Jian Zhao

ORCID: 0000-0002-1306-1676
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About
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Research Areas
  • Liver Disease Diagnosis and Treatment
  • Genetic Associations and Epidemiology
  • Ovarian function and disorders
  • Genetic and phenotypic traits in livestock
  • Birth, Development, and Health
  • Gastric Cancer Management and Outcomes
  • Breastfeeding Practices and Influences
  • Colorectal Cancer Surgical Treatments
  • Folate and B Vitamins Research
  • Estrogen and related hormone effects
  • Child Nutrition and Water Access
  • Diet and metabolism studies
  • Epigenetics and DNA Methylation
  • Emergency and Acute Care Studies
  • Bone health and treatments
  • Kawasaki Disease and Coronary Complications
  • Diet, Metabolism, and Disease
  • Reproductive Biology and Fertility
  • Bone health and osteoporosis research
  • Lipid metabolism and disorders
  • Connective tissue disorders research
  • GDF15 and Related Biomarkers
  • Gene expression and cancer classification
  • Gestational Diabetes Research and Management
  • Anorectal Disease Treatments and Outcomes

China Academy of Space Technology
2025

First Affiliated Hospital of Anhui Medical University
2022-2025

Southern University of Science and Technology
2022-2024

MRC Epidemiology Unit
2020-2024

University of Bristol
2019-2024

Tibet Autonomous Region People's Hospital
2024

Affiliated Hospital of North Sichuan Medical College
2024

Geely (China)
2024

XinHua Hospital
2021-2024

Shanghai Jiao Tong University
2006-2024

Urinary and sexual dysfunction is the potential complication of rectal cancer surgery. The aim this study was to evaluate urinary function in male patients with robotic surgery for cancer.This prospective included 137 336 who underwent cancer. studied by means a questionnaire based on International Prostatic Symptom Score Index Erectile Function. All data were collected before 12 months after surgery.Patients had significantly decreased incidence partial or complete erectile than...

10.1002/rcs.1725 article EN International Journal of Medical Robotics and Computer Assisted Surgery 2016-01-08

Background Robotic gastrectomy is increasingly used in gastric cancer patients. This study assessed the safety and efficacy of full robotic with intracorporeal robot-sewn anastomosis for cancer. Methods Three hundred eleven patients were randomized into an open group or a group, digestive restorations performed under direct vision anastomosis, respectively. Length postoperative hospital stay, number lymph node dissections, surgical duration, blood loss, complication rate after surgery...

10.1002/jso.24146 article EN Journal of Surgical Oncology 2016-01-12

ABSTRACT Osteoporosis is a global bone disease characterized by reduced mineral density (BMD) and increased risk of fractures. The developing osteoporosis increases with aging, especially after menopause in women. Discovering the signaling pathways that play significant role aging- menopause-induced should accelerate drug discovery. In this study, we found bile acid membrane receptor Tgr5 knockout C57BL/6J mice had similar mass as wild-type during early middle-age (before 4 months old)...

10.1002/jbmr.3652 article EN Journal of Bone and Mineral Research 2018-12-07

Abstract Purpose The choice of continuous renal replacement therapy (CRRT) anticoagulation program for patients at high risk bleeding has always been a complex problem in clinical practice. Clinical regimens include regional citrate (RCA) and nafamostat mesylate (NM). This study aimed to evaluate the efficacy safety these two anticoagulants CRRT guide their use better. Patients methods Between January 2021 December 2022, 307 were screened this study. Forty-six finally enrolled: 22 group 24...

10.1186/s40001-024-01660-7 article EN cc-by European journal of medical research 2024-01-20

Focusing on a plunger type constant current output device designed for high sealing and long-life with complex multi-component coupling composition, assembly precision, many influencing factors other manufacturing problems, based the in-depth analysis of precision mechanism operational performance, surface quality structure, axial runout system structural dimensional accuracy are accurately controlled by error corresponding design; The decouples rotational screw to propose directional method...

10.1117/12.3045172 article EN 2025-01-16

Intraoperative and postoperative data collected from patients with low rectal cancer who had undergone robotic laparoscopic intersphincteric resection (ISR) procedures were retrospectively analyzed to evaluate factors linked anastomotic leakage recovery of urinary function, bowel control, long-term prognosis. This single-center study enrolled ISR (n = 150) or January 2016 July 2019. The respective mean tumor distances the anal margin in groups 3.94 ± 0.48 cm 5.66 0.47 cm, while times...

10.1007/s00384-025-04844-7 article EN cc-by-nc-nd International Journal of Colorectal Disease 2025-02-27

<title>Abstract</title> <bold>Summary: </bold>This 4-month study was conducted in 64 white rabbits.The correlation between the microstructure, micro-mechanical properties and macroscopic mechanical strength of BTMs, bone trabeculae investigated. CTX-I showed strongest with microstructure micromechanical properties, while OC strength. <bold>Objective:</bold> To investigate variation patterns correlations among serum turnover markers (BTMs), trabecular bone, macro-mechanical during process...

10.21203/rs.3.rs-6161804/v1 preprint EN cc-by Research Square (Research Square) 2025-03-31

&lt;b&gt;&lt;i&gt;Objectives:&lt;/i&gt;&lt;/b&gt; This study aimed to investigate the roles of connective tissue growth factor (CTGF) and transforming factor-β&lt;sub&gt;1&lt;/sub&gt; (TGF-β&lt;sub&gt;1&lt;/sub&gt;) in atrial fibrosis patients with chronic fibrillation. &lt;b&gt;&lt;i&gt;Methods:&lt;/i&gt;&lt;/b&gt; Up 40 cases involving simple mitral valve replacement surgery were divided into 2 groups: fibrillation (cAF) group (n = 28) sinus rhythm 12). Echocardiography was used measure...

10.1159/000347126 article EN Cardiology 2013-01-01

Amino acids are key to protein synthesis, energy metabolism, cell signaling and gene expression; however, the contribution of specific maternal amino fetal growth is unclear.

10.1016/j.ebiom.2023.104441 article EN cc-by EBioMedicine 2023-01-23

We aimed to prospectively evaluate the associations between baseline and changes in high-density C-reactive protein (hs-CRP) incident metabolic syndrome (MetS) China update evidence based on a meta-analysis of cohort studies different populations.Data from Health Retirement Longitudinal Study among adults aged 45 years or older were analyzed. Participants who recruited study 2011-2012 without MetS successfully followed up 2015-2016 included our final analysis. Logistic regressions applied...

10.1186/s12986-021-00632-6 article EN cc-by Nutrition & Metabolism 2022-01-06

The activation of hypoxia-inducible factor 1α (HIF-1α) signaling has promising implications for the treatment bone diseases such as osteoporosis and skeletal fractures. However, effects manipulating HIF-1α pathway on micro-structure remodeling should be fully studied before clinical application therapeutics that interfere with pathway. In this study, we found osteocyte-specific had critical role in mass accrual, material properties micro-structures, including mineralization, collagen fiber...

10.3389/fcell.2021.721561 article EN cc-by Frontiers in Cell and Developmental Biology 2022-01-18

BACKGROUNDThe insulin-like growth factor 1 (IGF1) gene, which plays a crucial role in hypothalamic–pituitary–ovarian hormone-controlled metabolic processes, may influence the onset of menarche. Our study aimed to test association between IGF1 polymorphisms with variation age at menarche (AAM) Caucasian females.

10.1093/humrep/dem052 article EN Human Reproduction 2007-03-21
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