease
- Medicinal plant effects and applications
- Peptidase Inhibition and Analysis
- Nitrogen and Sulfur Effects on Brassica
- Phytochemical compounds biological activities
International Monetary Fund
2024
The Ohio State University
2024
Central South University
2024
Second Xiangya Hospital of Central South University
2024
Beijing Tsinghua Chang Gung Hospital
2023
Macau University of Science and Technology
2023
Peking Union Medical College Hospital
2020-2022
Chinese Academy of Medical Sciences & Peking Union Medical College
2003-2022
XinHua Hospital
2018-2021
First Hospital of Jilin University
2020
Circulating proteomic signatures of age are closely associated with aging and age-related diseases; however, the utility changes in secreted proteins identifying therapeutic targets for diseases remains unclear. Serum profiling an age-stratified healthy population further community-based cohort together heart failure patients study demonstrated that circulating C-C motif chemokine ligand 17 (CCL17) level increased correlated cardiac dysfunction. Subsequent animal experiments revealed...
Abstract Background Rare disease patients often experience diagnosis delays or misdiagnosis, which may be due to lack of knowledge on rare diseases among physicians. Objective To assess Chinese physicians’ specific and identify its associated factors. Methods Thirty-four patient organizations with a unique interest were invited develop 3 questions for each the that they felt most experienced in. The total score participant ranged from 0 3. A national cross-sectional study conducted in cohort...
<b><i>Objectives:</i></b> This study aimed to investigate the roles of connective tissue growth factor (CTGF) and transforming factor-β<sub>1</sub> (TGF-β<sub>1</sub>) in atrial fibrosis patients with chronic fibrillation. <b><i>Methods:</i></b> Up 40 cases involving simple mitral valve replacement surgery were divided into 2 groups: fibrillation (cAF) group (n = 28) sinus rhythm 12). Echocardiography was used measure...
Abstract Atrial fibrillation (AF) is the most common cardiac arrhythmia nowadays. The occurrence of AF closely associated with obesity. Cadherin‐11 (Cad‐11), as a member cadherin family, can make contribution to diet‐induced obesity and it will be informative know whether Cad‐11 exerts its effects on atrial remodeling vulnerability in model. In this study, we demonstrated that expression was significantly upregulated left atrium patients mice following 16 weeks high‐fat diet (HFD) feeding....
Grassland, as one of the largest ecosystems on earth, supports various goods and services to humanity. Historically, humans have increased agricultural output primarily by cropland expansion intensification. The area was gained at expense grassland forests. Apart from conversion, increasing consumption calorie- meat-intensive diets drives intensification livestock systems, which is shifting steadily grazing feeding with crops. To cope environmental degradation due agriculture, forms 'green...
As the most frequent fungal pathogen in humans, Candida albicans can develop serious drug resistance because its biofilms are resistant to antifungal agents; this leads an urgent need novel antifungals. Here, we evaluated efficacy of antithrombotic drug, suloctidil, against C. vitro and vivo. We found that suloctidil is effective inhibit biofilm, with a minimum inhibitory concentration (MIC80) 4 μg/mL, biofilm inhibiting (BIC80) 16 μg/mL eradicating (BEC80) 64 μg/mL. Furthermore,...
Background and Purpose 9‐Phenanthrol, known as a specific inhibitor of the transient receptor potential melastatin 4 (TRMP4) channel, has been shown to modulate cardiac electrical activity exert antiarrhythmic effects. However, its pharmacological effects remain be fully explored. Here, we tested hypothesis that sodium current inhibition contributes cardioprotective effect 9‐phenanthrol. Experimental Approach Single ventricular myocytes (VMs) Purkinje cells (PCs) were enzymatically isolated...
We demonstrate that relatively high revenue growth prior to an initial public offering (IPO) is associated with IPO prices and poor returns. In particular, low‐growth returns, −1% on a three‐year annualized basis compared −12% (equal‐weighted) or −29% (value‐weighted) for high‐growth new issues. There no evidence the performance differentials reflect risk premia. Rather, firms’ returns are more stable over time. Finally, while analysts’ forecasts upwardly biased all firms, magnitude of this...
Two new type dicoumarins (dicoumaro-p-menthanes), named dibothrioclinins I (1) and II (2) were isolated from the roots rhizomes of Gerbera piloselloides (L.) CASS., collected in Yunnan Province, China. Their structures elucidated on basis MS, 1D (1H-NMR, 13C-NMR, DEPT NOE) 2D (1H–1H COSY, HMQC, HMBC) NMR spectral analyses. The relative two compounds established by NOE difference spectroscopy further confirmed single-crystal X-ray diffraction studies.
This article investigates how “systematic” adjustment costs proxied by market imperfections, and macroeconomic conditions affect capital structure dynamics in a cross-country setting. We document substantial variations firms’ adjustments across countries and, particularly, over time. Consistent with impeding firms from rebalancing their structures, worse imperfections are associated slower speeds of (SOA) larger leverage deviations. Intertemporally, is procyclical, SOA increasing 0.9...
Background Extrahepatic biliary duct injury (BDI) remains a complicated issue for surgeons. Although several approaches have been explored to address this problem, the high incidence of complications affects postoperative recovery. As nonimmunogenic scaffold, an animal-derived artificial bile (ada-BD) could replace defect, providing good physiological conditions regeneration autologous structures without changing original anatomical and physiologic conditions. Aim To evaluate long-term...
The forest-fire not only brings great loss to natural resources, but also destructs the ecosystem and reduces soil fertility, causing some disasters as erosion debris flow. However, due lack of prognosis for forest fire spreading trend in fighting, it is difficult formulate rational effective fire-fighting scheme. In event fire, achieving accurate judgment behavior would greatly improve efficiency, reduce heavy losses caused by fire. Researches on spread simulation can effectively disasters....
Background: Burnout symptoms are an underlying barrier to the health-related well-being of health professionals, however, association between burnout and capability has not been identified yet. Chinese medical staff especially vulnerable for due heavy workload worsened physician-patient relationships. The objective study is determine profile professionals with at national level identify burnout.Methods: A cross-sectional in a nonrandom sample from 6 provinces across western, central eastern...